tuberculosis Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A primary bacterial infectious disease that is located_in lungs, located_in lymph nodes, located_in pericardium, located_in brain, located_in pleura or located_in gastrointestinal tract, has_material_basis_in Mycobacterium tuberculosis, which is transmitted_by droplets released into the air when an infected person coughs or sneezes. (Human Disease Ontology, DOID_399)
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Genes

81 genes associated with the disease tuberculosis in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACP1 acid phosphatase 1, soluble
AHCYL2 adenosylhomocysteinase-like 2
BTNL2 butyrophilin-like 2
C3 complement component 3
CCL2 chemokine (C-C motif) ligand 2
CCL3 chemokine (C-C motif) ligand 3
CCL5 chemokine (C-C motif) ligand 5
CD14 CD14 molecule
CD209 CD209 molecule
CDH13 cadherin 13
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR2 chemokine (C-X-C motif) receptor 2
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DUSP14 dual specificity phosphatase 14
ESD esterase D
FZD5 frizzled class receptor 5
GC group-specific component (vitamin D binding protein)
GLO1 glyoxalase I
GSTM1 glutathione S-transferase mu 1
GSTT1 glutathione S-transferase theta 1
HLA-C major histocompatibility complex, class I, C
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IL10 interleukin 10
IL12B interleukin 12B
IL12RB1 interleukin 12 receptor, beta 1
IL12RB2 interleukin 12 receptor, beta 2
IL13 interleukin 13
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL4 interleukin 4
IL6 interleukin 6
IRF1 interferon regulatory factor 1
IRGM immunity-related GTPase family, M
KIF3A kinesin family member 3A
LTA lymphotoxin alpha
MBL2 mannose-binding lectin (protein C) 2, soluble
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NOD2 nucleotide-binding oligomerization domain containing 2
NOS2 nitric oxide synthase 2, inducible
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PACRG PARK2 co-regulated
PARD3B par-3 family cell polarity regulator beta
PARK2 parkin RBR E3 ubiquitin protein ligase
PGM1 phosphoglucomutase 1
RAD50 RAD50 homolog (S. cerevisiae)
SEPT8 septin 8
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFTPA1 surfactant protein A1
SFTPA2 surfactant protein A2
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SLCO1B3 solute carrier organic anion transporter family, member 1B3
STAT1 signal transducer and activator of transcription 1, 91kDa
STXBP5 syntaxin binding protein 5 (tomosyn)
TF transferrin
TGFB1 transforming growth factor, beta 1
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TLR1 toll-like receptor 1
TLR10 toll-like receptor 10
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR6 toll-like receptor 6
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
UBE3A ubiquitin protein ligase E3A
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WNT5A wingless-type MMTV integration site family, member 5A
ZNF229 zinc finger protein 229