trichostatin A-7453 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the trichostatin A-7453 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ACSF2 acyl-CoA synthetase family member 2
ADM adrenomedullin
AHNAK2 AHNAK nucleoprotein 2
AKAP12 A kinase (PRKA) anchor protein 12
ALDOC aldolase C, fructose-bisphosphate
ARL4C ADP-ribosylation factor-like 4C
ARMCX2 armadillo repeat containing, X-linked 2
BAIAP2 BAI1-associated protein 2
CCDC28A coiled-coil domain containing 28A
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CLGN calmegin
CORO1A coronin, actin binding protein, 1A
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSRP2 cysteine and glycine-rich protein 2
CXADR coxsackie virus and adenovirus receptor
CXCR4 chemokine (C-X-C motif) receptor 4
CYB5R1 cytochrome b5 reductase 1
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLX2 distal-less homeobox 2
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DPYSL4 dihydropyrimidinase-like 4
DUSP10 dual specificity phosphatase 10
EFNA3 ephrin-A3
EFNB3 ephrin-B3
EHBP1L1 EH domain binding protein 1-like 1
ELOVL4 ELOVL fatty acid elongase 4
EPOR erythropoietin receptor
FADS3 fatty acid desaturase 3
FKBP1B FK506 binding protein 1B, 12.6 kDa
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GCHFR GTP cyclohydrolase I feedback regulator
GEM GTP binding protein overexpressed in skeletal muscle
GLDC glycine dehydrogenase (decarboxylating)
GLRX glutaredoxin (thioltransferase)
GRK5 G protein-coupled receptor kinase 5
GSDMB gasdermin B
GTF2B general transcription factor IIB
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
IRF6 interferon regulatory factor 6
JAG1 jagged 1
KIAA0513 KIAA0513
KIF5C kinesin family member 5C
KLHL24 kelch-like family member 24
LIMA1 LIM domain and actin binding 1
LYST lysosomal trafficking regulator
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MARK4 MAP/microtubule affinity-regulating kinase 4
MVP major vault protein
NEK1 NIMA-related kinase 1
NME5 NME/NM23 family member 5
NME7 NME/NM23 family member 7
NPC1 Niemann-Pick disease, type C1
NUP62CL nucleoporin 62kDa C-terminal like
NXN nucleoredoxin
PAIP2B poly(A) binding protein interacting protein 2B
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDH9 protocadherin 9
PPARD peroxisome proliferator-activated receptor delta
PRPH peripherin
PTRF polymerase I and transcript release factor
RAB3A RAB3A, member RAS oncogene family
RAB40B RAB40B, member RAS oncogene family
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RTN2 reticulon 2
RUNDC3B RUN domain containing 3B
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPP1 selenoprotein P, plasma, 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SNAI2 snail family zinc finger 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STON1 stonin 1
STXBP1 syntaxin binding protein 1
SYT11 synaptotagmin XI
TRIM2 tripartite motif containing 2
TUFT1 tuftelin 1
WDR19 WD repeat domain 19
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZBTB18 zinc finger and BTB domain containing 18
ZBTB48 zinc finger and BTB domain containing 48
ZCCHC24 zinc finger, CCHC domain containing 24
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF10 zinc finger protein 10
ZNF204P zinc finger protein 204, pseudogene

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADNP activity-dependent neuroprotector homeobox
AEN apoptosis enhancing nuclease
AKAP8 A kinase (PRKA) anchor protein 8
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
BCAR3 breast cancer anti-estrogen resistance 3
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C7ORF49 chromosome 7 open reading frame 49
C9ORF91 chromosome 9 open reading frame 91
CALHM2 calcium homeostasis modulator 2
CAPN15 calpain 15
CASD1 CAS1 domain containing 1
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCND1 cyclin D1
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CXCL12 chemokine (C-X-C motif) ligand 12
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
EGR3 early growth response 3
ERN2 endoplasmic reticulum to nucleus signaling 2
FAIM Fas apoptotic inhibitory molecule
FJX1 four jointed box 1 (Drosophila)
FOXA1 forkhead box A1
FOXD1 forkhead box D1
GABPB1 GA binding protein transcription factor, beta subunit 1
GATA3 GATA binding protein 3
GMEB2 glucocorticoid modulatory element binding protein 2
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GRWD1 glutamate-rich WD repeat containing 1
GTF2I general transcription factor IIi
GTF2IRD1 GTF2I repeat domain containing 1
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
IRX5 iroquois homeobox 5
KAT5 K(lysine) acetyltransferase 5
KAT6B K(lysine) acetyltransferase 6B
KEAP1 kelch-like ECH-associated protein 1
LMNB1 lamin B1
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LUC7L2 LUC7-like 2 (S. cerevisiae)
MARC1 mitochondrial amidoxime reducing component 1
MCM9 minichromosome maintenance complex component 9
MEPCE methylphosphate capping enzyme
MPPED2 metallophosphoesterase domain containing 2
MSL1 male-specific lethal 1 homolog (Drosophila)
MYD88 myeloid differentiation primary response 88
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NME6 NME/NM23 nucleoside diphosphate kinase 6
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRIP1 nuclear receptor interacting protein 1
NSD1 nuclear receptor binding SET domain protein 1
NUAK1 NUAK family, SNF1-like kinase, 1
PCBP1 poly(rC) binding protein 1
PHF11 PHD finger protein 11
PHLDA3 pleckstrin homology-like domain, family A, member 3
PLK1 polo-like kinase 1
POGK pogo transposable element with KRAB domain
PRNP prion protein
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM4B RNA binding motif protein 4B
RIPPLY3 ripply transcriptional repressor 3
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SCAF8 SR-related CTD-associated factor 8
SETD1B SET domain containing 1B
SETD8 SET domain containing (lysine methyltransferase) 8
SIDT1 SID1 transmembrane family, member 1
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLTM SAFB-like, transcription modulator
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMG9 SMG9 nonsense mediated mRNA decay factor
SPHK1 sphingosine kinase 1
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SRSF4 serine/arginine-rich splicing factor 4
STC2 stanniocalcin 2
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
THEM6 thioesterase superfamily member 6
TMED1 transmembrane emp24 protein transport domain containing 1
TMEM30B transmembrane protein 30B
TOE1 target of EGR1, member 1 (nuclear)
TRIB3 tribbles pseudokinase 3
TRIM16 tripartite motif containing 16
TRIM8 tripartite motif containing 8
TRPS1 trichorhinophalangeal syndrome I
TSKU tsukushi, small leucine rich proteoglycan
TSSC4 tumor suppressing subtransferable candidate 4
UBTF upstream binding transcription factor, RNA polymerase I
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae)
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
XBP1 X-box binding protein 1
ZC3H4 zinc finger CCCH-type containing 4
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1
ZNF692 zinc finger protein 692