trichostatin A-7499 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the trichostatin A-7499 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACSBG1 acyl-CoA synthetase bubblegum family member 1
AHNAK2 AHNAK nucleoprotein 2
ALDOC aldolase C, fructose-bisphosphate
ANGPTL4 angiopoietin-like 4
APLP1 amyloid beta (A4) precursor-like protein 1
ARL4C ADP-ribosylation factor-like 4C
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATF7IP2 activating transcription factor 7 interacting protein 2
BAIAP2 BAI1-associated protein 2
BAIAP3 BAI1-associated protein 3
BMP7 bone morphogenetic protein 7
C8ORF60 chromosome 8 open reading frame 60
CDH15 cadherin 15, type 1, M-cadherin (myotubule)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CLMN calmin (calponin-like, transmembrane)
CORO1A coronin, actin binding protein, 1A
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CXADR coxsackie virus and adenovirus receptor
CYLD cylindromatosis (turban tumor syndrome)
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DENND3 DENN/MADD domain containing 3
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLX2 distal-less homeobox 2
DPYSL4 dihydropyrimidinase-like 4
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFNB3 ephrin-B3
ELOVL4 ELOVL fatty acid elongase 4
ETV5 ets variant 5
FKBP1B FK506 binding protein 1B, 12.6 kDa
FLRT3 fibronectin leucine rich transmembrane protein 3
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GEM GTP binding protein overexpressed in skeletal muscle
GLDC glycine dehydrogenase (decarboxylating)
GLRX glutaredoxin (thioltransferase)
GLS glutaminase
GRK5 G protein-coupled receptor kinase 5
H1F0 H1 histone family, member 0
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HMHA1 histocompatibility (minor) HA-1
HYAL1 hyaluronoglucosaminidase 1
IRF7 interferon regulatory factor 7
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JAKMIP2 janus kinase and microtubule interacting protein 2
KANK3 KN motif and ankyrin repeat domains 3
KIAA0513 KIAA0513
KIF13B kinesin family member 13B
KIF5C kinesin family member 5C
LIMA1 LIM domain and actin binding 1
LTB4R leukotriene B4 receptor
LZTFL1 leucine zipper transcription factor-like 1
MAP1A microtubule-associated protein 1A
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MCOLN1 mucolipin 1
MUC3B mucin 3B, cell surface associated
NPC1 Niemann-Pick disease, type C1
NXN nucleoredoxin
PADI3 peptidyl arginine deiminase, type III
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDH9 protocadherin 9
PDE4DIP phosphodiesterase 4D interacting protein
PER1 period circadian clock 1
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PLA2G15 phospholipase A2, group XV
PLLP plasmolipin
PMEL premelanosome protein
PRPH peripherin
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PTRF polymerase I and transcript release factor
RAB3B RAB3B, member RAS oncogene family
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
RPL3L ribosomal protein L3-like
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RUNDC3B RUN domain containing 3B
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPP1 selenoprotein P, plasma, 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SIRT4 sirtuin 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
STON1 stonin 1
SUN1 Sad1 and UNC84 domain containing 1
SYBU syntabulin (syntaxin-interacting)
SYT11 synaptotagmin XI
TRAFD1 TRAF-type zinc finger domain containing 1
TSC2 tuberous sclerosis 2
TUBA4A tubulin, alpha 4a
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
WDR19 WD repeat domain 19
ZCCHC14 zinc finger, CCHC domain containing 14
ZCCHC24 zinc finger, CCHC domain containing 24
ZDHHC11 zinc finger, DHHC-type containing 11

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ACVR2B activin A receptor, type IIB
ADNP activity-dependent neuroprotector homeobox
AKAP8 A kinase (PRKA) anchor protein 8
AMIGO2 adhesion molecule with Ig-like domain 2
AMOTL2 angiomotin like 2
ARHGAP11A Rho GTPase activating protein 11A
ATAD2B ATPase family, AAA domain containing 2B
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C7ORF49 chromosome 7 open reading frame 49
C9ORF91 chromosome 9 open reading frame 91
CALHM2 calcium homeostasis modulator 2
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCND1 cyclin D1
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CISH cytokine inducible SH2-containing protein
COA7 cytochrome c oxidase assembly factor 7 (putative)
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CUL1 cullin 1
DENND1B DENN/MADD domain containing 1B
DKK1 dickkopf WNT signaling pathway inhibitor 1
DSCAM Down syndrome cell adhesion molecule
EFNA1 ephrin-A1
EGR3 early growth response 3
FAM57A family with sequence similarity 57, member A
FJX1 four jointed box 1 (Drosophila)
FOXA1 forkhead box A1
FOXC1 forkhead box C1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GABPB1 GA binding protein transcription factor, beta subunit 1
GATA3 GATA binding protein 3
GOLPH3 golgi phosphoprotein 3 (coat-protein)
GTF2I general transcription factor IIi
H2AFY2 H2A histone family, member Y2
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HNRNPF heterogeneous nuclear ribonucleoprotein F
HOXC11 homeobox C11
IL4R interleukin 4 receptor
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
IRX5 iroquois homeobox 5
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITPKB inositol-trisphosphate 3-kinase B
JADE3 jade family PHD finger 3
KAT2A K(lysine) acetyltransferase 2A
KEAP1 kelch-like ECH-associated protein 1
KIAA0125 KIAA0125
LUC7L2 LUC7-like 2 (S. cerevisiae)
LY6G5C lymphocyte antigen 6 complex, locus G5C
MEPCE methylphosphate capping enzyme
MPPED2 metallophosphoesterase domain containing 2
MSL1 male-specific lethal 1 homolog (Drosophila)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NPY1R neuropeptide Y receptor Y1
NRIP1 nuclear receptor interacting protein 1
NSD1 nuclear receptor binding SET domain protein 1
NUAK1 NUAK family, SNF1-like kinase, 1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PHLDA3 pleckstrin homology-like domain, family A, member 3
POGK pogo transposable element with KRAB domain
POLR3B polymerase (RNA) III (DNA directed) polypeptide B
PRR15L proline rich 15-like
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM23 RNA binding motif protein 23
RDX radixin
RFX7 regulatory factor X, 7
RIPPLY3 ripply transcriptional repressor 3
SCAF8 SR-related CTD-associated factor 8
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SETD1B SET domain containing 1B
SMAD7 SMAD family member 7
SMYD5 SMYD family member 5
SNHG20 small nucleolar RNA host gene 20
SREK1 splicing regulatory glutamine/lysine-rich protein 1
STC2 stanniocalcin 2
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TGFB3 transforming growth factor, beta 3
TGIF1 TGFB-induced factor homeobox 1
TMEM30B transmembrane protein 30B
TRIB1 tribbles pseudokinase 1
TRIB3 tribbles pseudokinase 3
TRIM16 tripartite motif containing 16
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPS1 trichorhinophalangeal syndrome I
TSKU tsukushi, small leucine rich proteoglycan
XBP1 X-box binding protein 1
XPO1 exportin 1
ZBED1 zinc finger, BED-type containing 1
ZC3H4 zinc finger CCCH-type containing 4
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF573 zinc finger protein 573
ZNF692 zinc finger protein 692