trichostatin A-7387 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the trichostatin A-7387 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGTR1 angiotensin II receptor, type 1
AQP3 aquaporin 3 (Gill blood group)
ARG2 arginase 2
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASMTL acetylserotonin O-methyltransferase-like
BAIAP2 BAI1-associated protein 2
BAMBI BMP and activin membrane-bound inhibitor
BCL6 B-cell CLL/lymphoma 6
BMP6 bone morphogenetic protein 6
CCL20 chemokine (C-C motif) ligand 20
CCNA1 cyclin A1
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CFAP69 cilia and flagella associated protein 69
CORO1A coronin, actin binding protein, 1A
CPM carboxypeptidase M
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTGF connective tissue growth factor
CTH cystathionine gamma-lyase
CXCR4 chemokine (C-X-C motif) receptor 4
DFNB31 deafness, autosomal recessive 31
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DUSP1 dual specificity phosphatase 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFNA3 ephrin-A3
EGR2 early growth response 2
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ENOX1 ecto-NOX disulfide-thiol exchanger 1
EPHB3 EPH receptor B3
FABP4 fatty acid binding protein 4, adipocyte
FAM69A family with sequence similarity 69, member A
FYN FYN proto-oncogene, Src family tyrosine kinase
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GLCE glucuronic acid epimerase
GLS glutaminase
GPRC5A G protein-coupled receptor, class C, group 5, member A
GUCY1B3 guanylate cyclase 1, soluble, beta 3
H1FX H1 histone family, member X
HOXA1 homeobox A1
IL11 interleukin 11
IL1RAP interleukin 1 receptor accessory protein
IRF6 interferon regulatory factor 6
IRS2 insulin receptor substrate 2
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIF5C kinesin family member 5C
KITLG KIT ligand
LINC00341 long intergenic non-protein coding RNA 341
LMCD1 LIM and cysteine-rich domains 1
LPIN1 lipin 1
LPPR4 lipid phosphate phosphatase-related protein type 4
LYST lysosomal trafficking regulator
MARK4 MAP/microtubule affinity-regulating kinase 4
MERTK MER proto-oncogene, tyrosine kinase
MLF1 myeloid leukemia factor 1
MMP1 matrix metallopeptidase 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NR4A2 nuclear receptor subfamily 4, group A, member 2
OASL 2'-5'-oligoadenylate synthetase-like
PCDH9 protocadherin 9
PDE4DIP phosphodiesterase 4D interacting protein
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PER1 period circadian clock 1
PLSCR4 phospholipid scramblase 4
PLXNA3 plexin A3
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKCD protein kinase C, delta
PRPH peripherin
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS4 regulator of G-protein signaling 4
RHOB ras homolog family member B
RNF24 ring finger protein 24
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SHROOM2 shroom family member 2
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC31A2 solute carrier family 31 (copper transporter), member 2
SPTAN1 spectrin, alpha, non-erythrocytic 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STC1 stanniocalcin 1
STOM stomatin
SYT1 synaptotagmin I
SYT11 synaptotagmin XI
SYTL2 synaptotagmin-like 2
TAGLN3 transgelin 3
TAOK3 TAO kinase 3
TESK2 testis-specific kinase 2
TMSB15A thymosin beta 15a
TNIK TRAF2 and NCK interacting kinase
TPST2 tyrosylprotein sulfotransferase 2
TRAFD1 TRAF-type zinc finger domain containing 1
TUBB2B tubulin, beta 2B class IIb
TUFT1 tuftelin 1
USP2 ubiquitin specific peptidase 2

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADNP activity-dependent neuroprotector homeobox
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARSJ arylsulfatase family, member J
ATF1 activating transcription factor 1
BANP BTG3 associated nuclear protein
BCAR3 breast cancer anti-estrogen resistance 3
BCL7A B-cell CLL/lymphoma 7A
BNC2 basonuclin 2
CASD1 CAS1 domain containing 1
CBR3 carbonyl reductase 3
CCDC94 coiled-coil domain containing 94
CDC7 cell division cycle 7
CLCF1 cardiotrophin-like cytokine factor 1
COA7 cytochrome c oxidase assembly factor 7 (putative)
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CUL1 cullin 1
DENND4B DENN/MADD domain containing 4B
DEPDC1 DEP domain containing 1
ERN2 endoplasmic reticulum to nucleus signaling 2
EXOSC10 exosome component 10
FADD Fas (TNFRSF6)-associated via death domain
FAIM Fas apoptotic inhibitory molecule
FJX1 four jointed box 1 (Drosophila)
FOSL1 FOS-like antigen 1
FOXA1 forkhead box A1
FST follistatin
FZD8 frizzled class receptor 8
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GABPB1 GA binding protein transcription factor, beta subunit 1
GBX2 gastrulation brain homeobox 2
GMEB2 glucocorticoid modulatory element binding protein 2
GTF2IRD1 GTF2I repeat domain containing 1
H2AFY2 H2A histone family, member Y2
HAS2 hyaluronan synthase 2
HMGA2 high mobility group AT-hook 2
IL7R interleukin 7 receptor
INHBB inhibin, beta B
KAT5 K(lysine) acetyltransferase 5
KAT6B K(lysine) acetyltransferase 6B
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KEAP1 kelch-like ECH-associated protein 1
KLF11 Kruppel-like factor 11
LIF leukemia inhibitory factor
LMNB1 lamin B1
LPAR1 lysophosphatidic acid receptor 1
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
MEPCE methylphosphate capping enzyme
METTL1 methyltransferase like 1
METTL4 methyltransferase like 4
MID1IP1 MID1 interacting protein 1
MSL1 male-specific lethal 1 homolog (Drosophila)
MTPAP mitochondrial poly(A) polymerase
NHEJ1 nonhomologous end-joining factor 1
NME6 NME/NM23 nucleoside diphosphate kinase 6
NRIP1 nuclear receptor interacting protein 1
NUP62 nucleoporin 62kDa
PARP12 poly (ADP-ribose) polymerase family, member 12
PLAU plasminogen activator, urokinase
PLK1 polo-like kinase 1
PPAN peter pan homolog (Drosophila)
QRICH1 glutamine-rich 1
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RBL1 retinoblastoma-like 1
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RIN2 Ras and Rab interactor 2
RNF123 ring finger protein 123
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SFMBT1 Scm-like with four mbt domains 1
SH2D4A SH2 domain containing 4A
SIM2 single-minded family bHLH transcription factor 2
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SMAGP small cell adhesion glycoprotein
SMG9 SMG9 nonsense mediated mRNA decay factor
SMYD5 SMYD family member 5
SPHK1 sphingosine kinase 1
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SRSF4 serine/arginine-rich splicing factor 4
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STBD1 starch binding domain 1
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SYNPO synaptopodin
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TRIB3 tribbles pseudokinase 3
TSSC4 tumor suppressing subtransferable candidate 4
UNKL unkempt family zinc finger-like
VEGFC vascular endothelial growth factor C
VWA9 von Willebrand factor A domain containing 9
ZBED1 zinc finger, BED-type containing 1
ZBTB38 zinc finger and BTB domain containing 38
ZC3H4 zinc finger CCCH-type containing 4
ZNF16 zinc finger protein 16
ZNF33B zinc finger protein 33B
ZNF692 zinc finger protein 692
ZNF804A zinc finger protein 804A
ZNF85 zinc finger protein 85
ZZZ3 zinc finger, ZZ-type containing 3