trichostatin A-7073 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the trichostatin A-7073 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ADRB2 adrenoceptor beta 2, surface
ANGPTL4 angiopoietin-like 4
ANOS1 anosmin 1
AQP3 aquaporin 3 (Gill blood group)
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASMTL acetylserotonin O-methyltransferase-like
AVPI1 arginine vasopressin-induced 1
BAIAP2 BAI1-associated protein 2
BAMBI BMP and activin membrane-bound inhibitor
BMP6 bone morphogenetic protein 6
C16ORF45 chromosome 16 open reading frame 45
C6ORF106 chromosome 6 open reading frame 106
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFAP69 cilia and flagella associated protein 69
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLU clusterin
CORO1A coronin, actin binding protein, 1A
CPA4 carboxypeptidase A4
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTGF connective tissue growth factor
CYB5R1 cytochrome b5 reductase 1
CYR61 cysteine-rich, angiogenic inducer, 61
DBP D site of albumin promoter (albumin D-box) binding protein
DENND3 DENN/MADD domain containing 3
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DPF3 D4, zinc and double PHD fingers, family 3
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFNB2 ephrin-B2
EPPK1 epiplakin 1
FABP4 fatty acid binding protein 4, adipocyte
FAM134B family with sequence similarity 134, member B
FYN FYN proto-oncogene, Src family tyrosine kinase
GAREM GRB2 associated, regulator of MAPK1
GCDH glutaryl-CoA dehydrogenase
GEM GTP binding protein overexpressed in skeletal muscle
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GLRX glutaredoxin (thioltransferase)
GMPR guanosine monophosphate reductase
GPRC5A G protein-coupled receptor, class C, group 5, member A
GUCY1B3 guanylate cyclase 1, soluble, beta 3
H1FX H1 histone family, member X
HIST3H2A histone cluster 3, H2a
HOXA1 homeobox A1
HSPA2 heat shock 70kDa protein 2
IL11 interleukin 11
INSIG1 insulin induced gene 1
IRF6 interferon regulatory factor 6
IRS2 insulin receptor substrate 2
JUNB jun B proto-oncogene
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIF5C kinesin family member 5C
KLF2 Kruppel-like factor 2
LMCD1 LIM and cysteine-rich domains 1
LPPR4 lipid phosphate phosphatase-related protein type 4
MAP2K3 mitogen-activated protein kinase kinase 3
MAPT microtubule-associated protein tau
MERTK MER proto-oncogene, tyrosine kinase
MLF1 myeloid leukemia factor 1
MMP1 matrix metallopeptidase 1
MMP16 matrix metallopeptidase 16 (membrane-inserted)
NEU1 sialidase 1 (lysosomal sialidase)
NFIL3 nuclear factor, interleukin 3 regulated
NR4A1 nuclear receptor subfamily 4, group A, member 1
NXN nucleoredoxin
OASL 2'-5'-oligoadenylate synthetase-like
PAIP2B poly(A) binding protein interacting protein 2B
PARD6A par-6 family cell polarity regulator alpha
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PPL periplakin
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAI2 retinoic acid induced 2
RBBP6 retinoblastoma binding protein 6
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS4 regulator of G-protein signaling 4
RHOB ras homolog family member B
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SPTAN1 spectrin, alpha, non-erythrocytic 1
SREBF1 sterol regulatory element binding transcription factor 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STC1 stanniocalcin 1
STOM stomatin
SYT1 synaptotagmin I
TAGLN3 transgelin 3
TAOK3 TAO kinase 3
TJP3 tight junction protein 3
TRAFD1 TRAF-type zinc finger domain containing 1
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb
TUFT1 tuftelin 1

decreased expression

Symbol Name
ADGRG6 adhesion G protein-coupled receptor G6
ADNP activity-dependent neuroprotector homeobox
AEN apoptosis enhancing nuclease
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APH1A APH1A gamma secretase subunit
ARSJ arylsulfatase family, member J
BAG2 BCL2-associated athanogene 2
BAX BCL2-associated X protein
BCAR3 breast cancer anti-estrogen resistance 3
C11ORF30 chromosome 11 open reading frame 30
C17ORF75 chromosome 17 open reading frame 75
CBR3 carbonyl reductase 3
CDC7 cell division cycle 7
CENPA centromere protein A
COA7 cytochrome c oxidase assembly factor 7 (putative)
CTCF CCCTC-binding factor (zinc finger protein)
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CUL1 cullin 1
DEPDC1 DEP domain containing 1
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DUSP4 dual specificity phosphatase 4
EVPL envoplakin
EXOSC10 exosome component 10
EYA4 EYA transcriptional coactivator and phosphatase 4
FAIM Fas apoptotic inhibitory molecule
FAM169A family with sequence similarity 169, member A
FJX1 four jointed box 1 (Drosophila)
FOSL1 FOS-like antigen 1
FOXA1 forkhead box A1
FST follistatin
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GBX2 gastrulation brain homeobox 2
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HAS2 hyaluronan synthase 2
HIPK2 homeodomain interacting protein kinase 2
HIRA histone cell cycle regulator
HMGA2 high mobility group AT-hook 2
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
KEAP1 kelch-like ECH-associated protein 1
KIF20A kinesin family member 20A
KIFC1 kinesin family member C1
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LIF leukemia inhibitory factor
LMNB1 lamin B1
LPAR1 lysophosphatidic acid receptor 1
LRIF1 ligand dependent nuclear receptor interacting factor 1
LRRC37A3 leucine rich repeat containing 37, member A3
MAGOH mago-nashi homolog, proliferation-associated (Drosophila)
MED24 mediator complex subunit 24
MOCOS molybdenum cofactor sulfurase
MSL1 male-specific lethal 1 homolog (Drosophila)
MSL2 male-specific lethal 2 homolog (Drosophila)
NDC80 NDC80 kinetochore complex component
NLRX1 NLR family member X1
NME6 NME/NM23 nucleoside diphosphate kinase 6
NMI N-myc (and STAT) interactor
NR2F1 nuclear receptor subfamily 2, group F, member 1
NRIP1 nuclear receptor interacting protein 1
NSD1 nuclear receptor binding SET domain protein 1
PALMD palmdelphin
PCNT pericentrin
PEX26 peroxisomal biogenesis factor 26
PPAN peter pan homolog (Drosophila)
PPAP2B phosphatidic acid phosphatase type 2B
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PYCARD PYD and CARD domain containing
QTRT1 queuine tRNA-ribosyltransferase 1
RBM39 RNA binding motif protein 39
RIN2 Ras and Rab interactor 2
SCO2 SCO2 cytochrome c oxidase assembly protein
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SETD1B SET domain containing 1B
SF3A3 splicing factor 3a, subunit 3, 60kDa
SFMBT1 Scm-like with four mbt domains 1
SIM2 single-minded family bHLH transcription factor 2
SMAGP small cell adhesion glycoprotein
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SRSF4 serine/arginine-rich splicing factor 4
ST5 suppression of tumorigenicity 5
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TRIB3 tribbles pseudokinase 3
TRIM16 tripartite motif containing 16
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae)
UBTF upstream binding transcription factor, RNA polymerase I
VEGFC vascular endothelial growth factor C
ZC3H4 zinc finger CCCH-type containing 4
ZC3H7A zinc finger CCCH-type containing 7A
ZNF165 zinc finger protein 165
ZNF32 zinc finger protein 32
ZNF652 zinc finger protein 652
ZNF787 zinc finger protein 787
ZNF85 zinc finger protein 85
ZSCAN31 zinc finger and SCAN domain containing 31