trichostatin A-7236 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the trichostatin A-7236 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ACSF2 acyl-CoA synthetase family member 2
ADD3 adducin 3 (gamma)
ADM adrenomedullin
AHNAK2 AHNAK nucleoprotein 2
AKAP12 A kinase (PRKA) anchor protein 12
AKR1C3 aldo-keto reductase family 1, member C3
ALDOC aldolase C, fructose-bisphosphate
ANXA1 annexin A1
ARL4D ADP-ribosylation factor-like 4D
ARMCX2 armadillo repeat containing, X-linked 2
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
BAIAP3 BAI1-associated protein 3
C8ORF60 chromosome 8 open reading frame 60
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CLGN calmegin
CLMN calmin (calponin-like, transmembrane)
CORO1A coronin, actin binding protein, 1A
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CXADR coxsackie virus and adenovirus receptor
CXCR4 chemokine (C-X-C motif) receptor 4
CYB5R1 cytochrome b5 reductase 1
CYLD cylindromatosis (turban tumor syndrome)
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLX2 distal-less homeobox 2
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DPYSL4 dihydropyrimidinase-like 4
EAF2 ELL associated factor 2
EFNA3 ephrin-A3
EFNB3 ephrin-B3
ELOVL4 ELOVL fatty acid elongase 4
EPOR erythropoietin receptor
FOLR1 folate receptor 1 (adult)
FYN FYN proto-oncogene, Src family tyrosine kinase
GCHFR GTP cyclohydrolase I feedback regulator
GEM GTP binding protein overexpressed in skeletal muscle
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GLCE glucuronic acid epimerase
GLDC glycine dehydrogenase (decarboxylating)
GLRX glutaredoxin (thioltransferase)
GLS glutaminase
GRK5 G protein-coupled receptor kinase 5
GTF2B general transcription factor IIB
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
ITM2C integral membrane protein 2C
KATNB1 katanin p80 (WD repeat containing) subunit B 1
LIMA1 LIM domain and actin binding 1
LPCAT3 lysophosphatidylcholine acyltransferase 3
LPIN1 lipin 1
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MLF1 myeloid leukemia factor 1
MXI1 MAX interactor 1, dimerization protein
NES nestin
NME5 NME/NM23 family member 5
NPC1 Niemann-Pick disease, type C1
NXN nucleoredoxin
PADI3 peptidyl arginine deiminase, type III
PAIP2B poly(A) binding protein interacting protein 2B
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDE4DIP phosphodiesterase 4D interacting protein
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PMEL premelanosome protein
PRPH peripherin
PTRF polymerase I and transcript release factor
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
RND1 Rho family GTPase 1
RTN2 reticulon 2
RUNDC3B RUN domain containing 3B
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPP1 selenoprotein P, plasma, 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SIRT4 sirtuin 4
SLC30A3 solute carrier family 30 (zinc transporter), member 3
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STK17A serine/threonine kinase 17a
STON1 stonin 1
STXBP1 syntaxin binding protein 1
TESC tescalcin
TRIM2 tripartite motif containing 2
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
ULBP2 UL16 binding protein 2
UNC119 unc-119 homolog (C. elegans)
WDR19 WD repeat domain 19
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZCCHC14 zinc finger, CCHC domain containing 14
ZCCHC24 zinc finger, CCHC domain containing 24
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF10 zinc finger protein 10
ZNF204P zinc finger protein 204, pseudogene

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADGRA3 adhesion G protein-coupled receptor A3
ADNP activity-dependent neuroprotector homeobox
AKAP10 A kinase (PRKA) anchor protein 10
AKAP8 A kinase (PRKA) anchor protein 8
AMIGO2 adhesion molecule with Ig-like domain 2
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C9ORF40 chromosome 9 open reading frame 40
CALHM2 calcium homeostasis modulator 2
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCDC94 coiled-coil domain containing 94
CCND1 cyclin D1
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
DKK1 dickkopf WNT signaling pathway inhibitor 1
EGR3 early growth response 3
ESRP2 epithelial splicing regulatory protein 2
FHOD1 formin homology 2 domain containing 1
FJX1 four jointed box 1 (Drosophila)
FOXA1 forkhead box A1
FOXC1 forkhead box C1
FOXD1 forkhead box D1
GABPB1 GA binding protein transcription factor, beta subunit 1
GATA3 GATA binding protein 3
GPR87 G protein-coupled receptor 87
GRWD1 glutamate-rich WD repeat containing 1
GTF2IRD1 GTF2I repeat domain containing 1
HIRIP3 HIRA interacting protein 3
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HOXC11 homeobox C11
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
IRX4 iroquois homeobox 4
IRX5 iroquois homeobox 5
KAT2A K(lysine) acetyltransferase 2A
KEAP1 kelch-like ECH-associated protein 1
LMNB1 lamin B1
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LUC7L2 LUC7-like 2 (S. cerevisiae)
LY6G5C lymphocyte antigen 6 complex, locus G5C
MARC1 mitochondrial amidoxime reducing component 1
MEPCE methylphosphate capping enzyme
MSL1 male-specific lethal 1 homolog (Drosophila)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRIP1 nuclear receptor interacting protein 1
NSD1 nuclear receptor binding SET domain protein 1
NUAK1 NUAK family, SNF1-like kinase, 1
OSMR oncostatin M receptor
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PLEKHO1 pleckstrin homology domain containing, family O member 1
POGK pogo transposable element with KRAB domain
POLR3B polymerase (RNA) III (DNA directed) polypeptide B
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD)
PPAN peter pan homolog (Drosophila)
PRR15L proline rich 15-like
PTBP2 polypyrimidine tract binding protein 2
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM23 RNA binding motif protein 23
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SARS2 seryl-tRNA synthetase 2, mitochondrial
SETD1B SET domain containing 1B
SFMBT1 Scm-like with four mbt domains 1
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMAD7 SMAD family member 7
SMG9 SMG9 nonsense mediated mRNA decay factor
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SRSF4 serine/arginine-rich splicing factor 4
STC2 stanniocalcin 2
TGFB3 transforming growth factor, beta 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM223 transmembrane protein 223
TPTE transmembrane phosphatase with tensin homology
TRAF5 TNF receptor-associated factor 5
TRIB3 tribbles pseudokinase 3
TRIM16 tripartite motif containing 16
TRIM8 tripartite motif containing 8
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSKU tsukushi, small leucine rich proteoglycan
UBTF upstream binding transcription factor, RNA polymerase I
UNKL unkempt family zinc finger-like
WDR43 WD repeat domain 43
XBP1 X-box binding protein 1
YAP1 Yes-associated protein 1
ZC3H4 zinc finger CCCH-type containing 4
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1
ZNF586 zinc finger protein 586
ZNF652 zinc finger protein 652
ZNF692 zinc finger protein 692
ZNF787 zinc finger protein 787
ZNHIT2 zinc finger, HIT-type containing 2