trifluoperazine-6984 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the trifluoperazine-6984 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ATF3 activating transcription factor 3
BIRC3 baculoviral IAP repeat containing 3
C14ORF132 chromosome 14 open reading frame 132
C16ORF45 chromosome 16 open reading frame 45
CA5B carbonic anhydrase VB, mitochondrial
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CD44 CD44 molecule (Indian blood group)
CD79B CD79b molecule, immunoglobulin-associated beta
CEMIP cell migration inducing protein, hyaluronan binding
CEP162 centrosomal protein 162kDa
CFAP44 cilia and flagella associated protein 44
CGA glycoprotein hormones, alpha polypeptide
CLDN1 claudin 1
CLIP1 CAP-GLY domain containing linker protein 1
CRY2 cryptochrome circadian clock 2
DDIT4 DNA-damage-inducible transcript 4
EFNA3 ephrin-A3
EGR1 early growth response 1
ELOVL4 ELOVL fatty acid elongase 4
EMP1 epithelial membrane protein 1
F11R F11 receptor
FAM169A family with sequence similarity 169, member A
FGD1 FYVE, RhoGEF and PH domain containing 1
FHL1 four and a half LIM domains 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FSHB follicle stimulating hormone, beta polypeptide
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GEM GTP binding protein overexpressed in skeletal muscle
GMEB1 glucocorticoid modulatory element binding protein 1
HBS1L HBS1-like translational GTPase
HDLBP high density lipoprotein binding protein
HFE hemochromatosis
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HPS1 Hermansky-Pudlak syndrome 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IGHMBP2 immunoglobulin mu binding protein 2
IL4R interleukin 4 receptor
INSIG1 insulin induced gene 1
IQCE IQ motif containing E
IRS2 insulin receptor substrate 2
ISG20 interferon stimulated exonuclease gene 20kDa
JAG1 jagged 1
JUN jun proto-oncogene
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KLF7 Kruppel-like factor 7 (ubiquitous)
KLHL24 kelch-like family member 24
LMAN1 lectin, mannose-binding, 1
LOC390998 ribosomal protein L10 pseudogene
LYST lysosomal trafficking regulator
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MMP3 matrix metallopeptidase 3
MUC1 mucin 1, cell surface associated
MYO1F myosin IF
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NOP16 NOP16 nucleolar protein
NR6A1 nuclear receptor subfamily 6, group A, member 1
NXPE3 neurexophilin and PC-esterase domain family, member 3
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2
ORC5 origin recognition complex, subunit 5
PAPPA2 pappalysin 2
PAX9 paired box 9
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPRE protein tyrosine phosphatase, receptor type, E
PTRF polymerase I and transcript release factor
RAD51B RAD51 paralog B
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RGS12 regulator of G-protein signaling 12
SAMD9 sterile alpha motif domain containing 9
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SOS2 son of sevenless homolog 2 (Drosophila)
SPTAN1 spectrin, alpha, non-erythrocytic 1
SQSTM1 sequestosome 1
STK4 serine/threonine kinase 4
TECTA tectorin alpha
TFPI2 tissue factor pathway inhibitor 2
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TRIM2 tripartite motif containing 2
UBOX5 U-box domain containing 5
UPK3B uroplakin 3B
USB1 U6 snRNA biogenesis 1
WIPI1 WD repeat domain, phosphoinositide interacting 1
WWP2 WW domain containing E3 ubiquitin protein ligase 2
ZFP64 ZFP64 zinc finger protein
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF16 zinc finger protein 16
ZNF419 zinc finger protein 419
ZNF74 zinc finger protein 74
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ADCY6 adenylate cyclase 6
AEN apoptosis enhancing nuclease
AKIP1 A kinase (PRKA) interacting protein 1
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ARHGAP10 Rho GTPase activating protein 10
ARHGAP5 Rho GTPase activating protein 5
AXIN1 axin 1
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BBS1 Bardet-Biedl syndrome 1
BBS7 Bardet-Biedl syndrome 7
BCL2L2 BCL2-like 2
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C5 complement component 5
C5ORF45 chromosome 5 open reading frame 45
C6ORF47 chromosome 6 open reading frame 47
CASKIN2 CASK interacting protein 2
CCDC15 coiled-coil domain containing 15
CENPE centromere protein E, 312kDa
CEP131 centrosomal protein 131kDa
CHMP6 charged multivesicular body protein 6
CLEC16A C-type lectin domain family 16, member A
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLSPN claspin
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CPPED1 calcineurin-like phosphoesterase domain containing 1
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DEAF1 DEAF1 transcription factor
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DNA2 DNA replication helicase/nuclease 2
DNAL4 dynein, axonemal, light chain 4
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPHA2 EPH receptor A2
ERO1L ERO1-like (S. cerevisiae)
EXTL2 exostosin-like glycosyltransferase 2
FAM86C1 family with sequence similarity 86, member C1
FANCC Fanconi anemia, complementation group C
FMO4 flavin containing monooxygenase 4
FOXJ2 forkhead box J2
FPGS folylpolyglutamate synthase
GDAP2 ganglioside induced differentiation associated protein 2
GHR growth hormone receptor
GLB1L2 galactosidase, beta 1-like 2
GLCE glucuronic acid epimerase
GPR19 G protein-coupled receptor 19
GYS1 glycogen synthase 1 (muscle)
HAUS6 HAUS augmin-like complex, subunit 6
IFT140 intraflagellar transport 140
KAT2A K(lysine) acetyltransferase 2A
KIAA0556 KIAA0556
KRBOX4 KRAB box domain containing 4
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LINC00339 long intergenic non-protein coding RNA 339
LRP3 low density lipoprotein receptor-related protein 3
LZTR1 leucine-zipper-like transcription regulator 1
MYO1D myosin ID
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OTUD3 OTU deubiquitinase 3
PCTP phosphatidylcholine transfer protein
PHACTR4 phosphatase and actin regulator 4
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PRKCD protein kinase C, delta
RBM41 RNA binding motif protein 41
RECQL4 RecQ protein-like 4
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RIPPLY3 ripply transcriptional repressor 3
RNF25 ring finger protein 25
SCAMP5 secretory carrier membrane protein 5
SH2B3 SH2B adaptor protein 3
SH3BGR SH3 domain binding glutamate-rich protein
SLC46A3 solute carrier family 46, member 3
SOX12 SRY (sex determining region Y)-box 12
SPRYD7 SPRY domain containing 7
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STK25 serine/threonine kinase 25
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TKFC triokinase/FMN cyclase
TMEM110 transmembrane protein 110
TRAF2 TNF receptor-associated factor 2
TRAF5 TNF receptor-associated factor 5
TRIM25 tripartite motif containing 25
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSPYL2 TSPY-like 2
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
WDR62 WD repeat domain 62
XAB2 XPA binding protein 2
XPC xeroderma pigmentosum, complementation group C
XYLT2 xylosyltransferase II
ZC3H3 zinc finger CCCH-type containing 3
ZDHHC18 zinc finger, DHHC-type containing 18
ZFP30 ZFP30 zinc finger protein
ZNF142 zinc finger protein 142
ZNF408 zinc finger protein 408
ZNF813 zinc finger protein 813