trichostatin A-7245 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the trichostatin A-7245 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD6 abhydrolase domain containing 6
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ADM adrenomedullin
AGTR1 angiotensin II receptor, type 1
AQP3 aquaporin 3 (Gill blood group)
AREG amphiregulin
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASMTL acetylserotonin O-methyltransferase-like
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
AVPI1 arginine vasopressin-induced 1
BAIAP2 BAI1-associated protein 2
BAMBI BMP and activin membrane-bound inhibitor
C18ORF8 chromosome 18 open reading frame 8
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFAP69 cilia and flagella associated protein 69
CORO1A coronin, actin binding protein, 1A
CPM carboxypeptidase M
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTGF connective tissue growth factor
CTH cystathionine gamma-lyase
CXCR4 chemokine (C-X-C motif) receptor 4
CYB5R1 cytochrome b5 reductase 1
CYR61 cysteine-rich, angiogenic inducer, 61
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
DUSP5 dual specificity phosphatase 5
EFNA3 ephrin-A3
EFNB2 ephrin-B2
ELOVL4 ELOVL fatty acid elongase 4
EPB41L5 erythrocyte membrane protein band 4.1 like 5
FABP4 fatty acid binding protein 4, adipocyte
FAM69A family with sequence similarity 69, member A
FGFR1 fibroblast growth factor receptor 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GLS glutaminase
GMPR guanosine monophosphate reductase
GPRC5A G protein-coupled receptor, class C, group 5, member A
GTF2B general transcription factor IIB
GUCY1B3 guanylate cyclase 1, soluble, beta 3
H1F0 H1 histone family, member 0
H1FX H1 histone family, member X
HBEGF heparin-binding EGF-like growth factor
HOXA1 homeobox A1
IGSF3 immunoglobulin superfamily, member 3
IL11 interleukin 11
INSIG1 insulin induced gene 1
IRF6 interferon regulatory factor 6
IRS2 insulin receptor substrate 2
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIF5C kinesin family member 5C
KLF2 Kruppel-like factor 2
LMCD1 LIM and cysteine-rich domains 1
MAP2K3 mitogen-activated protein kinase kinase 3
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MLF1 myeloid leukemia factor 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NFIL3 nuclear factor, interleukin 3 regulated
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRXN3 neurexin 3
PCDH9 protocadherin 9
PDE4DIP phosphodiesterase 4D interacting protein
PELI2 pellino E3 ubiquitin protein ligase family member 2
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PKP2 plakophilin 2
PLK2 polo-like kinase 2
PTCH1 patched 1
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAI2 retinoic acid induced 2
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS4 regulator of G-protein signaling 4
RNF24 ring finger protein 24
SCML1 sex comb on midleg-like 1 (Drosophila)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SHROOM2 shroom family member 2
SLC25A44 solute carrier family 25, member 44
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STC1 stanniocalcin 1
STK17B serine/threonine kinase 17b
STOM stomatin
SYT1 synaptotagmin I
TAOK3 TAO kinase 3
TBPL1 TBP-like 1
TESK2 testis-specific kinase 2
TMEM47 transmembrane protein 47
TRAFD1 TRAF-type zinc finger domain containing 1
TUBB2B tubulin, beta 2B class IIb
TUFT1 tuftelin 1
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
ADNP activity-dependent neuroprotector homeobox
ARSJ arylsulfatase family, member J
BCAR3 breast cancer anti-estrogen resistance 3
BHLHE41 basic helix-loop-helix family, member e41
BNC2 basonuclin 2
CASD1 CAS1 domain containing 1
CBR3 carbonyl reductase 3
CLASP1 cytoplasmic linker associated protein 1
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CUL1 cullin 1
DEPDC1 DEP domain containing 1
DET1 de-etiolated homolog 1 (Arabidopsis)
DOLK dolichol kinase
DSN1 DSN1, MIS12 kinetochore complex component
EXOSC10 exosome component 10
FJX1 four jointed box 1 (Drosophila)
FOXA1 forkhead box A1
FST follistatin
GBX2 gastrulation brain homeobox 2
GTF2IRD1 GTF2I repeat domain containing 1
HAS2 hyaluronan synthase 2
HMGA2 high mobility group AT-hook 2
INHBB inhibin, beta B
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
INPPL1 inositol polyphosphate phosphatase-like 1
ITPKB inositol-trisphosphate 3-kinase B
KAT6B K(lysine) acetyltransferase 6B
KEAP1 kelch-like ECH-associated protein 1
KIF15 kinesin family member 15
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LIF leukemia inhibitory factor
LMNB1 lamin B1
LPAR1 lysophosphatidic acid receptor 1
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
MEPCE methylphosphate capping enzyme
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MSL1 male-specific lethal 1 homolog (Drosophila)
MTIF2 mitochondrial translational initiation factor 2
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NME6 NME/NM23 nucleoside diphosphate kinase 6
NMI N-myc (and STAT) interactor
NR1H2 nuclear receptor subfamily 1, group H, member 2
NSD1 nuclear receptor binding SET domain protein 1
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
NUAK1 NUAK family, SNF1-like kinase, 1
NUP62 nucleoporin 62kDa
PAGR1 PAXIP1 associated glutamate-rich protein 1
PARP4 poly (ADP-ribose) polymerase family, member 4
PCNT pericentrin
PHF11 PHD finger protein 11
PMM2 phosphomannomutase 2
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD)
PPAP2B phosphatidic acid phosphatase type 2B
PRCC papillary renal cell carcinoma (translocation-associated)
QRICH1 glutamine-rich 1
RBM23 RNA binding motif protein 23
RBM39 RNA binding motif protein 39
RBM4B RNA binding motif protein 4B
RIN2 Ras and Rab interactor 2
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SCAF8 SR-related CTD-associated factor 8
SCO2 SCO2 cytochrome c oxidase assembly protein
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SETMAR SET domain and mariner transposase fusion gene
SIM2 single-minded family bHLH transcription factor 2
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SMA4 glucuronidase, beta pseudogene
SMAGP small cell adhesion glycoprotein
SNUPN snurportin 1
SPHK1 sphingosine kinase 1
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SRSF4 serine/arginine-rich splicing factor 4
STRN4 striatin, calmodulin binding protein 4
STXBP3 syntaxin binding protein 3
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa
TCEAL1 transcription elongation factor A (SII)-like 1
TCERG1 transcription elongation regulator 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TMPO thymopoietin
TOE1 target of EGR1, member 1 (nuclear)
TRIB3 tribbles pseudokinase 3
TSSC4 tumor suppressing subtransferable candidate 4
TUBGCP5 tubulin, gamma complex associated protein 5
UBL4A ubiquitin-like 4A
UBXN8 UBX domain protein 8
VEGFC vascular endothelial growth factor C
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
WBSCR16 Williams-Beuren syndrome chromosome region 16
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial
ZC3H4 zinc finger CCCH-type containing 4
ZNF282 zinc finger protein 282
ZNF32 zinc finger protein 32
ZNF532 zinc finger protein 532
ZNF562 zinc finger protein 562
ZNF692 zinc finger protein 692
ZZZ3 zinc finger, ZZ-type containing 3