tube morphogenesis Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The process in which the anatomical structures of a tube are generated and organized. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system. (Gene Ontology, GO_0035239)
External Link http://amigo.geneontology.org/amigo/term/GO:0035239
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Genes

228 genes participating in the tube morphogenesis biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ACVR1 activin A receptor, type I
ACVRL1 activin A receptor type II-like 1
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AHI1 Abelson helper integration site 1
AREG amphiregulin
ARL13B ADP-ribosylation factor-like 13B
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BBS4 Bardet-Biedl syndrome 4
BBS5 Bardet-Biedl syndrome 5
BBS7 Bardet-Biedl syndrome 7
BCL2 B-cell CLL/lymphoma 2
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BMP7 bone morphogenetic protein 7
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C2CD3 C2 calcium-dependent domain containing 3
CCDC103 coiled-coil domain containing 103
CCDC39 coiled-coil domain containing 39
CCDC40 coiled-coil domain containing 40
CCL11 chemokine (C-C motif) ligand 11
CCM2 cerebral cavernous malformation 2
CD44 CD44 molecule (Indian blood group)
CHD7 chromodomain helicase DNA binding protein 7
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CLIC4 chloride intracellular channel 4
COL4A1 collagen, type IV, alpha 1
CSF1 colony stimulating factor 1 (macrophage)
CSF1R colony stimulating factor 1 receptor
CSNK2B casein kinase 2, beta polypeptide
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNNBIP1 catenin, beta interacting protein 1
CTSZ cathepsin Z
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR4 chemokine (C-X-C motif) receptor 4
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DCHS1 dachsous cadherin-related 1
DDR1 discoidin domain receptor tyrosine kinase 1
DICER1 dicer 1, ribonuclease type III
DLG1 discs, large homolog 1 (Drosophila)
DLG5 discs, large homolog 5 (Drosophila)
DLL1 delta-like 1 (Drosophila)
DLL4 delta-like 4 (Drosophila)
DNAAF1 dynein, axonemal, assembly factor 1
EDN1 endothelin 1
EDNRA endothelin receptor type A
EGF epidermal growth factor
EGFR epidermal growth factor receptor
ENG endoglin
EPHA2 EPH receptor A2
EPHB3 EPH receptor B3
ESR1 estrogen receptor 1
ETV4 ets variant 4
EYA1 EYA transcriptional coactivator and phosphatase 1
FAT4 FAT atypical cadherin 4
FGF10 fibroblast growth factor 10
FGF2 fibroblast growth factor 2 (basic)
FGF3 fibroblast growth factor 3
FGF8 fibroblast growth factor 8 (androgen-induced)
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FLT1 fms-related tyrosine kinase 1
FOXA1 forkhead box A1
FOXA2 forkhead box A2
FOXC2 forkhead box C2
FOXF1 forkhead box F1
FOXH1 forkhead box H1
FOXN4 forkhead box N4
GATA3 GATA binding protein 3
GATA4 GATA binding protein 4
GATA6 GATA binding protein 6
GBX2 gastrulation brain homeobox 2
GDF2 growth differentiation factor 2
GDF7 growth differentiation factor 7
GDNF glial cell derived neurotrophic factor
GJA1 gap junction protein, alpha 1, 43kDa
GLI1 GLI family zinc finger 1
GLI2 GLI family zinc finger 2
GLI3 GLI family zinc finger 3
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPC3 glypican 3
GREM1 gremlin 1, DAN family BMP antagonist
GZF1 GDNF-inducible zinc finger protein 1
HAND1 heart and neural crest derivatives expressed 1
HAND2 heart and neural crest derivatives expressed 2
HES1 hes family bHLH transcription factor 1
HES5 hes family bHLH transcription factor 5
HHEX hematopoietically expressed homeobox
HHIP hedgehog interacting protein
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HNF1B HNF1 homeobox B
HOXA11 homeobox A11
HOXA5 homeobox A5
HOXD11 homeobox D11
HRAS Harvey rat sarcoma viral oncogene homolog
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IFT172 intraflagellar transport 172
IFT52 intraflagellar transport 52
IFT57 intraflagellar transport 57
IGF1 insulin-like growth factor 1 (somatomedin C)
IHH indian hedgehog
ILK integrin-linked kinase
KDR kinase insert domain receptor
KLHL3 kelch-like family member 3
KRAS Kirsten rat sarcoma viral oncogene homolog
LAMA1 laminin, alpha 1
LAMA5 laminin, alpha 5
LBX1 ladybird homeobox 1
LEF1 lymphoid enhancer-binding factor 1
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LHX1 LIM homeobox 1
LRP5 low density lipoprotein receptor-related protein 5
LRP6 low density lipoprotein receptor-related protein 6
MED1 mediator complex subunit 1
MEF2C myocyte enhancer factor 2C
MEGF8 multiple EGF-like-domains 8
MESP1 mesoderm posterior basic helix-loop-helix transcription factor 1
MET MET proto-oncogene, receptor tyrosine kinase
MIB1 mindbomb E3 ubiquitin protein ligase 1
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MKKS McKusick-Kaufman syndrome
MKS1 Meckel syndrome, type 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MSX2 msh homeobox 2
MTSS1 metastasis suppressor 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NCOA3 nuclear receptor coactivator 3
NDRG4 NDRG family member 4
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NKX2-1 NK2 homeobox 1
NKX2-5 NK2 homeobox 5
NKX3-1 NK3 homeobox 1
NODAL nodal growth differentiation factor
NOTCH1 notch 1
NOTCH4 notch 4
NPHP3 nephronophthisis 3 (adolescent)
NPNT nephronectin
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRARP NOTCH-regulated ankyrin repeat protein
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NRP1 neuropilin 1
NTN1 netrin 1
OSR1 odd-skipped related transciption factor 1
OVOL2 ovo-like zinc finger 2
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAX2 paired box 2
PAX8 paired box 8
PBX1 pre-B-cell leukemia homeobox 1
PDPN podoplanin
PGF placental growth factor
PGR progesterone receptor
PHB2 prohibitin 2
PITX2 paired-like homeodomain 2
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKD2 polycystic kidney disease 2 (autosomal dominant)
PLXND1 plexin D1
PML promyelocytic leukemia
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PRKD2 protein kinase D2
PRKX protein kinase, X-linked
PSEN1 presenilin 1
PSPN persephin
PTCH1 patched 1
PXN paxillin
RASIP1 Ras interacting protein 1
RBM15 RNA binding motif protein 15
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RDH10 retinol dehydrogenase 10 (all-trans)
RSPO2 R-spondin 2
RYR2 ryanodine receptor 2 (cardiac)
SALL1 spalt-like transcription factor 1
SCRIB scribbled planar cell polarity protein
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SETDB2 SET domain, bifurcated 2
SFRP1 secreted frizzled-related protein 1
SFRP2 secreted frizzled-related protein 2
SFRP5 secreted frizzled-related protein 5
SHH sonic hedgehog
SIX1 SIX homeobox 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLIT2 slit homolog 2 (Drosophila)
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMO smoothened, frizzled class receptor
SOX10 SRY (sex determining region Y)-box 10
SOX17 SRY (sex determining region Y)-box 17
SOX18 SRY (sex determining region Y)-box 18
SOX2 SRY (sex determining region Y)-box 2
SOX8 SRY (sex determining region Y)-box 8
SOX9 SRY (sex determining region Y)-box 9
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRF serum response factor (c-fos serum response element-binding transcription factor)
STIL SCL/TAL1 interrupting locus
STK4 serine/threonine kinase 4
STRA6 stimulated by retinoic acid 6
SUFU suppressor of fused homolog (Drosophila)
TACSTD2 tumor-associated calcium signal transducer 2
TBX1 T-box 1
TBX20 T-box 20
TBX3 T-box 3
TCF21 transcription factor 21
TEAD2 TEA domain family member 2
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIMELESS timeless circadian clock
TP63 tumor protein p63
TP73 tumor protein p73
TULP3 tubby like protein 3
VANGL2 VANGL planar cell polarity protein 2
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
WNK4 WNK lysine deficient protein kinase 4
WNT1 wingless-type MMTV integration site family, member 1
WNT11 wingless-type MMTV integration site family, member 11
WNT3A wingless-type MMTV integration site family, member 3A
WNT4 wingless-type MMTV integration site family, member 4
WNT5A wingless-type MMTV integration site family, member 5A
WNT6 wingless-type MMTV integration site family, member 6
WNT9B wingless-type MMTV integration site family, member 9B
WT1 Wilms tumor 1
YAP1 Yes-associated protein 1
ZEB1 zinc finger E-box binding homeobox 1
ZIC3 Zic family member 3