trichostatin A-6891 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the trichostatin A-6891 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
AHNAK2 AHNAK nucleoprotein 2
AKAP12 A kinase (PRKA) anchor protein 12
ARMCX2 armadillo repeat containing, X-linked 2
BAIAP2 BAI1-associated protein 2
BAIAP3 BAI1-associated protein 3
CALCOCO1 calcium binding and coiled-coil domain 1
CCDC28A coiled-coil domain containing 28A
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CLGN calmegin
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CXADR coxsackie virus and adenovirus receptor
CYLD cylindromatosis (turban tumor syndrome)
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DFNB31 deafness, autosomal recessive 31
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DPYSL4 dihydropyrimidinase-like 4
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFNA3 ephrin-A3
EFNB3 ephrin-B3
ELOVL4 ELOVL fatty acid elongase 4
EPOR erythropoietin receptor
FAM214B family with sequence similarity 214, member B
FKBP1B FK506 binding protein 1B, 12.6 kDa
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GEM GTP binding protein overexpressed in skeletal muscle
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GLCE glucuronic acid epimerase
GLDC glycine dehydrogenase (decarboxylating)
GLRX glutaredoxin (thioltransferase)
GRAMD1C GRAM domain containing 1C
GRK5 G protein-coupled receptor kinase 5
GSDMB gasdermin B
GTF2B general transcription factor IIB
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IFI6 interferon, alpha-inducible protein 6
KIF13B kinesin family member 13B
KIF21B kinesin family member 21B
LIMA1 LIM domain and actin binding 1
LTB4R leukotriene B4 receptor
LYST lysosomal trafficking regulator
MAP1B microtubule-associated protein 1B
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MARK4 MAP/microtubule affinity-regulating kinase 4
MAST3 microtubule associated serine/threonine kinase 3
MLF1 myeloid leukemia factor 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NKX3-1 NK3 homeobox 1
NME5 NME/NM23 family member 5
NPC1 Niemann-Pick disease, type C1
NXN nucleoredoxin
OASL 2'-5'-oligoadenylate synthetase-like
PAIP2B poly(A) binding protein interacting protein 2B
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDE4A phosphodiesterase 4A, cAMP-specific
PER1 period circadian clock 1
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PMEL premelanosome protein
PRPH peripherin
RAI2 retinoic acid induced 2
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
RIPK4 receptor-interacting serine-threonine kinase 4
RPL3L ribosomal protein L3-like
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RUNDC3B RUN domain containing 3B
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPP1 selenoprotein P, plasma, 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SIRT4 sirtuin 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
STK17A serine/threonine kinase 17a
STON1 stonin 1
STX2 syntaxin 2
SYT11 synaptotagmin XI
TBXA2R thromboxane A2 receptor
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TTBK2 tau tubulin kinase 2
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
ULBP2 UL16 binding protein 2
WDR19 WD repeat domain 19
WDR47 WD repeat domain 47
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZCCHC24 zinc finger, CCHC domain containing 24
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF10 zinc finger protein 10
ZNF204P zinc finger protein 204, pseudogene
ZNF778 zinc finger protein 778

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADGRA3 adhesion G protein-coupled receptor A3
ADNP activity-dependent neuroprotector homeobox
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
AMIGO2 adhesion molecule with Ig-like domain 2
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARTN artemin
ATAD2B ATPase family, AAA domain containing 2B
BANP BTG3 associated nuclear protein
BATF basic leucine zipper transcription factor, ATF-like
BCAR3 breast cancer anti-estrogen resistance 3
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CBR3 carbonyl reductase 3
CCDC170 coiled-coil domain containing 170
CCDC94 coiled-coil domain containing 94
CCND1 cyclin D1
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CHKB choline kinase beta
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CTPS1 CTP synthase 1
CUEDC1 CUE domain containing 1
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DKK1 dickkopf WNT signaling pathway inhibitor 1
EFNA1 ephrin-A1
EGR3 early growth response 3
ESRP2 epithelial splicing regulatory protein 2
FAM155B family with sequence similarity 155, member B
FAM57A family with sequence similarity 57, member A
FJX1 four jointed box 1 (Drosophila)
FOXA1 forkhead box A1
FOXC1 forkhead box C1
FOXJ2 forkhead box J2
GABPB1 GA binding protein transcription factor, beta subunit 1
GATA3 GATA binding protein 3
GATA4 GATA binding protein 4
GTF2IRD1 GTF2I repeat domain containing 1
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HOXC11 homeobox C11
IL15RA interleukin 15 receptor, alpha
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
IRX5 iroquois homeobox 5
KCTD15 potassium channel tetramerization domain containing 15
KEAP1 kelch-like ECH-associated protein 1
KIAA0125 KIAA0125
LMNB1 lamin B1
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LY6G5C lymphocyte antigen 6 complex, locus G5C
MCM9 minichromosome maintenance complex component 9
MEPCE methylphosphate capping enzyme
METTL8 methyltransferase like 8
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MSL1 male-specific lethal 1 homolog (Drosophila)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
NPY1R neuropeptide Y receptor Y1
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRIP1 nuclear receptor interacting protein 1
NSD1 nuclear receptor binding SET domain protein 1
NUAK1 NUAK family, SNF1-like kinase, 1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PHLDA3 pleckstrin homology-like domain, family A, member 3
PLK1 polo-like kinase 1
POGK pogo transposable element with KRAB domain
PPAN peter pan homolog (Drosophila)
PRR15L proline rich 15-like
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM23 RNA binding motif protein 23
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SETD1B SET domain containing 1B
SFMBT1 Scm-like with four mbt domains 1
SLC35F2 solute carrier family 35, member F2
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMAD7 SMAD family member 7
SMG9 SMG9 nonsense mediated mRNA decay factor
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SRSF4 serine/arginine-rich splicing factor 4
STC2 stanniocalcin 2
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TGIF1 TGFB-induced factor homeobox 1
TNS2 tensin 2
TOE1 target of EGR1, member 1 (nuclear)
TRAF5 TNF receptor-associated factor 5
TRIB3 tribbles pseudokinase 3
TSKU tsukushi, small leucine rich proteoglycan
VRK2 vaccinia related kinase 2
VWA9 von Willebrand factor A domain containing 9
XBP1 X-box binding protein 1
ZBED1 zinc finger, BED-type containing 1
ZC3H4 zinc finger CCCH-type containing 4
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF573 zinc finger protein 573
ZNF692 zinc finger protein 692
ZNHIT2 zinc finger, HIT-type containing 2