tuberculosis Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
Description A primary bacterial infectious disease that is located_in lungs, located_in lymph nodes, located_in pericardium, located_in brain, located_in pleura or located_in gastrointestinal tract, has_material_basis_in Mycobacterium tuberculosis, which is transmitted_by droplets released into the air when an infected person coughs or sneezes. (Human Disease Ontology, DOID_399)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:399
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Genes

72 genes associated with the disease tuberculosis in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
SLC14A2 solute carrier family 14 (urea transporter), member 2 1.33495
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 1.31635
C2CD2 C2 calcium-dependent domain containing 2 1.28906
IL2RB interleukin 2 receptor, beta 1.28906
STXBP5 syntaxin binding protein 5 (tomosyn) 1.19386
CDH13 cadherin 13 1.14463
DCUN1D5 DCN1, defective in cullin neddylation 1, domain containing 5 1.14463
PARD3B par-3 family cell polarity regulator beta 1.14463
DSCAM Down syndrome cell adhesion molecule 1.14463
ZFPM2 zinc finger protein, FOG family member 2 1.10764
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit 1.10764
DUSP14 dual specificity phosphatase 14 1.10764
ZNF229 zinc finger protein 229 1.07599
VWA8 von Willebrand factor A domain containing 8 1.04846
MYO1D myosin ID 1.03672
CHN1 chimerin 1 1.01024
AHCYL2 adenosylhomocysteinase-like 2 0.971169
SPON1 spondin 1, extracellular matrix protein 0.971169
FHIT fragile histidine triad 0.962623
CD226 CD226 molecule 0.940135
GFOD1 glucose-fructose oxidoreductase domain containing 1 0.92437
AKNAD1 AKNA domain containing 1 0.916706
ACBD6 acyl-CoA binding domain containing 6 0.915976
DNAH11 dynein, axonemal, heavy chain 11 0.915252
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 0.900854
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.893189
PTPRD protein tyrosine phosphatase, receptor type, D 0.865448
XYLT1 xylosyltransferase I 0.862443
NCKAP5 NCK-associated protein 5 0.859982
UBXN11 UBX domain protein 11 0.858922
ANO2 anoctamin 2, calcium activated chloride channel 0.856323
SAMD4A sterile alpha motif domain containing 4A 0.850837
UBASH3B ubiquitin associated and SH3 domain containing B 0.848917
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 0.838141
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 0.833585
PLS1 plastin 1 0.832379
RBL2 retinoblastoma-like 2 0.824363
SGIP1 SH3-domain GRB2-like (endophilin) interacting protein 1 0.819929
COL12A1 collagen, type XII, alpha 1 0.817977
SDK1 sidekick cell adhesion molecule 1 0.817591
AKR1C3 aldo-keto reductase family 1, member C3 0.817207
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 0.813813
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing 0.813075
UBA6 ubiquitin-like modifier activating enzyme 6 0.807012
ERBB4 erb-b2 receptor tyrosine kinase 4 0.806323
KLF12 Kruppel-like factor 12 0.804959
NPAS3 neuronal PAS domain protein 3 0.795979
LEKR1 leucine, glutamate and lysine rich 1 0.794591
CSMD1 CUB and Sushi multiple domains 1 0.794247
REPS2 RALBP1 associated Eps domain containing 2 0.775167
VSTM2A V-set and transmembrane domain containing 2A 0.773189
SGMS1 sphingomyelin synthase 1 0.772353
SOX6 SRY (sex determining region Y)-box 6 0.77043
TMEM51 transmembrane protein 51 0.768778
ZNF318 zinc finger protein 318 0.760137
C17ORF78 chromosome 17 open reading frame 78 0.759585
IGSF21 immunoglobin superfamily, member 21 0.74072
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 0.724198
LRP1B low density lipoprotein receptor-related protein 1B 0.716576
GEMIN7 gem (nuclear organelle) associated protein 7 0.708888
SCD5 stearoyl-CoA desaturase 5 0.706444
MRRF mitochondrial ribosome recycling factor 0.69739
SLIT3 slit homolog 3 (Drosophila) 0.688149
GALNT13 polypeptide N-acetylgalactosaminyltransferase 13 0.680822
DNAH8 dynein, axonemal, heavy chain 8 0.680104
ARNTL aryl hydrocarbon receptor nuclear translocator-like 0.67631
CCDC148 coiled-coil domain containing 148 0.662072
LHFP lipoma HMGIC fusion partner 0.657565
LRP2 low density lipoprotein receptor-related protein 2 0.587807
RANBP3L RAN binding protein 3-like 0.568186
ERP44 endoplasmic reticulum protein 44 0.554406
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.545546