tumorigenic Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

215 genes co-occuring with the biological term tumorigenic in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ADAM17 ADAM metallopeptidase domain 17
ADGRG1 adhesion G protein-coupled receptor G1
ADIPOQ adiponectin, C1Q and collagen domain containing
ADM adrenomedullin
AGO2 argonaute RISC catalytic component 2
AHR aryl hydrocarbon receptor
AHSG alpha-2-HS-glycoprotein
AICDA activation-induced cytidine deaminase
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALK anaplastic lymphoma receptor tyrosine kinase
ANXA2 annexin A2
AR androgen receptor
AREG amphiregulin
ASCL1 achaete-scute family bHLH transcription factor 1
ATF3 activating transcription factor 3
ATPIF1 ATPase inhibitory factor 1
ATR ATR serine/threonine kinase
BCDIN3D BCDIN3 domain containing
BCL2 B-cell CLL/lymphoma 2
BLM Bloom syndrome, RecQ helicase-like
BMI1 BMI1 proto-oncogene, polycomb ring finger
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
CADM3 cell adhesion molecule 3
CADM4 cell adhesion molecule 4
CAPG capping protein (actin filament), gelsolin-like
CCKBR cholecystokinin B receptor
CD44 CD44 molecule (Indian blood group)
CD9 CD9 molecule
CDX2 caudal type homeobox 2
CGA glycoprotein hormones, alpha polypeptide
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal)
CLDN6 claudin 6
CLDN7 claudin 7
CLDN9 claudin 9
CLU clusterin
CREBBP CREB binding protein
CRTC2 CREB regulated transcription coactivator 2
CTBP2 C-terminal binding protein 2
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCR4 chemokine (C-X-C motif) receptor 4
CYLD cylindromatosis (turban tumor syndrome)
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DAXX death-domain associated protein
E2F4 E2F transcription factor 4, p107/p130-binding
EGFR epidermal growth factor receptor
ELAVL1 ELAV like RNA binding protein 1
EPAS1 endothelial PAS domain protein 1
ERAS ES cell expressed Ras
ERBB2 erb-b2 receptor tyrosine kinase 2
ESRRA estrogen-related receptor alpha
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EWSR1 EWS RNA-binding protein 1
EXOC2 exocyst complex component 2
EXOC8 exocyst complex component 8
EZR ezrin
FANCL Fanconi anemia, complementation group L
FASLG Fas ligand (TNF superfamily, member 6)
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLT1 fms-related tyrosine kinase 1
GLI1 GLI family zinc finger 1
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPR39 G protein-coupled receptor 39
GRB7 growth factor receptor-bound protein 7
H19 H19, imprinted maternally expressed transcript (non-protein coding)
HAPLN1 hyaluronan and proteoglycan link protein 1
HBEGF heparin-binding EGF-like growth factor
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMGA1 high mobility group AT-hook 1
HMGN1 high mobility group nucleosome binding domain 1
HMOX1 heme oxygenase 1
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGF2R insulin-like growth factor 2 receptor
IL17RD interleukin 17 receptor D
IL6ST interleukin 6 signal transducer
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
ISG15 ISG15 ubiquitin-like modifier
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB5 integrin, beta 5
JUN jun proto-oncogene
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCND1 potassium channel, voltage gated Shal related subfamily D, member 1
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF4 Kruppel-like factor 4 (gut)
KLK11 kallikrein-related peptidase 11
LGALS1 lectin, galactoside-binding, soluble, 1
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MCM3 minichromosome maintenance complex component 3
MED1 mediator complex subunit 1
MET MET proto-oncogene, receptor tyrosine kinase
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR145 microRNA 145
MIR21 microRNA 21
MIR340 microRNA 340
MIR34A microRNA 34a
MIR382 microRNA 382
MIRLET7A1 microRNA let-7a-1
MMP1 matrix metallopeptidase 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MST1R macrophage stimulating 1 receptor
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
NEK2 NIMA-related kinase 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOB1 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
NOTCH2 notch 2
NTSR1 neurotensin receptor 1 (high affinity)
OGFR opioid growth factor receptor
PADI4 peptidyl arginine deiminase, type IV
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PALLD palladin, cytoskeletal associated protein
PARK2 parkin RBR E3 ubiquitin protein ligase
PAX8 paired box 8
PDGFB platelet-derived growth factor beta polypeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PDZK1IP1 PDZK1 interacting protein 1
PELP1 proline, glutamate and leucine rich protein 1
PHB prohibitin
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PIWIL1 piwi-like RNA-mediated gene silencing 1
PLAG1 pleiomorphic adenoma gene 1
PLD1 phospholipase D1, phosphatidylcholine-specific
PMEPA1 prostate transmembrane protein, androgen induced 1
POU4F1 POU class 4 homeobox 1
PPARG peroxisome proliferator-activated receptor gamma
PRAME preferentially expressed antigen in melanoma
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PROM1 prominin 1
PSCA prostate stem cell antigen
PTEN phosphatase and tensin homolog
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGES prostaglandin E synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH1R parathyroid hormone 1 receptor
PTHLH parathyroid hormone-like hormone
PTN pleiotrophin
RAD51 RAD51 recombinase
RB1 retinoblastoma 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REST RE1-silencing transcription factor
RND3 Rho family GTPase 3
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPSA ribosomal protein SA
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SELENBP1 selenium binding protein 1
SLIT2 slit homolog 2 (Drosophila)
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMO smoothened, frizzled class receptor
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SNAI1 snail family zinc finger 1
SNAI2 snail family zinc finger 2
SOCS1 suppressor of cytokine signaling 1
SOX2 SRY (sex determining region Y)-box 2
SOX9 SRY (sex determining region Y)-box 9
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SRPK1 SRSF protein kinase 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STK17B serine/threonine kinase 17b
TCL1A T-cell leukemia/lymphoma 1A
TDGF1 teratocarcinoma-derived growth factor 1
TFF2 trefoil factor 2
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TGFBI transforming growth factor, beta-induced, 68kDa
TIMP3 TIMP metallopeptidase inhibitor 3
TLR4 toll-like receptor 4
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TP53 tumor protein p53
TSPYL2 TSPY-like 2
TWIST1 twist family bHLH transcription factor 1
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum)
UBIAD1 UbiA prenyltransferase domain containing 1
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
USP18 ubiquitin specific peptidase 18
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VIM vimentin
WNT1 wingless-type MMTV integration site family, member 1
WNT5A wingless-type MMTV integration site family, member 5A
WTAP Wilms tumor 1 associated protein
XCR1 chemokine (C motif) receptor 1
YBX1 Y box binding protein 1
ZFP42 ZFP42 zinc finger protein