trichostatin A-7077 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the trichostatin A-7077 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABHD17B abhydrolase domain containing 17B
ABHD6 abhydrolase domain containing 6
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ADM adrenomedullin
ADRB2 adrenoceptor beta 2, surface
AGFG2 ArfGAP with FG repeats 2
AIM1L absent in melanoma 1-like
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
ANGPTL4 angiopoietin-like 4
AQP3 aquaporin 3 (Gill blood group)
ARG2 arginase 2
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASMTL acetylserotonin O-methyltransferase-like
AVPI1 arginine vasopressin-induced 1
BAIAP2 BAI1-associated protein 2
BAMBI BMP and activin membrane-bound inhibitor
BEX1 brain expressed, X-linked 1
BIRC3 baculoviral IAP repeat containing 3
BMP6 bone morphogenetic protein 6
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEP112 centrosomal protein 112kDa
CFAP69 cilia and flagella associated protein 69
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CORO1A coronin, actin binding protein, 1A
CPA4 carboxypeptidase A4
CPD carboxypeptidase D
CPM carboxypeptidase M
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTGF connective tissue growth factor
CTH cystathionine gamma-lyase
CYR61 cysteine-rich, angiogenic inducer, 61
DDIT4 DNA-damage-inducible transcript 4
DENND3 DENN/MADD domain containing 3
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
DUSP5 dual specificity phosphatase 5
EFNB2 ephrin-B2
EGR2 early growth response 2
EPHA4 EPH receptor A4
EPPK1 epiplakin 1
FABP4 fatty acid binding protein 4, adipocyte
FAM134B family with sequence similarity 134, member B
FLRT3 fibronectin leucine rich transmembrane protein 3
GCDH glutaryl-CoA dehydrogenase
GEM GTP binding protein overexpressed in skeletal muscle
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GLS glutaminase
GMCL1 germ cell-less, spermatogenesis associated 1
GPRC5A G protein-coupled receptor, class C, group 5, member A
GTF2B general transcription factor IIB
HBEGF heparin-binding EGF-like growth factor
HMOX1 heme oxygenase 1
HOXA1 homeobox A1
IL11 interleukin 11
IL1RAP interleukin 1 receptor accessory protein
INSIG1 insulin induced gene 1
IRF6 interferon regulatory factor 6
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIAA0930 KIAA0930
LIFR leukemia inhibitory factor receptor alpha
LMCD1 LIM and cysteine-rich domains 1
LPIN1 lipin 1
MERTK MER proto-oncogene, tyrosine kinase
MMP1 matrix metallopeptidase 1
MSX2 msh homeobox 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NEU1 sialidase 1 (lysosomal sialidase)
NR4A1 nuclear receptor subfamily 4, group A, member 1
OASL 2'-5'-oligoadenylate synthetase-like
PELI1 pellino E3 ubiquitin protein ligase 1
PER1 period circadian clock 1
PEX1 peroxisomal biogenesis factor 1
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAI2 retinoic acid induced 2
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS4 regulator of G-protein signaling 4
RHOB ras homolog family member B
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC31A2 solute carrier family 31 (copper transporter), member 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STC1 stanniocalcin 1
SYT1 synaptotagmin I
SYTL2 synaptotagmin-like 2
TJP3 tight junction protein 3
TMEM47 transmembrane protein 47
TRAFD1 TRAF-type zinc finger domain containing 1
TRIM62 tripartite motif containing 62
TUBB2B tubulin, beta 2B class IIb
TUFT1 tuftelin 1
ZFP36 ZFP36 ring finger protein
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
ADNP activity-dependent neuroprotector homeobox
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
BCAR3 breast cancer anti-estrogen resistance 3
BCL7A B-cell CLL/lymphoma 7A
BMI1 BMI1 proto-oncogene, polycomb ring finger
C3ORF18 chromosome 3 open reading frame 18
CASD1 CAS1 domain containing 1
CBR3 carbonyl reductase 3
CENPA centromere protein A
CLCF1 cardiotrophin-like cytokine factor 1
CTCF CCCTC-binding factor (zinc finger protein)
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CUL1 cullin 1
DCTN4 dynactin 4 (p62)
DENND1B DENN/MADD domain containing 1B
DEPDC1 DEP domain containing 1
DSN1 DSN1, MIS12 kinetochore complex component
DUSP4 dual specificity phosphatase 4
E2F8 E2F transcription factor 8
FADD Fas (TNFRSF6)-associated via death domain
FAIM Fas apoptotic inhibitory molecule
FAM169A family with sequence similarity 169, member A
FAM57A family with sequence similarity 57, member A
FJX1 four jointed box 1 (Drosophila)
FOSL1 FOS-like antigen 1
FOXA1 forkhead box A1
FST follistatin
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
H2AFY2 H2A histone family, member Y2
HAS2 hyaluronan synthase 2
HMGA2 high mobility group AT-hook 2
HMGXB4 HMG box domain containing 4
HOOK1 hook microtubule-tethering protein 1
HSPB8 heat shock 22kDa protein 8
IL33 interleukin 33
IL4R interleukin 4 receptor
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
KAT6B K(lysine) acetyltransferase 6B
KEAP1 kelch-like ECH-associated protein 1
LMNB1 lamin B1
LPAR1 lysophosphatidic acid receptor 1
LRIF1 ligand dependent nuclear receptor interacting factor 1
LUC7L2 LUC7-like 2 (S. cerevisiae)
MANSC1 MANSC domain containing 1
MCM9 minichromosome maintenance complex component 9
MEPCE methylphosphate capping enzyme
METTL4 methyltransferase like 4
MEX3C mex-3 RNA binding family member C
NDC80 NDC80 kinetochore complex component
NHEJ1 nonhomologous end-joining factor 1
NRIP1 nuclear receptor interacting protein 1
NSD1 nuclear receptor binding SET domain protein 1
NUP62 nucleoporin 62kDa
NUPR1 nuclear protein, transcriptional regulator, 1
PALMD palmdelphin
PCNT pericentrin
PPAN peter pan homolog (Drosophila)
PPAP2B phosphatidic acid phosphatase type 2B
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RBM23 RNA binding motif protein 23
RIN2 Ras and Rab interactor 2
RIPPLY3 ripply transcriptional repressor 3
SCAF8 SR-related CTD-associated factor 8
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SETD1B SET domain containing 1B
SETMAR SET domain and mariner transposase fusion gene
SH2D4A SH2 domain containing 4A
SIDT1 SID1 transmembrane family, member 1
SIM2 single-minded family bHLH transcription factor 2
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
SMAGP small cell adhesion glycoprotein
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SNX5 sorting nexin 5
SPRY2 sprouty homolog 2 (Drosophila)
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SRSF4 serine/arginine-rich splicing factor 4
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TARBP2 TAR (HIV-1) RNA binding protein 2
TCERG1 transcription elongation regulator 1
TEX264 testis expressed 264
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TOE1 target of EGR1, member 1 (nuclear)
TRIB3 tribbles pseudokinase 3
TRIM8 tripartite motif containing 8
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae)
TSSC4 tumor suppressing subtransferable candidate 4
TWF2 twinfilin actin binding protein 2
VEGFC vascular endothelial growth factor C
XBP1 X-box binding protein 1
ZBED8 zinc finger, BED-type containing 8
ZBTB44 zinc finger and BTB domain containing 44
ZC3H4 zinc finger CCCH-type containing 4
ZNF165 zinc finger protein 165
ZNF248 zinc finger protein 248
ZNF32 zinc finger protein 32
ZNF692 zinc finger protein 692
ZZZ3 zinc finger, ZZ-type containing 3