trimethylcolchicinic acid-2802 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

191 genes differentially expressed following the trimethylcolchicinic acid-2802 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ABI3BP ABI family, member 3 (NESH) binding protein
AIRE autoimmune regulator
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARL4C ADP-ribosylation factor-like 4C
ARNT aryl hydrocarbon receptor nuclear translocator
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BTF3P11 basic transcription factor 3 pseudogene 11
C1ORF61 chromosome 1 open reading frame 61
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CACTIN cactin, spliceosome C complex subunit
CD7 CD7 molecule
CDK6 cyclin-dependent kinase 6
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CLEC4M C-type lectin domain family 4, member M
COL1A1 collagen, type I, alpha 1
COMT catechol-O-methyltransferase
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
DCAF4 DDB1 and CUL4 associated factor 4
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNALI1 dynein, axonemal, light intermediate chain 1
DOCK6 dedicator of cytokinesis 6
EFR3B EFR3 homolog B (S. cerevisiae)
FAM46C family with sequence similarity 46, member C
FN1 fibronectin 1
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GADD45G growth arrest and DNA-damage-inducible, gamma
GFER growth factor, augmenter of liver regeneration
GNG3 guanine nucleotide binding protein (G protein), gamma 3
HLA-DMA major histocompatibility complex, class II, DM alpha
HOXB3 homeobox B3
HPX hemopexin
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
IFI35 interferon-induced protein 35
IL23A interleukin 23, alpha subunit p19
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
LAMP1 lysosomal-associated membrane protein 1
LENEP lens epithelial protein
LYRM9 LYR motif containing 9
MAN2A2 mannosidase, alpha, class 2A, member 2
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MTAP methylthioadenosine phosphorylase
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NR2E3 nuclear receptor subfamily 2, group E, member 3
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4
PACS1 phosphofurin acidic cluster sorting protein 1
PALM paralemmin
PAX2 paired box 2
PDE10A phosphodiesterase 10A
PDE4DIP phosphodiesterase 4D interacting protein
PIGR polymeric immunoglobulin receptor
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PML promyelocytic leukemia
POFUT1 protein O-fucosyltransferase 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRAME preferentially expressed antigen in melanoma
PRF1 perforin 1 (pore forming protein)
PSG1 pregnancy specific beta-1-glycoprotein 1
PTRF polymerase I and transcript release factor
PURG purine-rich element binding protein G
PWAR5 Prader Willi/Angelman region RNA 5
RASAL2 RAS protein activator like 2
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
RND1 Rho family GTPase 1
RXRB retinoid X receptor, beta
SARM1 sterile alpha and TIR motif containing 1
SCAPER S-phase cyclin A-associated protein in the ER
SELPLG selectin P ligand
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SNCG synuclein, gamma (breast cancer-specific protein 1)
SPO11 SPO11 meiotic protein covalently bound to DSB
SPX spexin hormone
SSTR4 somatostatin receptor 4
TM4SF1 transmembrane 4 L six family member 1
TMC6 transmembrane channel-like 6
TMEM63A transmembrane protein 63A
TNK2 tyrosine kinase, non-receptor, 2
TRAV8-3 T cell receptor alpha variable 8-3
TRPC6 transient receptor potential cation channel, subfamily C, member 6
UBA6 ubiquitin-like modifier activating enzyme 6
UBE3A ubiquitin protein ligase E3A
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WDR1 WD repeat domain 1
WNT16 wingless-type MMTV integration site family, member 16
ZBTB48 zinc finger and BTB domain containing 48
ZFP36L2 ZFP36 ring finger protein-like 2
ZFP64 ZFP64 zinc finger protein
ZNF205 zinc finger protein 205

decreased expression

Symbol Name
ACSL4 acyl-CoA synthetase long-chain family member 4
AKAP12 A kinase (PRKA) anchor protein 12
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ASPHD1 aspartate beta-hydroxylase domain containing 1
BBC3 BCL2 binding component 3
BBS7 Bardet-Biedl syndrome 7
BCL9 B-cell CLL/lymphoma 9
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC69 coiled-coil domain containing 69
CFL1 cofilin 1 (non-muscle)
CLDN15 claudin 15
COPZ2 coatomer protein complex, subunit zeta 2
CORO2A coronin, actin binding protein, 2A
DCAF13 DDB1 and CUL4 associated factor 13
DESI1 desumoylating isopeptidase 1
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DGAT1 diacylglycerol O-acyltransferase 1
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EDC4 enhancer of mRNA decapping 4
EGLN1 egl-9 family hypoxia-inducible factor 1
ENO2 enolase 2 (gamma, neuronal)
EPHA2 EPH receptor A2
ERCC3 excision repair cross-complementation group 3
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ETAA1 Ewing tumor-associated antigen 1
EXO5 exonuclease 5
FBRS fibrosin
FBXL4 F-box and leucine-rich repeat protein 4
GBAS glioblastoma amplified sequence
GLS2 glutaminase 2 (liver, mitochondrial)
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GOLGA8B golgin A8 family, member B
GPRASP1 G protein-coupled receptor associated sorting protein 1
GSTM2 glutathione S-transferase mu 2 (muscle)
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H1D histone cluster 1, H1d
HIST1H2AJ histone cluster 1, H2aj
HMOX1 heme oxygenase 1
INF2 inverted formin, FH2 and WH2 domain containing
ITPKB inositol-trisphosphate 3-kinase B
KLHL21 kelch-like family member 21
LYPD1 LY6/PLAUR domain containing 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MICALL2 MICAL-like 2
MXD3 MAX dimerization protein 3
MYO1D myosin ID
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEK11 NIMA-related kinase 11
NFE2L3 nuclear factor, erythroid 2-like 3
NKAIN1 Na+/K+ transporting ATPase interacting 1
NPY1R neuropeptide Y receptor Y1
NUBPL nucleotide binding protein-like
OLFML3 olfactomedin-like 3
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PARP16 poly (ADP-ribose) polymerase family, member 16
PC pyruvate carboxylase
PDZRN3 PDZ domain containing ring finger 3
PEX26 peroxisomal biogenesis factor 26
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLD2 phospholipase D2
PLEKHA6 pleckstrin homology domain containing, family A member 6
PRPH peripherin
PRSS22 protease, serine, 22
PTPRE protein tyrosine phosphatase, receptor type, E
RAB33B RAB33B, member RAS oncogene family
RHOBTB2 Rho-related BTB domain containing 2
SCRN3 secernin 3
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SNHG3 small nucleolar RNA host gene 3
SOAT1 sterol O-acyltransferase 1
SPIDR scaffolding protein involved in DNA repair
SPINK4 serine peptidase inhibitor, Kazal type 4
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TMEM62 transmembrane protein 62
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRIM21 tripartite motif containing 21
TTF2 transcription termination factor, RNA polymerase II
TUBA3C tubulin, alpha 3c
ULBP2 UL16 binding protein 2
USB1 U6 snRNA biogenesis 1
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
XK X-linked Kx blood group
ZBED1 zinc finger, BED-type containing 1
ZBTB6 zinc finger and BTB domain containing 6
ZNF165 zinc finger protein 165
ZNF408 zinc finger protein 408
ZNF639 zinc finger protein 639
ZNF696 zinc finger protein 696
ZNF7 zinc finger protein 7
ZNF862 zinc finger protein 862