trichostatin A-7005 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the trichostatin A-7005 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD6 abhydrolase domain containing 6
ACSF2 acyl-CoA synthetase family member 2
ADD3 adducin 3 (gamma)
ADM adrenomedullin
AHNAK2 AHNAK nucleoprotein 2
AKAP12 A kinase (PRKA) anchor protein 12
ALDOC aldolase C, fructose-bisphosphate
ARMCX2 armadillo repeat containing, X-linked 2
BAIAP2 BAI1-associated protein 2
BIK BCL2-interacting killer (apoptosis-inducing)
BMP7 bone morphogenetic protein 7
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BTN2A2 butyrophilin, subfamily 2, member A2
CD302 CD302 molecule
CDKL3 cyclin-dependent kinase-like 3
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CLGN calmegin
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSRP2 cysteine and glycine-rich protein 2
CXADR coxsackie virus and adenovirus receptor
CXCR4 chemokine (C-X-C motif) receptor 4
CYLD cylindromatosis (turban tumor syndrome)
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DEGS1 delta(4)-desaturase, sphingolipid 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DIXDC1 DIX domain containing 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DPYSL4 dihydropyrimidinase-like 4
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EFNB3 ephrin-B3
FKBP1B FK506 binding protein 1B, 12.6 kDa
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GEM GTP binding protein overexpressed in skeletal muscle
GLRX glutaredoxin (thioltransferase)
GLS glutaminase
GRK5 G protein-coupled receptor kinase 5
GTF2B general transcription factor IIB
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IRF6 interferon regulatory factor 6
KIAA0355 KIAA0355
KIAA0513 KIAA0513
KIF5C kinesin family member 5C
LIMA1 LIM domain and actin binding 1
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MLF1 myeloid leukemia factor 1
MMD monocyte to macrophage differentiation-associated
MXI1 MAX interactor 1, dimerization protein
MXRA7 matrix-remodelling associated 7
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NME7 NME/NM23 family member 7
NPC1 Niemann-Pick disease, type C1
NXN nucleoredoxin
OASL 2'-5'-oligoadenylate synthetase-like
PADI3 peptidyl arginine deiminase, type III
PDE4DIP phosphodiesterase 4D interacting protein
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PPARD peroxisome proliferator-activated receptor delta
PRPH peripherin
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTRF polymerase I and transcript release factor
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB40B RAB40B, member RAS oncogene family
RAI2 retinoic acid induced 2
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RTN2 reticulon 2
RUNDC3B RUN domain containing 3B
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPP1 selenoprotein P, plasma, 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH2B3 SH2B adaptor protein 3
SH3GL3 SH3-domain GRB2-like 3
SIRT4 sirtuin 4
SNN stannin
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STK17B serine/threonine kinase 17b
STON1 stonin 1
STXBP1 syntaxin binding protein 1
TMSB15A thymosin beta 15a
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TUBA4A tubulin, alpha 4a
TUBB2A tubulin, beta 2A class IIa
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
ULBP2 UL16 binding protein 2
UNC119 unc-119 homolog (C. elegans)
WDR19 WD repeat domain 19
WDR47 WD repeat domain 47
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF10 zinc finger protein 10
ZNF204P zinc finger protein 204, pseudogene

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADGRA3 adhesion G protein-coupled receptor A3
ADNP activity-dependent neuroprotector homeobox
AEN apoptosis enhancing nuclease
AKAP8 A kinase (PRKA) anchor protein 8
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
BAGE B melanoma antigen
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C11ORF68 chromosome 11 open reading frame 68
C9ORF91 chromosome 9 open reading frame 91
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CBR3 carbonyl reductase 3
CCDC170 coiled-coil domain containing 170
CCND1 cyclin D1
COA7 cytochrome c oxidase assembly factor 7 (putative)
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CUL1 cullin 1
CXCL12 chemokine (C-X-C motif) ligand 12
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
EGR3 early growth response 3
FAM57A family with sequence similarity 57, member A
FJX1 four jointed box 1 (Drosophila)
FOXA1 forkhead box A1
FOXC1 forkhead box C1
GABPB1 GA binding protein transcription factor, beta subunit 1
GATA3 GATA binding protein 3
GTF2I general transcription factor IIi
H2AFY2 H2A histone family, member Y2
HIRIP3 HIRA interacting protein 3
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
IRX5 iroquois homeobox 5
JADE1 jade family PHD finger 1
KEAP1 kelch-like ECH-associated protein 1
KIAA0753 KIAA0753
LAMA5 laminin, alpha 5
LMNB1 lamin B1
LOXL1 lysyl oxidase-like 1
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
LUC7L2 LUC7-like 2 (S. cerevisiae)
LY6G5C lymphocyte antigen 6 complex, locus G5C
MCM9 minichromosome maintenance complex component 9
MEPCE methylphosphate capping enzyme
METTL1 methyltransferase like 1
MLPH melanophilin
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MOCOS molybdenum cofactor sulfurase
MSL1 male-specific lethal 1 homolog (Drosophila)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCSTN nicastrin
NPY1R neuropeptide Y receptor Y1
NRIP1 nuclear receptor interacting protein 1
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PHLDA3 pleckstrin homology-like domain, family A, member 3
POGK pogo transposable element with KRAB domain
PPAN peter pan homolog (Drosophila)
PRR15L proline rich 15-like
PRR7 proline rich 7 (synaptic)
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM23 RNA binding motif protein 23
RWDD3 RWD domain containing 3
SCAF8 SR-related CTD-associated factor 8
SETD1B SET domain containing 1B
SFMBT1 Scm-like with four mbt domains 1
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
SLC35F2 solute carrier family 35, member F2
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SLTM SAFB-like, transcription modulator
SMAD7 SMAD family member 7
SMYD5 SMYD family member 5
SREK1 splicing regulatory glutamine/lysine-rich protein 1
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STC2 stanniocalcin 2
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TMEM30B transmembrane protein 30B
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TRIB3 tribbles pseudokinase 3
TRIM16 tripartite motif containing 16
TRIM8 tripartite motif containing 8
TSKU tsukushi, small leucine rich proteoglycan
UBL4A ubiquitin-like 4A
UBTF upstream binding transcription factor, RNA polymerase I
UBXN8 UBX domain protein 8
URGCP upregulator of cell proliferation
WDR43 WD repeat domain 43
WDR74 WD repeat domain 74
XBP1 X-box binding protein 1
YAP1 Yes-associated protein 1
ZC3H4 zinc finger CCCH-type containing 4
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1
ZNF33B zinc finger protein 33B