trichostatin A-6993 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the trichostatin A-6993 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ACSF2 acyl-CoA synthetase family member 2
AHNAK2 AHNAK nucleoprotein 2
AKAP12 A kinase (PRKA) anchor protein 12
ALDOC aldolase C, fructose-bisphosphate
ARMCX2 armadillo repeat containing, X-linked 2
BAIAP2 BAI1-associated protein 2
BAIAP3 BAI1-associated protein 3
CCDC28A coiled-coil domain containing 28A
CCNA1 cyclin A1
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CLGN calmegin
CLMN calmin (calponin-like, transmembrane)
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSRP2 cysteine and glycine-rich protein 2
CXADR coxsackie virus and adenovirus receptor
CYLD cylindromatosis (turban tumor syndrome)
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DPYSL4 dihydropyrimidinase-like 4
EFNA3 ephrin-A3
EFNB3 ephrin-B3
EGR1 early growth response 1
ELOVL4 ELOVL fatty acid elongase 4
FKBP1B FK506 binding protein 1B, 12.6 kDa
FN1 fibronectin 1
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GCHFR GTP cyclohydrolase I feedback regulator
GEM GTP binding protein overexpressed in skeletal muscle
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GLCE glucuronic acid epimerase
GLRX glutaredoxin (thioltransferase)
GLS glutaminase
GRK5 G protein-coupled receptor kinase 5
GTF2B general transcription factor IIB
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HSPA2 heat shock 70kDa protein 2
IRF6 interferon regulatory factor 6
IRF7 interferon regulatory factor 7
KIAA0513 KIAA0513
KIF13B kinesin family member 13B
KIF5C kinesin family member 5C
LIMA1 LIM domain and actin binding 1
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MAPT microtubule-associated protein tau
MAST3 microtubule associated serine/threonine kinase 3
MLF1 myeloid leukemia factor 1
MMD monocyte to macrophage differentiation-associated
NES nestin
NME5 NME/NM23 family member 5
NPC1 Niemann-Pick disease, type C1
NXN nucleoredoxin
OASL 2'-5'-oligoadenylate synthetase-like
PADI3 peptidyl arginine deiminase, type III
PAIP2B poly(A) binding protein interacting protein 2B
PARP16 poly (ADP-ribose) polymerase family, member 16
PCDH9 protocadherin 9
PDE4DIP phosphodiesterase 4D interacting protein
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PMEL premelanosome protein
PPARD peroxisome proliferator-activated receptor delta
PRPH peripherin
PTRF polymerase I and transcript release factor
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB40B RAB40B, member RAS oncogene family
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
RIPK4 receptor-interacting serine-threonine kinase 4
RPL3L ribosomal protein L3-like
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RTN2 reticulon 2
RUNDC3B RUN domain containing 3B
SEPP1 selenoprotein P, plasma, 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SIRT4 sirtuin 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC26A2 solute carrier family 26 (anion exchanger), member 2
STXBP1 syntaxin binding protein 1
SYT11 synaptotagmin XI
TMSB15A thymosin beta 15a
TRIM2 tripartite motif containing 2
TUBB2A tubulin, beta 2A class IIa
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
ULBP2 UL16 binding protein 2
WDR19 WD repeat domain 19
WDR47 WD repeat domain 47
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZCCHC24 zinc finger, CCHC domain containing 24
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF10 zinc finger protein 10
ZNF204P zinc finger protein 204, pseudogene

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADNP activity-dependent neuroprotector homeobox
AMIGO2 adhesion molecule with Ig-like domain 2
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BCAR3 breast cancer anti-estrogen resistance 3
C9ORF91 chromosome 9 open reading frame 91
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CBR3 carbonyl reductase 3
CCDC94 coiled-coil domain containing 94
CCND1 cyclin D1
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CXCL12 chemokine (C-X-C motif) ligand 12
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP4 dual specificity phosphatase 4
E2F3 E2F transcription factor 3
EFNA1 ephrin-A1
EGR3 early growth response 3
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
ERBB2IP erbb2 interacting protein
ESRP2 epithelial splicing regulatory protein 2
FAM57A family with sequence similarity 57, member A
FJX1 four jointed box 1 (Drosophila)
FOXA1 forkhead box A1
FOXD1 forkhead box D1
GABPB1 GA binding protein transcription factor, beta subunit 1
GATA3 GATA binding protein 3
GTF2I general transcription factor IIi
H2AFY2 H2A histone family, member Y2
HIRIP3 HIRA interacting protein 3
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HOXC11 homeobox C11
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
IRX5 iroquois homeobox 5
KCNK1 potassium channel, two pore domain subfamily K, member 1
KCTD15 potassium channel tetramerization domain containing 15
KEAP1 kelch-like ECH-associated protein 1
KIAA0125 KIAA0125
LMNB1 lamin B1
LUC7L2 LUC7-like 2 (S. cerevisiae)
MEPCE methylphosphate capping enzyme
METTL8 methyltransferase like 8
MSL1 male-specific lethal 1 homolog (Drosophila)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
NMI N-myc (and STAT) interactor
NPY1R neuropeptide Y receptor Y1
NR1H2 nuclear receptor subfamily 1, group H, member 2
NRIP1 nuclear receptor interacting protein 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PCNT pericentrin
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PHLDA3 pleckstrin homology-like domain, family A, member 3
PLK1 polo-like kinase 1
POGK pogo transposable element with KRAB domain
PRNP prion protein
PRR15L proline rich 15-like
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM23 RNA binding motif protein 23
RGS19 regulator of G-protein signaling 19
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SETD1B SET domain containing 1B
SFMBT1 Scm-like with four mbt domains 1
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC35F2 solute carrier family 35, member F2
SMAD7 SMAD family member 7
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SRSF4 serine/arginine-rich splicing factor 4
SRSF8 serine/arginine-rich splicing factor 8
STBD1 starch binding domain 1
STC2 stanniocalcin 2
TGIF1 TGFB-induced factor homeobox 1
TMEM30B transmembrane protein 30B
TRAF5 TNF receptor-associated factor 5
TRIB3 tribbles pseudokinase 3
TRIM16 tripartite motif containing 16
TRIM8 tripartite motif containing 8
TRPS1 trichorhinophalangeal syndrome I
TSKU tsukushi, small leucine rich proteoglycan
TSSC4 tumor suppressing subtransferable candidate 4
UBL4A ubiquitin-like 4A
UBTF upstream binding transcription factor, RNA polymerase I
UCK2 uridine-cytidine kinase 2
USP21 ubiquitin specific peptidase 21
XBP1 X-box binding protein 1
ZC3H4 zinc finger CCCH-type containing 4
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1
ZNF253 zinc finger protein 253
ZNF32 zinc finger protein 32
ZNF408 zinc finger protein 408
ZNF692 zinc finger protein 692