trichostatin A-7047 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the trichostatin A-7047 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ADRB2 adrenoceptor beta 2, surface
AGTR1 angiotensin II receptor, type 1
ANGPTL4 angiopoietin-like 4
AQP3 aquaporin 3 (Gill blood group)
ARG2 arginase 2
ARHGAP26 Rho GTPase activating protein 26
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASMTL acetylserotonin O-methyltransferase-like
AVPI1 arginine vasopressin-induced 1
BAIAP2 BAI1-associated protein 2
BAMBI BMP and activin membrane-bound inhibitor
BIRC3 baculoviral IAP repeat containing 3
BMP6 bone morphogenetic protein 6
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLDN8 claudin 8
CORO1A coronin, actin binding protein, 1A
CPM carboxypeptidase M
CREB3L1 cAMP responsive element binding protein 3-like 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTGF connective tissue growth factor
DDIT4 DNA-damage-inducible transcript 4
DENND3 DENN/MADD domain containing 3
DEPTOR DEP domain containing MTOR-interacting protein
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DPYSL4 dihydropyrimidinase-like 4
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
EFNA3 ephrin-A3
ENOX1 ecto-NOX disulfide-thiol exchanger 1
EPHA4 EPH receptor A4
FABP4 fatty acid binding protein 4, adipocyte
FAM13A family with sequence similarity 13, member A
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FOS FBJ murine osteosarcoma viral oncogene homolog
GPRC5A G protein-coupled receptor, class C, group 5, member A
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOXA1 homeobox A1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IL11 interleukin 11
IL1RAP interleukin 1 receptor accessory protein
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
INSIG1 insulin induced gene 1
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIF5C kinesin family member 5C
LINC00312 long intergenic non-protein coding RNA 312
LMCD1 LIM and cysteine-rich domains 1
LPPR4 lipid phosphate phosphatase-related protein type 4
MAP1A microtubule-associated protein 1A
MAP2K3 mitogen-activated protein kinase kinase 3
MMP1 matrix metallopeptidase 1
MMP10 matrix metallopeptidase 10
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NID2 nidogen 2 (osteonidogen)
NR4A1 nuclear receptor subfamily 4, group A, member 1
OASL 2'-5'-oligoadenylate synthetase-like
PCDH17 protocadherin 17
PCDH9 protocadherin 9
PDE4DIP phosphodiesterase 4D interacting protein
PGPEP1 pyroglutamyl-peptidase I
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PKP2 plakophilin 2
PLK2 polo-like kinase 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RGCC regulator of cell cycle
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS4 regulator of G-protein signaling 4
RHOB ras homolog family member B
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SORBS1 sorbin and SH3 domain containing 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STC1 stanniocalcin 1
STK17B serine/threonine kinase 17b
STK4 serine/threonine kinase 4
STOM stomatin
SUN1 Sad1 and UNC84 domain containing 1
SYT1 synaptotagmin I
SYT11 synaptotagmin XI
TAOK3 TAO kinase 3
TESK2 testis-specific kinase 2
TJP3 tight junction protein 3
TRAFD1 TRAF-type zinc finger domain containing 1
TUBB2B tubulin, beta 2B class IIb
TUFT1 tuftelin 1
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
ADNP activity-dependent neuroprotector homeobox
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARSJ arylsulfatase family, member J
BAG2 BCL2-associated athanogene 2
BCAR3 breast cancer anti-estrogen resistance 3
CAPN15 calpain 15
CASD1 CAS1 domain containing 1
CBR3 carbonyl reductase 3
CCDC94 coiled-coil domain containing 94
CCNJ cyclin J
CLCF1 cardiotrophin-like cytokine factor 1
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CUL1 cullin 1
DEPDC1 DEP domain containing 1
E2F8 E2F transcription factor 8
FJX1 four jointed box 1 (Drosophila)
FOSL1 FOS-like antigen 1
FOXA1 forkhead box A1
FOXJ2 forkhead box J2
FST follistatin
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GABPB1 GA binding protein transcription factor, beta subunit 1
GBX2 gastrulation brain homeobox 2
GTF2IRD1 GTF2I repeat domain containing 1
H2AFY2 H2A histone family, member Y2
HAS2 hyaluronan synthase 2
HDAC7 histone deacetylase 7
HIRIP3 HIRA interacting protein 3
HMGA2 high mobility group AT-hook 2
HMGB3 high mobility group box 3
HOXA10 homeobox A10
IL33 interleukin 33
IL7R interleukin 7 receptor
INHBB inhibin, beta B
IPP intracisternal A particle-promoted polypeptide
ITPKB inositol-trisphosphate 3-kinase B
KAT6B K(lysine) acetyltransferase 6B
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KEAP1 kelch-like ECH-associated protein 1
LIF leukemia inhibitory factor
LMNB1 lamin B1
LPAR1 lysophosphatidic acid receptor 1
LRIF1 ligand dependent nuclear receptor interacting factor 1
LRRC37A3 leucine rich repeat containing 37, member A3
LUC7L2 LUC7-like 2 (S. cerevisiae)
MEPCE methylphosphate capping enzyme
METTL8 methyltransferase like 8
MEX3C mex-3 RNA binding family member C
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NNMT nicotinamide N-methyltransferase
NRIP1 nuclear receptor interacting protein 1
NUPR1 nuclear protein, transcriptional regulator, 1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PAGR1 PAXIP1 associated glutamate-rich protein 1
PALMD palmdelphin
PARP12 poly (ADP-ribose) polymerase family, member 12
POGK pogo transposable element with KRAB domain
PPAP2B phosphatidic acid phosphatase type 2B
PRSS16 protease, serine, 16 (thymus)
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RBM23 RNA binding motif protein 23
RIN2 Ras and Rab interactor 2
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SCAF8 SR-related CTD-associated factor 8
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SETD1B SET domain containing 1B
SETMAR SET domain and mariner transposase fusion gene
SFMBT1 Scm-like with four mbt domains 1
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SIDT1 SID1 transmembrane family, member 1
SMAGP small cell adhesion glycoprotein
SPHK1 sphingosine kinase 1
SRSF4 serine/arginine-rich splicing factor 4
SRSF8 serine/arginine-rich splicing factor 8
STAG1 stromal antigen 1
STX1A syntaxin 1A (brain)
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TACO1 translational activator of mitochondrially encoded cytochrome c oxidase I
TCEAL1 transcription elongation factor A (SII)-like 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TRIB3 tribbles pseudokinase 3
TRIM13 tripartite motif containing 13
TSSC4 tumor suppressing subtransferable candidate 4
URGCP upregulator of cell proliferation
VEGFC vascular endothelial growth factor C
XBP1 X-box binding protein 1
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial
ZBED1 zinc finger, BED-type containing 1
ZC3H4 zinc finger CCCH-type containing 4
ZNF165 zinc finger protein 165
ZNF532 zinc finger protein 532
ZNF692 zinc finger protein 692
ZNF787 zinc finger protein 787
ZNF804A zinc finger protein 804A
ZSCAN31 zinc finger and SCAN domain containing 31
ZZZ3 zinc finger, ZZ-type containing 3