trichostatin A-7550 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the trichostatin A-7550 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADD3 adducin 3 (gamma)
ADK adenosine kinase
AHNAK2 AHNAK nucleoprotein 2
AHR aryl hydrocarbon receptor
ALDOC aldolase C, fructose-bisphosphate
ARHGAP29 Rho GTPase activating protein 29
ATG2A autophagy related 2A
BAIAP3 BAI1-associated protein 3
C14ORF132 chromosome 14 open reading frame 132
CCDC28A coiled-coil domain containing 28A
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CORO1A coronin, actin binding protein, 1A
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSRP2 cysteine and glycine-rich protein 2
CTSV cathepsin V
CYB5R1 cytochrome b5 reductase 1
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DEGS1 delta(4)-desaturase, sphingolipid 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DPYSL4 dihydropyrimidinase-like 4
EFNB3 ephrin-B3
FN1 fibronectin 1
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GCDH glutaryl-CoA dehydrogenase
GCHFR GTP cyclohydrolase I feedback regulator
GEM GTP binding protein overexpressed in skeletal muscle
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GLCE glucuronic acid epimerase
GLRX glutaredoxin (thioltransferase)
GLS glutaminase
GRK5 G protein-coupled receptor kinase 5
GTF2B general transcription factor IIB
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HSPA2 heat shock 70kDa protein 2
INSIG1 insulin induced gene 1
IRF6 interferon regulatory factor 6
KIDINS220 kinase D-interacting substrate, 220kDa
KIF13B kinesin family member 13B
KIF5C kinesin family member 5C
KLHL24 kelch-like family member 24
KLHL26 kelch-like family member 26
LIMA1 LIM domain and actin binding 1
LPIN1 lipin 1
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAP2K3 mitogen-activated protein kinase kinase 3
MAST3 microtubule associated serine/threonine kinase 3
MLF1 myeloid leukemia factor 1
MMD monocyte to macrophage differentiation-associated
MXI1 MAX interactor 1, dimerization protein
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NEK1 NIMA-related kinase 1
NPC1 Niemann-Pick disease, type C1
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NXN nucleoredoxin
PADI3 peptidyl arginine deiminase, type III
PCDH9 protocadherin 9
PDE4DIP phosphodiesterase 4D interacting protein
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRPH peripherin
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB40B RAB40B, member RAS oncogene family
RANBP10 RAN binding protein 10
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
RPL3L ribosomal protein L3-like
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RUNDC3B RUN domain containing 3B
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPP1 selenoprotein P, plasma, 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
SOAT1 sterol O-acyltransferase 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STXBP1 syntaxin binding protein 1
SYT11 synaptotagmin XI
TMSB15A thymosin beta 15a
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TRIM2 tripartite motif containing 2
TUBB2A tubulin, beta 2A class IIa
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
WDR19 WD repeat domain 19
WDR47 WD repeat domain 47
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZCCHC24 zinc finger, CCHC domain containing 24
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF204P zinc finger protein 204, pseudogene

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ACVR2B activin A receptor, type IIB
ADNP activity-dependent neuroprotector homeobox
AKAP8 A kinase (PRKA) anchor protein 8
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARMC6 armadillo repeat containing 6
BCAR3 breast cancer anti-estrogen resistance 3
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C11ORF68 chromosome 11 open reading frame 68
C1ORF35 chromosome 1 open reading frame 35
C7ORF49 chromosome 7 open reading frame 49
CAPN15 calpain 15
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CBR3 carbonyl reductase 3
CCDC94 coiled-coil domain containing 94
CCND1 cyclin D1
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CLDN4 claudin 4
CLK4 CDC-like kinase 4
COIL coilin
CPPED1 calcineurin-like phosphoesterase domain containing 1
CTCF CCCTC-binding factor (zinc finger protein)
CUL1 cullin 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DBR1 debranching RNA lariats 1
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DKK1 dickkopf WNT signaling pathway inhibitor 1
EFNA1 ephrin-A1
EGR3 early growth response 3
ESRP2 epithelial splicing regulatory protein 2
ETAA1 Ewing tumor-associated antigen 1
EXOSC10 exosome component 10
FAM57A family with sequence similarity 57, member A
FBRS fibrosin
FJX1 four jointed box 1 (Drosophila)
FOXA1 forkhead box A1
FOXC1 forkhead box C1
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GATA3 GATA binding protein 3
GMEB2 glucocorticoid modulatory element binding protein 2
GPRC5C G protein-coupled receptor, class C, group 5, member C
GRWD1 glutamate-rich WD repeat containing 1
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
IFT140 intraflagellar transport 140
IL4R interleukin 4 receptor
INHBB inhibin, beta B
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IRS1 insulin receptor substrate 1
IRX5 iroquois homeobox 5
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
JMJD1C jumonji domain containing 1C
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KCTD15 potassium channel tetramerization domain containing 15
KEAP1 kelch-like ECH-associated protein 1
LMNB1 lamin B1
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
MATK megakaryocyte-associated tyrosine kinase
MEPCE methylphosphate capping enzyme
MSL1 male-specific lethal 1 homolog (Drosophila)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NRIP1 nuclear receptor interacting protein 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PHLDA3 pleckstrin homology-like domain, family A, member 3
POGK pogo transposable element with KRAB domain
POLR3B polymerase (RNA) III (DNA directed) polypeptide B
PRCC papillary renal cell carcinoma (translocation-associated)
PRR15L proline rich 15-like
PRSS22 protease, serine, 22
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMAD7 SMAD family member 7
SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12)
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SRSF4 serine/arginine-rich splicing factor 4
STC2 stanniocalcin 2
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TGIF1 TGFB-induced factor homeobox 1
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TOE1 target of EGR1, member 1 (nuclear)
TOR3A torsin family 3, member A
TRIB3 tribbles pseudokinase 3
TRIM8 tripartite motif containing 8
TRPS1 trichorhinophalangeal syndrome I
TSKU tsukushi, small leucine rich proteoglycan
UBXN8 UBX domain protein 8
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
XBP1 X-box binding protein 1
ZC3H4 zinc finger CCCH-type containing 4
ZFHX3 zinc finger homeobox 3
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1
ZNF444 zinc finger protein 444
ZNF672 zinc finger protein 672
ZNF692 zinc finger protein 692