trichostatin A-7407 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the trichostatin A-7407 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ACSF2 acyl-CoA synthetase family member 2
ADD3 adducin 3 (gamma)
AHNAK2 AHNAK nucleoprotein 2
ARMCX2 armadillo repeat containing, X-linked 2
BCORL1 BCL6 corepressor-like 1
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CALCOCO1 calcium binding and coiled-coil domain 1
CCDC28A coiled-coil domain containing 28A
CORO1A coronin, actin binding protein, 1A
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYB5R1 cytochrome b5 reductase 1
CYLD cylindromatosis (turban tumor syndrome)
DHRS2 dehydrogenase/reductase (SDR family) member 2
DIXDC1 DIX domain containing 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DPYSL4 dihydropyrimidinase-like 4
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EGR1 early growth response 1
ELL2 elongation factor, RNA polymerase II, 2
EPOR erythropoietin receptor
FADS3 fatty acid desaturase 3
FAM214B family with sequence similarity 214, member B
FLRT3 fibronectin leucine rich transmembrane protein 3
FN1 fibronectin 1
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GCHFR GTP cyclohydrolase I feedback regulator
GEM GTP binding protein overexpressed in skeletal muscle
GLRX glutaredoxin (thioltransferase)
GRK5 G protein-coupled receptor kinase 5
GTF2B general transcription factor IIB
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HMOX1 heme oxygenase 1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IRF6 interferon regulatory factor 6
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KDM6A lysine (K)-specific demethylase 6A
KLHL24 kelch-like family member 24
LIMA1 LIM domain and actin binding 1
LMCD1 LIM and cysteine-rich domains 1
LYST lysosomal trafficking regulator
MAN1C1 mannosidase, alpha, class 1C, member 1
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MARK4 MAP/microtubule affinity-regulating kinase 4
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
NDRG1 N-myc downstream regulated 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NME5 NME/NM23 family member 5
NPC1 Niemann-Pick disease, type C1
NUP62CL nucleoporin 62kDa C-terminal like
NXN nucleoredoxin
PAIP2B poly(A) binding protein interacting protein 2B
PHF20L1 PHD finger protein 20-like 1
PRPH peripherin
PTRF polymerase I and transcript release factor
PVRL3 poliovirus receptor-related 3
RAB3A RAB3A, member RAS oncogene family
RAB40B RAB40B, member RAS oncogene family
RAI2 retinoic acid induced 2
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
RNFT2 ring finger protein, transmembrane 2
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RTN2 reticulon 2
RUNDC3B RUN domain containing 3B
SAT1 spermidine/spermine N1-acetyltransferase 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SFXN3 sideroflexin 3
SH3BGR SH3 domain binding glutamate-rich protein
SH3GL3 SH3-domain GRB2-like 3
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SSBP2 single-stranded DNA binding protein 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STARD5 StAR-related lipid transfer (START) domain containing 5
STON1 stonin 1
STXBP1 syntaxin binding protein 1
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TRIM2 tripartite motif containing 2
TRIM52 tripartite motif containing 52
TTBK2 tau tubulin kinase 2
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
UNC119 unc-119 homolog (C. elegans)
VCL vinculin
WDR19 WD repeat domain 19
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZCCHC24 zinc finger, CCHC domain containing 24
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF10 zinc finger protein 10
ZNF204P zinc finger protein 204, pseudogene

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADGRA3 adhesion G protein-coupled receptor A3
ADNP activity-dependent neuroprotector homeobox
ARMC7 armadillo repeat containing 7
ASTE1 asteroid homolog 1 (Drosophila)
BATF basic leucine zipper transcription factor, ATF-like
BRD9 bromodomain containing 9
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
CAPN15 calpain 15
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCND1 cyclin D1
CISH cytokine inducible SH2-containing protein
COA7 cytochrome c oxidase assembly factor 7 (putative)
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CTPS1 CTP synthase 1
CXCL12 chemokine (C-X-C motif) ligand 12
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
EGR3 early growth response 3
EXOSC10 exosome component 10
FADD Fas (TNFRSF6)-associated via death domain
FAM57A family with sequence similarity 57, member A
FJX1 four jointed box 1 (Drosophila)
FOXA1 forkhead box A1
FOXD1 forkhead box D1
GABPB1 GA binding protein transcription factor, beta subunit 1
GATA3 GATA binding protein 3
GTF2I general transcription factor IIi
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
IRX5 iroquois homeobox 5
KEAP1 kelch-like ECH-associated protein 1
KIF15 kinesin family member 15
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LMNB1 lamin B1
LPAR2 lysophosphatidic acid receptor 2
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
LUC7L2 LUC7-like 2 (S. cerevisiae)
MCM9 minichromosome maintenance complex component 9
MEPCE methylphosphate capping enzyme
MEX3C mex-3 RNA binding family member C
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MSL1 male-specific lethal 1 homolog (Drosophila)
MYC v-myc avian myelocytomatosis viral oncogene homolog
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NIP7 NIP7, nucleolar pre-rRNA processing protein
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NPY1R neuropeptide Y receptor Y1
NRIP1 nuclear receptor interacting protein 1
NSD1 nuclear receptor binding SET domain protein 1
NUAK1 NUAK family, SNF1-like kinase, 1
PFAS phosphoribosylformylglycinamidine synthase
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
POGK pogo transposable element with KRAB domain
PP14571 uncharacterized LOC100130449
PPAN peter pan homolog (Drosophila)
PRR7 proline rich 7 (synaptic)
PUS1 pseudouridylate synthase 1
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM23 RNA binding motif protein 23
RCL1 RNA terminal phosphate cyclase-like 1
REV1 REV1, polymerase (DNA directed)
RHOBTB1 Rho-related BTB domain containing 1
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SETD6 SET domain containing 6
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLTM SAFB-like, transcription modulator
SMAD7 SMAD family member 7
SMYD5 SMYD family member 5
SNHG20 small nucleolar RNA host gene 20
SPIN1 spindlin 1
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SRRD SRR1 domain containing
STC2 stanniocalcin 2
TMED1 transmembrane emp24 protein transport domain containing 1
TRIB3 tribbles pseudokinase 3
TRIM16 tripartite motif containing 16
TRIM8 tripartite motif containing 8
TRPS1 trichorhinophalangeal syndrome I
TSKU tsukushi, small leucine rich proteoglycan
UBTF upstream binding transcription factor, RNA polymerase I
UBXN8 UBX domain protein 8
URGCP upregulator of cell proliferation
USP6NL USP6 N-terminal like
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
VRK2 vaccinia related kinase 2
VWA9 von Willebrand factor A domain containing 9
WDR43 WD repeat domain 43
WDR74 WD repeat domain 74
XBP1 X-box binding protein 1
YAP1 Yes-associated protein 1
ZC3H4 zinc finger CCCH-type containing 4
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1