trichostatin A-873 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the trichostatin A-873 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
AHNAK2 AHNAK nucleoprotein 2
AKAP12 A kinase (PRKA) anchor protein 12
ALDOC aldolase C, fructose-bisphosphate
ARMCX2 armadillo repeat containing, X-linked 2
BAIAP2 BAI1-associated protein 2
BAIAP3 BAI1-associated protein 3
CALCOCO1 calcium binding and coiled-coil domain 1
CCDC28A coiled-coil domain containing 28A
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CLGN calmegin
CORO1A coronin, actin binding protein, 1A
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSRP2 cysteine and glycine-rich protein 2
CXADR coxsackie virus and adenovirus receptor
CYLD cylindromatosis (turban tumor syndrome)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLX2 distal-less homeobox 2
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DPYSL4 dihydropyrimidinase-like 4
EAF2 ELL associated factor 2
EFNA3 ephrin-A3
EPOR erythropoietin receptor
FANCE Fanconi anemia, complementation group E
FKBP1B FK506 binding protein 1B, 12.6 kDa
FOS FBJ murine osteosarcoma viral oncogene homolog
FSCN1 fascin actin-bundling protein 1
GEM GTP binding protein overexpressed in skeletal muscle
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GLRX glutaredoxin (thioltransferase)
GLS glutaminase
GRK5 G protein-coupled receptor kinase 5
GTF2B general transcription factor IIB
HBEGF heparin-binding EGF-like growth factor
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HOXA1 homeobox A1
HSPA2 heat shock 70kDa protein 2
ITM2C integral membrane protein 2C
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KIAA0355 KIAA0355
KIAA0513 KIAA0513
KIF13B kinesin family member 13B
KIF21B kinesin family member 21B
LIMA1 LIM domain and actin binding 1
LINC00341 long intergenic non-protein coding RNA 341
MAP1A microtubule-associated protein 1A
MAP1B microtubule-associated protein 1B
MAPRE2 microtubule-associated protein, RP/EB family, member 2
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NPC1 Niemann-Pick disease, type C1
PADI3 peptidyl arginine deiminase, type III
PCDH9 protocadherin 9
PDE4DIP phosphodiesterase 4D interacting protein
PER1 period circadian clock 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PRPH peripherin
PTRF polymerase I and transcript release factor
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
RIPK4 receptor-interacting serine-threonine kinase 4
RND1 Rho family GTPase 1
RPL3L ribosomal protein L3-like
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RTN2 reticulon 2
RUNDC3B RUN domain containing 3B
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPP1 selenoprotein P, plasma, 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SNAI2 snail family zinc finger 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STARD5 StAR-related lipid transfer (START) domain containing 5
STK17A serine/threonine kinase 17a
STON1 stonin 1
SYBU syntabulin (syntaxin-interacting)
TBXA2R thromboxane A2 receptor
THEMIS2 thymocyte selection associated family member 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
ULBP2 UL16 binding protein 2
WDR19 WD repeat domain 19
WDR47 WD repeat domain 47
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZBTB18 zinc finger and BTB domain containing 18
ZCCHC24 zinc finger, CCHC domain containing 24
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF204P zinc finger protein 204, pseudogene

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADNP activity-dependent neuroprotector homeobox
AMIGO2 adhesion molecule with Ig-like domain 2
AMOTL2 angiomotin like 2
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARMCX5 armadillo repeat containing, X-linked 5
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ASTE1 asteroid homolog 1 (Drosophila)
BANP BTG3 associated nuclear protein
BCAR3 breast cancer anti-estrogen resistance 3
BRD1 bromodomain containing 1
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C1ORF216 chromosome 1 open reading frame 216
C7ORF49 chromosome 7 open reading frame 49
C9ORF40 chromosome 9 open reading frame 40
C9ORF91 chromosome 9 open reading frame 91
CASD1 CAS1 domain containing 1
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CLK1 CDC-like kinase 1
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CUL1 cullin 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP4 dual specificity phosphatase 4
EFNA1 ephrin-A1
EGR3 early growth response 3
ESRP2 epithelial splicing regulatory protein 2
FAM57A family with sequence similarity 57, member A
FJX1 four jointed box 1 (Drosophila)
FOXA1 forkhead box A1
FOXC1 forkhead box C1
FOXD1 forkhead box D1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GABPB1 GA binding protein transcription factor, beta subunit 1
GATA3 GATA binding protein 3
GMEB2 glucocorticoid modulatory element binding protein 2
GTF2IRD1 GTF2I repeat domain containing 1
HOXC11 homeobox C11
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
IRX5 iroquois homeobox 5
JADE1 jade family PHD finger 1
KEAP1 kelch-like ECH-associated protein 1
KIAA0753 KIAA0753
LHFPL2 lipoma HMGIC fusion partner-like 2
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
MEPCE methylphosphate capping enzyme
MSL1 male-specific lethal 1 homolog (Drosophila)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NPY1R neuropeptide Y receptor Y1
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRIP1 nuclear receptor interacting protein 1
NUAK1 NUAK family, SNF1-like kinase, 1
PAPD7 PAP associated domain containing 7
PHIP pleckstrin homology domain interacting protein
POGK pogo transposable element with KRAB domain
PPP1R8 protein phosphatase 1, regulatory subunit 8
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRNP prion protein
PRR15L proline rich 15-like
PTBP2 polypyrimidine tract binding protein 2
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM23 RNA binding motif protein 23
REV1 REV1, polymerase (DNA directed)
RHOBTB1 Rho-related BTB domain containing 1
SCAF8 SR-related CTD-associated factor 8
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SETD1B SET domain containing 1B
SFMBT1 Scm-like with four mbt domains 1
SMAD7 SMAD family member 7
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMG9 SMG9 nonsense mediated mRNA decay factor
SPIN1 spindlin 1
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SRSF4 serine/arginine-rich splicing factor 4
STBD1 starch binding domain 1
STC2 stanniocalcin 2
TMEM30B transmembrane protein 30B
TOE1 target of EGR1, member 1 (nuclear)
TRAF5 TNF receptor-associated factor 5
TRIB1 tribbles pseudokinase 1
TRIB3 tribbles pseudokinase 3
TRIM16 tripartite motif containing 16
TRPS1 trichorhinophalangeal syndrome I
TSKU tsukushi, small leucine rich proteoglycan
XBP1 X-box binding protein 1
ZC3H4 zinc finger CCCH-type containing 4
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1
ZNF239 zinc finger protein 239
ZNF254 zinc finger protein 254
ZNF33B zinc finger protein 33B
ZNF692 zinc finger protein 692