trichostatin A-6972 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the trichostatin A-6972 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
ADD3 adducin 3 (gamma)
ADM adrenomedullin
AHNAK2 AHNAK nucleoprotein 2
ALDOC aldolase C, fructose-bisphosphate
ARL4D ADP-ribosylation factor-like 4D
ARMCX2 armadillo repeat containing, X-linked 2
CCDC28A coiled-coil domain containing 28A
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CLGN calmegin
CLMN calmin (calponin-like, transmembrane)
CORO1A coronin, actin binding protein, 1A
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSRP2 cysteine and glycine-rich protein 2
CTNS cystinosin, lysosomal cystine transporter
CXADR coxsackie virus and adenovirus receptor
CXCR4 chemokine (C-X-C motif) receptor 4
CYLD cylindromatosis (turban tumor syndrome)
DEGS1 delta(4)-desaturase, sphingolipid 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLX2 distal-less homeobox 2
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DPYSL4 dihydropyrimidinase-like 4
EFNA3 ephrin-A3
EFNB3 ephrin-B3
ELOVL4 ELOVL fatty acid elongase 4
EPOR erythropoietin receptor
FAM105A family with sequence similarity 105, member A
FAM46C family with sequence similarity 46, member C
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GEM GTP binding protein overexpressed in skeletal muscle
GLRX glutaredoxin (thioltransferase)
GLS glutaminase
GRK5 G protein-coupled receptor kinase 5
GSDMB gasdermin B
GTF2B general transcription factor IIB
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HSPA2 heat shock 70kDa protein 2
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
KIAA0513 KIAA0513
KIF5C kinesin family member 5C
LARP6 La ribonucleoprotein domain family, member 6
LIMA1 LIM domain and actin binding 1
LYST lysosomal trafficking regulator
MAP1B microtubule-associated protein 1B
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MCOLN1 mucolipin 1
MLF1 myeloid leukemia factor 1
MMD monocyte to macrophage differentiation-associated
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NME5 NME/NM23 family member 5
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NXN nucleoredoxin
NXPE3 neurexophilin and PC-esterase domain family, member 3
OASL 2'-5'-oligoadenylate synthetase-like
PADI3 peptidyl arginine deiminase, type III
PAIP2B poly(A) binding protein interacting protein 2B
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDE4DIP phosphodiesterase 4D interacting protein
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PLAC1 placenta-specific 1
PPARD peroxisome proliferator-activated receptor delta
PRPH peripherin
PTCH1 patched 1
RAB40B RAB40B, member RAS oncogene family
REEP1 receptor accessory protein 1
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RTN2 reticulon 2
RUNDC3B RUN domain containing 3B
SEPP1 selenoprotein P, plasma, 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SFXN3 sideroflexin 3
SH3GL3 SH3-domain GRB2-like 3
SLC26A2 solute carrier family 26 (anion exchanger), member 2
STK17A serine/threonine kinase 17a
STON1 stonin 1
STX12 syntaxin 12
STXBP1 syntaxin binding protein 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
TACC1 transforming, acidic coiled-coil containing protein 1
TBXA2R thromboxane A2 receptor
TMSB15A thymosin beta 15a
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TRIM2 tripartite motif containing 2
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
ULBP2 UL16 binding protein 2
WDR19 WD repeat domain 19
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZCCHC24 zinc finger, CCHC domain containing 24
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF204P zinc finger protein 204, pseudogene

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADGRA3 adhesion G protein-coupled receptor A3
ADNP activity-dependent neuroprotector homeobox
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BCAR3 breast cancer anti-estrogen resistance 3
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C2CD5 C2 calcium-dependent domain containing 5
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCDC94 coiled-coil domain containing 94
CCND1 cyclin D1
CDK5RAP2 CDK5 regulatory subunit associated protein 2
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CTPS1 CTP synthase 1
CUL1 cullin 1
CXCL12 chemokine (C-X-C motif) ligand 12
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
EFCAB2 EF-hand calcium binding domain 2
EGR3 early growth response 3
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
ESRP2 epithelial splicing regulatory protein 2
FAIM Fas apoptotic inhibitory molecule
FAM57A family with sequence similarity 57, member A
FHOD1 formin homology 2 domain containing 1
FJX1 four jointed box 1 (Drosophila)
FOXC1 forkhead box C1
GABPB1 GA binding protein transcription factor, beta subunit 1
GTF2I general transcription factor IIi
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
IRX5 iroquois homeobox 5
KCTD15 potassium channel tetramerization domain containing 15
KEAP1 kelch-like ECH-associated protein 1
KIAA0125 KIAA0125
KIAA0753 KIAA0753
LMNB1 lamin B1
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
LY6G5C lymphocyte antigen 6 complex, locus G5C
MCRS1 microspherule protein 1
MED22 mediator complex subunit 22
MEPCE methylphosphate capping enzyme
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MSL1 male-specific lethal 1 homolog (Drosophila)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
NABP2 nucleic acid binding protein 2
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NCOA6 nuclear receptor coactivator 6
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NPY1R neuropeptide Y receptor Y1
NR1D2 nuclear receptor subfamily 1, group D, member 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
NRIP1 nuclear receptor interacting protein 1
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
NUAK1 NUAK family, SNF1-like kinase, 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PCBP1 poly(rC) binding protein 1
PCNT pericentrin
POGK pogo transposable element with KRAB domain
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRNP prion protein
PUS1 pseudouridylate synthase 1
QRICH1 glutamine-rich 1
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM23 RNA binding motif protein 23
RHOBTB1 Rho-related BTB domain containing 1
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SIDT1 SID1 transmembrane family, member 1
SLTM SAFB-like, transcription modulator
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SRSF4 serine/arginine-rich splicing factor 4
SRSF8 serine/arginine-rich splicing factor 8
STC2 stanniocalcin 2
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
THAP4 THAP domain containing 4
THEM6 thioesterase superfamily member 6
TOE1 target of EGR1, member 1 (nuclear)
TRAF5 TNF receptor-associated factor 5
TRIB3 tribbles pseudokinase 3
TRIM8 tripartite motif containing 8
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae)
TRPS1 trichorhinophalangeal syndrome I
TSKU tsukushi, small leucine rich proteoglycan
UBTF upstream binding transcription factor, RNA polymerase I
UBXN8 UBX domain protein 8
VRK2 vaccinia related kinase 2
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
XBP1 X-box binding protein 1
ZBTB38 zinc finger and BTB domain containing 38
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1
ZNF33B zinc finger protein 33B
ZNF692 zinc finger protein 692
ZZZ3 zinc finger, ZZ-type containing 3