tropine-3569 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the tropine-3569 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALOX5 arachidonate 5-lipoxygenase
ALS2CL ALS2 C-terminal like
APOM apolipoprotein M
ARC activity-regulated cytoskeleton-associated protein
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARNT aryl hydrocarbon receptor nuclear translocator
ATAD5 ATPase family, AAA domain containing 5
C10ORF95 chromosome 10 open reading frame 95
C1QB complement component 1, q subcomponent, B chain
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CEP41 centrosomal protein 41kDa
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLTC clathrin, heavy chain (Hc)
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
COL9A3 collagen, type IX, alpha 3
CTIF CBP80/20-dependent translation initiation factor
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DPY19L1P1 DPY19L1 pseudogene 1
DRICH1 aspartate-rich 1
DSCC1 DNA replication and sister chromatid cohesion 1
DUSP1 dual specificity phosphatase 1
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
DYSF dysferlin
E2F5 E2F transcription factor 5, p130-binding
EFNA3 ephrin-A3
EFNB3 ephrin-B3
EML3 echinoderm microtubule associated protein like 3
FAM46C family with sequence similarity 46, member C
FBXO9 F-box protein 9
FGFR1OP FGFR1 oncogene partner
GPER1 G protein-coupled estrogen receptor 1
GSPT1 G1 to S phase transition 1
GSTM2 glutathione S-transferase mu 2 (muscle)
GYG2 glycogenin 2
HLA-C major histocompatibility complex, class I, C
IL11 interleukin 11
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA0754 KIAA0754
KLHL20 kelch-like family member 20
KLHL22 kelch-like family member 22
LAMP1 lysosomal-associated membrane protein 1
LHX6 LIM homeobox 6
LIG3 ligase III, DNA, ATP-dependent
LMAN1 lectin, mannose-binding, 1
LOC100287590 uncharacterized LOC100287590
MAST2 microtubule associated serine/threonine kinase 2
MCAM melanoma cell adhesion molecule
MCC mutated in colorectal cancers
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MMP11 matrix metallopeptidase 11
MMP25 matrix metallopeptidase 25
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYLK myosin light chain kinase
MYOF myoferlin
NF1 neurofibromin 1
NMT1 N-myristoyltransferase 1
NUP88 nucleoporin 88kDa
PHTF2 putative homeodomain transcription factor 2
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PLD3 phospholipase D family, member 3
PMCH pro-melanin-concentrating hormone
PODXL podocalyxin-like
PRND prion protein 2 (dublet)
QSER1 glutamine and serine rich 1
RAB35 RAB35, member RAS oncogene family
RFXAP regulatory factor X-associated protein
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF19B ring finger protein 19B
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
S100A4 S100 calcium binding protein A4
SAYSD1 SAYSVFN motif domain containing 1
SIRT5 sirtuin 5
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SPTAN1 spectrin, alpha, non-erythrocytic 1
SSBP3 single stranded DNA binding protein 3
SSPN sarcospan
SUGP1 SURP and G patch domain containing 1
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TAPBP TAP binding protein (tapasin)
TCP10 t-complex 10
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TM4SF4 transmembrane 4 L six family member 4
TMEM144 transmembrane protein 144
TMPRSS4 transmembrane protease, serine 4
TOX4 TOX high mobility group box family member 4
UBXN1 UBX domain protein 1
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
VPS9D1 VPS9 domain containing 1
ZIC3 Zic family member 3
ZNF407 zinc finger protein 407
ZNF573 zinc finger protein 573
ZNF639 zinc finger protein 639
ZSCAN2 zinc finger and SCAN domain containing 2

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ADGRE5 adhesion G protein-coupled receptor E5
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ATG2A autophagy related 2A
ATP13A2 ATPase type 13A2
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BAHCC1 BAH domain and coiled-coil containing 1
BCL9 B-cell CLL/lymphoma 9
BMP4 bone morphogenetic protein 4
C14ORF93 chromosome 14 open reading frame 93
C1ORF159 chromosome 1 open reading frame 159
CBX8 chromobox homolog 8
CCDC9 coiled-coil domain containing 9
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD82 CD82 molecule
CDK20 cyclin-dependent kinase 20
CHRM3 cholinergic receptor, muscarinic 3
CIDEC cell death-inducing DFFA-like effector c
CISH cytokine inducible SH2-containing protein
CNGB3 cyclic nucleotide gated channel beta 3
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CUEDC1 CUE domain containing 1
DAGLA diacylglycerol lipase, alpha
DGKE diacylglycerol kinase, epsilon 64kDa
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DSCAM Down syndrome cell adhesion molecule
DUSP2 dual specificity phosphatase 2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EXOC6B exocyst complex component 6B
FADS2 fatty acid desaturase 2
FAM198B family with sequence similarity 198, member B
FLT4 fms-related tyrosine kinase 4
GEMIN8 gem (nuclear organelle) associated protein 8
GFPT2 glutamine-fructose-6-phosphate transaminase 2
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H2BJ histone cluster 1, H2bj
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXC8 homeobox C8
INO80D INO80 complex subunit D
IPO8 importin 8
KIAA0319L KIAA0319-like
KIFC1 kinesin family member C1
KPNA5 karyopherin alpha 5 (importin alpha 6)
LAMB3 laminin, beta 3
LOC390998 ribosomal protein L10 pseudogene
LOC729164 hCG1732469
LY6D lymphocyte antigen 6 complex, locus D
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAP1S microtubule-associated protein 1S
MEFV Mediterranean fever
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MTSS1L metastasis suppressor 1-like
MYL5 myosin, light chain 5, regulatory
NLGN1 neuroligin 1
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPIPB15 nuclear pore complex interacting protein family, member B15
NR1H2 nuclear receptor subfamily 1, group H, member 2
NXPH4 neurexophilin 4
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OSMR oncostatin M receptor
PCDHB3 protocadherin beta 3
PDE8B phosphodiesterase 8B
PLEKHA6 pleckstrin homology domain containing, family A member 6
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PRB3 proline-rich protein BstNI subfamily 3
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAB4B RAB4B, member RAS oncogene family
RPAP1 RNA polymerase II associated protein 1
RPL10L ribosomal protein L10-like
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SCML2 sex comb on midleg-like 2 (Drosophila)
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SERGEF secretion regulating guanine nucleotide exchange factor
SH2B3 SH2B adaptor protein 3
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLMO1 slowmo homolog 1 (Drosophila)
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SMR3A submaxillary gland androgen regulated protein 3A
SRD5A3 steroid 5 alpha-reductase 3
STIM1 stromal interaction molecule 1
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAGLN transgelin
TAOK1 TAO kinase 1
TDRD1 tudor domain containing 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TLN1 talin 1
TLR2 toll-like receptor 2
TLR5 toll-like receptor 5
URM1 ubiquitin related modifier 1
USB1 U6 snRNA biogenesis 1
VGF VGF nerve growth factor inducible
ZC3H3 zinc finger CCCH-type containing 3
ZNF286A zinc finger protein 286A
ZNF324 zinc finger protein 324
ZNF606 zinc finger protein 606
ZNF747 zinc finger protein 747