tumor necrosis factor-alpha Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Tumor necrosis factor (TNF, cachexin or cachectin formerly known as tumor necrosis factor-alpha or TNF-α) is a cytokine involved in systemic inflammation and is a member of a group of cytokines that stimulate the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by other cell types as well. (Experimental Factor Ontology, EFO_0003271)
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Genes

13 genes associated with the disease tumor necrosis factor-alpha in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
AHCYL2 adenosylhomocysteinase-like 2
AVEN apoptosis, caspase activation inhibitor
CHRM5 cholinergic receptor, muscarinic 5
EMC7 ER membrane protein complex subunit 7
GLRB glycine receptor, beta
IKZF2 IKAROS family zinc finger 2 (Helios)
MED12L mediator complex subunit 12-like
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma
PPA1 pyrophosphatase (inorganic) 1
SPON1 spondin 1, extracellular matrix protein
TMEM117 transmembrane protein 117
WDR70 WD repeat domain 70