trichostatin A-7555 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the trichostatin A-7555 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ADRB2 adrenoceptor beta 2, surface
ANGPTL4 angiopoietin-like 4
AQP3 aquaporin 3 (Gill blood group)
ARG2 arginase 2
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASMTL acetylserotonin O-methyltransferase-like
ATP7A ATPase, Cu++ transporting, alpha polypeptide
AVPI1 arginine vasopressin-induced 1
BAIAP2 BAI1-associated protein 2
BAMBI BMP and activin membrane-bound inhibitor
C8ORF60 chromosome 8 open reading frame 60
CCNA1 cyclin A1
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLU clusterin
CORO1A coronin, actin binding protein, 1A
CPM carboxypeptidase M
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTGF connective tissue growth factor
CTH cystathionine gamma-lyase
CYR61 cysteine-rich, angiogenic inducer, 61
DDIT4 DNA-damage-inducible transcript 4
DENND3 DENN/MADD domain containing 3
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
EPPK1 epiplakin 1
FABP4 fatty acid binding protein 4, adipocyte
FAM69A family with sequence similarity 69, member A
GADD45B growth arrest and DNA-damage-inducible, beta
GEM GTP binding protein overexpressed in skeletal muscle
GLRX glutaredoxin (thioltransferase)
GLS glutaminase
GMCL1 germ cell-less, spermatogenesis associated 1
GPRC5A G protein-coupled receptor, class C, group 5, member A
GTF2B general transcription factor IIB
GUCY1B3 guanylate cyclase 1, soluble, beta 3
H1FX H1 histone family, member X
HBEGF heparin-binding EGF-like growth factor
HIST1H2BG histone cluster 1, H2bg
HOXA1 homeobox A1
HSPA2 heat shock 70kDa protein 2
IL11 interleukin 11
INSIG1 insulin induced gene 1
JUNB jun B proto-oncogene
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIF5C kinesin family member 5C
LIMA1 LIM domain and actin binding 1
LMCD1 LIM and cysteine-rich domains 1
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAST3 microtubule associated serine/threonine kinase 3
MBNL2 muscleblind-like splicing regulator 2
MLF1 myeloid leukemia factor 1
MMP1 matrix metallopeptidase 1
MOSPD2 motile sperm domain containing 2
MPP1 membrane protein, palmitoylated 1, 55kDa
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NEU1 sialidase 1 (lysosomal sialidase)
NMT2 N-myristoyltransferase 2
NPC1 Niemann-Pick disease, type C1
OASL 2'-5'-oligoadenylate synthetase-like
PHKG2 phosphorylase kinase, gamma 2 (testis)
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB8B RAB8B, member RAS oncogene family
RAI2 retinoic acid induced 2
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS4 regulator of G-protein signaling 4
RHOB ras homolog family member B
RSRP1 arginine/serine-rich protein 1
RTN2 reticulon 2
SAT1 spermidine/spermine N1-acetyltransferase 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SREBF1 sterol regulatory element binding transcription factor 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STC1 stanniocalcin 1
STOM stomatin
STX5 syntaxin 5
SYT1 synaptotagmin I
SYT11 synaptotagmin XI
SYTL2 synaptotagmin-like 2
TAOK3 TAO kinase 3
TBPL1 TBP-like 1
TJP3 tight junction protein 3
TMEM47 transmembrane protein 47
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TUBB2B tubulin, beta 2B class IIb
TUFT1 tuftelin 1
ZFP36 ZFP36 ring finger protein
ZNF324 zinc finger protein 324

decreased expression

Symbol Name
ADNP activity-dependent neuroprotector homeobox
AKAP8 A kinase (PRKA) anchor protein 8
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARMC6 armadillo repeat containing 6
ARSJ arylsulfatase family, member J
BCAR3 breast cancer anti-estrogen resistance 3
BHLHE41 basic helix-loop-helix family, member e41
CASD1 CAS1 domain containing 1
CLCN6 chloride channel, voltage-sensitive 6
COG7 component of oligomeric golgi complex 7
COIL coilin
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CUL1 cullin 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DENND4B DENN/MADD domain containing 4B
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
FAM57A family with sequence similarity 57, member A
FBXL15 F-box and leucine-rich repeat protein 15
FJX1 four jointed box 1 (Drosophila)
FOSL1 FOS-like antigen 1
FOXA1 forkhead box A1
FST follistatin
GRPR gastrin-releasing peptide receptor
GTF2IRD1 GTF2I repeat domain containing 1
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
H2AFY2 H2A histone family, member Y2
HAS2 hyaluronan synthase 2
HMGA2 high mobility group AT-hook 2
HOXA10 homeobox A10
INHBB inhibin, beta B
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
ITPKB inositol-trisphosphate 3-kinase B
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KEAP1 kelch-like ECH-associated protein 1
LIF leukemia inhibitory factor
LMNB1 lamin B1
LPAR1 lysophosphatidic acid receptor 1
MAGEA6 melanoma antigen family A6
MED24 mediator complex subunit 24
MEPCE methylphosphate capping enzyme
METTL21B methyltransferase like 21B
METTL4 methyltransferase like 4
MID1IP1 MID1 interacting protein 1
MSL2 male-specific lethal 2 homolog (Drosophila)
MTPAP mitochondrial poly(A) polymerase
MYD88 myeloid differentiation primary response 88
NARFL nuclear prelamin A recognition factor-like
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NLRX1 NLR family member X1
NME6 NME/NM23 nucleoside diphosphate kinase 6
NRIP1 nuclear receptor interacting protein 1
NUBP1 nucleotide binding protein 1
OARD1 O-acyl-ADP-ribose deacylase 1
PAGR1 PAXIP1 associated glutamate-rich protein 1
PEF1 penta-EF-hand domain containing 1
PLAU plasminogen activator, urokinase
PPAP2B phosphatidic acid phosphatase type 2B
PRKX protein kinase, X-linked
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PTGFR prostaglandin F receptor (FP)
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RBM4B RNA binding motif protein 4B
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIN2 Ras and Rab interactor 2
RNF220 ring finger protein 220
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SCO2 SCO2 cytochrome c oxidase assembly protein
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SETD1B SET domain containing 1B
SFMBT1 Scm-like with four mbt domains 1
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC35F2 solute carrier family 35, member F2
SMAGP small cell adhesion glycoprotein
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMYD5 SMYD family member 5
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5)
SNUPN snurportin 1
SNX15 sorting nexin 15
SRSF4 serine/arginine-rich splicing factor 4
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TRIB3 tribbles pseudokinase 3
TRIM13 tripartite motif containing 13
TRIM8 tripartite motif containing 8
TSSC4 tumor suppressing subtransferable candidate 4
TUBGCP5 tubulin, gamma complex associated protein 5
UBL4A ubiquitin-like 4A
UBTF upstream binding transcription factor, RNA polymerase I
USP21 ubiquitin specific peptidase 21
VEGFC vascular endothelial growth factor C
WBSCR16 Williams-Beuren syndrome chromosome region 16
ZC3H4 zinc finger CCCH-type containing 4
ZMYM3 zinc finger, MYM-type 3
ZNF16 zinc finger protein 16
ZNF232 zinc finger protein 232
ZNF32 zinc finger protein 32
ZNF33B zinc finger protein 33B
ZNF692 zinc finger protein 692
ZZZ3 zinc finger, ZZ-type containing 3