trichostatin A-7503 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the trichostatin A-7503 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ADRB2 adrenoceptor beta 2, surface
AIM1L absent in melanoma 1-like
AKAP13 A kinase (PRKA) anchor protein 13
ALAD aminolevulinate dehydratase
ANGPTL4 angiopoietin-like 4
AQP3 aquaporin 3 (Gill blood group)
ARC activity-regulated cytoskeleton-associated protein
ARG2 arginase 2
ASMTL acetylserotonin O-methyltransferase-like
AVPI1 arginine vasopressin-induced 1
BAIAP2 BAI1-associated protein 2
BAIAP3 BAI1-associated protein 3
BCL2L11 BCL2-like 11 (apoptosis facilitator)
C18ORF8 chromosome 18 open reading frame 8
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CLIC3 chloride intracellular channel 3
COPE coatomer protein complex, subunit epsilon
CORO1A coronin, actin binding protein, 1A
CPA4 carboxypeptidase A4
CPM carboxypeptidase M
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSPP1 centrosome and spindle pole associated protein 1
CTGF connective tissue growth factor
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DDIT4 DNA-damage-inducible transcript 4
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DENND3 DENN/MADD domain containing 3
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLX4 distal-less homeobox 4
DPYSL4 dihydropyrimidinase-like 4
DUSP1 dual specificity phosphatase 1
EFNA3 ephrin-A3
ELOVL4 ELOVL fatty acid elongase 4
EPHB2 EPH receptor B2
EPPK1 epiplakin 1
FABP4 fatty acid binding protein 4, adipocyte
FADS3 fatty acid desaturase 3
FAM102A family with sequence similarity 102, member A
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GLCE glucuronic acid epimerase
GPRC5A G protein-coupled receptor, class C, group 5, member A
H1FX H1 histone family, member X
IL11 interleukin 11
INSIG1 insulin induced gene 1
IRF6 interferon regulatory factor 6
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
JARID2 jumonji, AT rich interactive domain 2
KCTD17 potassium channel tetramerization domain containing 17
KIF5C kinesin family member 5C
LAMC2 laminin, gamma 2
LMCD1 LIM and cysteine-rich domains 1
LTB4R leukotriene B4 receptor
LYPD3 LY6/PLAUR domain containing 3
MAPT microtubule-associated protein tau
MARK4 MAP/microtubule affinity-regulating kinase 4
MICA MHC class I polypeptide-related sequence A
MKL1 megakaryoblastic leukemia (translocation) 1
MMP1 matrix metallopeptidase 1
MMP15 matrix metallopeptidase 15 (membrane-inserted)
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NR4A1 nuclear receptor subfamily 4, group A, member 1
OASL 2'-5'-oligoadenylate synthetase-like
ONECUT2 one cut homeobox 2
PCDH9 protocadherin 9
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDE4DIP phosphodiesterase 4D interacting protein
PHKG2 phosphorylase kinase, gamma 2 (testis)
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB31 RAB31, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RAD9A RAD9 homolog A (S. pombe)
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RNF24 ring finger protein 24
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SQLE squalene epoxidase
SREBF1 sterol regulatory element binding transcription factor 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAT1 signal transducer and activator of transcription 1, 91kDa
STC1 stanniocalcin 1
STOM stomatin
SYT11 synaptotagmin XI
TAGLN3 transgelin 3
TJP3 tight junction protein 3
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRAFD1 TRAF-type zinc finger domain containing 1
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb
TUFT1 tuftelin 1
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
ZNF574 zinc finger protein 574

decreased expression

Symbol Name
ADNP activity-dependent neuroprotector homeobox
ADORA2B adenosine A2b receptor
APIP APAF1 interacting protein
ARHGAP5 Rho GTPase activating protein 5
ARMCX5 armadillo repeat containing, X-linked 5
BAG2 BCL2-associated athanogene 2
BCAR3 breast cancer anti-estrogen resistance 3
CDC7 cell division cycle 7
CTCF CCCTC-binding factor (zinc finger protein)
CUL1 cullin 1
CUTC cutC copper transporter
DCTN4 dynactin 4 (p62)
DEPDC1 DEP domain containing 1
DUSP4 dual specificity phosphatase 4
E2F8 E2F transcription factor 8
ERBB2IP erbb2 interacting protein
ESRP1 epithelial splicing regulatory protein 1
FAM206A family with sequence similarity 206, member A
FAM60A family with sequence similarity 60, member A
FOSL1 FOS-like antigen 1
FOXA1 forkhead box A1
FST follistatin
FZD6 frizzled class receptor 6
FZD8 frizzled class receptor 8
GBX2 gastrulation brain homeobox 2
GIN1 gypsy retrotransposon integrase 1
GPR87 G protein-coupled receptor 87
GRAMD3 GRAM domain containing 3
GRPR gastrin-releasing peptide receptor
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HAS2 hyaluronan synthase 2
HMGA2 high mobility group AT-hook 2
HMGB2 high mobility group box 2
HMGB3 high mobility group box 3
HNRNPF heterogeneous nuclear ribonucleoprotein F
INHBB inhibin, beta B
ISOC1 isochorismatase domain containing 1
KBTBD2 kelch repeat and BTB (POZ) domain containing 2
KCTD3 potassium channel tetramerization domain containing 3
KEAP1 kelch-like ECH-associated protein 1
LIF leukemia inhibitory factor
LIPT1 lipoyltransferase 1
LMNB1 lamin B1
LRIF1 ligand dependent nuclear receptor interacting factor 1
MEPCE methylphosphate capping enzyme
MPDU1 mannose-P-dolichol utilization defect 1
MSL2 male-specific lethal 2 homolog (Drosophila)
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NAE1 NEDD8 activating enzyme E1 subunit 1
NCOA6 nuclear receptor coactivator 6
NFE2L2 nuclear factor, erythroid 2-like 2
NME6 NME/NM23 nucleoside diphosphate kinase 6
NR1D2 nuclear receptor subfamily 1, group D, member 2
NRIP1 nuclear receptor interacting protein 1
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PARP4 poly (ADP-ribose) polymerase family, member 4
PBK PDZ binding kinase
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
PCNXL4 pecanex-like 4 (Drosophila)
PEX2 peroxisomal biogenesis factor 2
PLK1 polo-like kinase 1
POGK pogo transposable element with KRAB domain
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
PPP1R8 protein phosphatase 1, regulatory subunit 8
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1
PSAT1 phosphoserine aminotransferase 1
PTPN9 protein tyrosine phosphatase, non-receptor type 9
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RAD51AP1 RAD51 associated protein 1
RBM7 RNA binding motif protein 7
RIN2 Ras and Rab interactor 2
SCAF8 SR-related CTD-associated factor 8
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SETD6 SET domain containing 6
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC35F2 solute carrier family 35, member F2
SMAGP small cell adhesion glycoprotein
SNX5 sorting nexin 5
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SRSF4 serine/arginine-rich splicing factor 4
SRSF8 serine/arginine-rich splicing factor 8
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TMEM168 transmembrane protein 168
TMEM230 transmembrane protein 230
TMPO thymopoietin
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TRIB3 tribbles pseudokinase 3
TRIM13 tripartite motif containing 13
VEGFC vascular endothelial growth factor C
XBP1 X-box binding protein 1
YAF2 YY1 associated factor 2
YIPF5 Yip1 domain family, member 5
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
ZC3H4 zinc finger CCCH-type containing 4
ZC3H7A zinc finger CCCH-type containing 7A
ZNF165 zinc finger protein 165
ZNF32 zinc finger protein 32
ZNF532 zinc finger protein 532