trichostatin A-6886 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the trichostatin A-6886 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACSBG1 acyl-CoA synthetase bubblegum family member 1
AGTR1 angiotensin II receptor, type 1
AK2 adenylate kinase 2
ANGPTL4 angiopoietin-like 4
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AQP3 aquaporin 3 (Gill blood group)
ARG2 arginase 2
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ATM ATM serine/threonine kinase
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
BAMBI BMP and activin membrane-bound inhibitor
BMP6 bone morphogenetic protein 6
C16ORF45 chromosome 16 open reading frame 45
C4ORF29 chromosome 4 open reading frame 29
C8ORF60 chromosome 8 open reading frame 60
CA2 carbonic anhydrase II
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CFAP69 cilia and flagella associated protein 69
CHMP1B charged multivesicular body protein 1B
CNN2 calponin 2
CORO1A coronin, actin binding protein, 1A
CPM carboxypeptidase M
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CTGF connective tissue growth factor
CTH cystathionine gamma-lyase
CXCR4 chemokine (C-X-C motif) receptor 4
CYR61 cysteine-rich, angiogenic inducer, 61
DBP D site of albumin promoter (albumin D-box) binding protein
DBT dihydrolipoamide branched chain transacylase E2
DENND3 DENN/MADD domain containing 3
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EPPK1 epiplakin 1
F11R F11 receptor
FABP4 fatty acid binding protein 4, adipocyte
FKBP14 FK506 binding protein 14, 22 kDa
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GADD45B growth arrest and DNA-damage-inducible, beta
GINS4 GINS complex subunit 4 (Sld5 homolog)
GK glycerol kinase
GLTP glycolipid transfer protein
GM2A GM2 ganglioside activator
GMPR guanosine monophosphate reductase
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HIRA histone cell cycle regulator
HMOX1 heme oxygenase 1
HSPA2 heat shock 70kDa protein 2
ICAM1 intercellular adhesion molecule 1
IFT22 intraflagellar transport 22
INSIG1 insulin induced gene 1
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
LDLR low density lipoprotein receptor
LMCD1 LIM and cysteine-rich domains 1
LRRC40 leucine rich repeat containing 40
MAK male germ cell-associated kinase
MAPT microtubule-associated protein tau
MMP16 matrix metallopeptidase 16 (membrane-inserted)
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEU1 sialidase 1 (lysosomal sialidase)
OASL 2'-5'-oligoadenylate synthetase-like
PDE4DIP phosphodiesterase 4D interacting protein
PDLIM5 PDZ and LIM domain 5
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB3B RAB3B, member RAS oncogene family
RAI2 retinoic acid induced 2
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS4 regulator of G-protein signaling 4
RIOK3 RIO kinase 3
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPL23AP32 ribosomal protein L23a pseudogene 32
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SOX15 SRY (sex determining region Y)-box 15
STC1 stanniocalcin 1
STK17B serine/threonine kinase 17b
STK4 serine/threonine kinase 4
SUN1 Sad1 and UNC84 domain containing 1
SYT1 synaptotagmin I
SYT11 synaptotagmin XI
SYTL2 synaptotagmin-like 2
TAOK3 TAO kinase 3
TUBB2B tubulin, beta 2B class IIb
TUBD1 tubulin, delta 1
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
USP2 ubiquitin specific peptidase 2
WSB1 WD repeat and SOCS box containing 1
YIPF5 Yip1 domain family, member 5
ZC3H12A zinc finger CCCH-type containing 12A
ZFP36 ZFP36 ring finger protein
ZNF277 zinc finger protein 277
ZNF510 zinc finger protein 510
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ADNP activity-dependent neuroprotector homeobox
AFAP1 actin filament associated protein 1
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARSJ arylsulfatase family, member J
BAG2 BCL2-associated athanogene 2
BCAR3 breast cancer anti-estrogen resistance 3
BHLHE41 basic helix-loop-helix family, member e41
C7ORF49 chromosome 7 open reading frame 49
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CBR3 carbonyl reductase 3
CDC7 cell division cycle 7
CLCF1 cardiotrophin-like cytokine factor 1
CLIP1 CAP-GLY domain containing linker protein 1
CTCF CCCTC-binding factor (zinc finger protein)
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
DCLRE1A DNA cross-link repair 1A
DENND1B DENN/MADD domain containing 1B
DEPDC1 DEP domain containing 1
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
E2F8 E2F transcription factor 8
EHF ets homologous factor
ERBB2IP erbb2 interacting protein
FAM169A family with sequence similarity 169, member A
FAM57A family with sequence similarity 57, member A
FGD1 FYVE, RhoGEF and PH domain containing 1
FJX1 four jointed box 1 (Drosophila)
FOSL1 FOS-like antigen 1
FOXA1 forkhead box A1
FOXD1 forkhead box D1
FPGS folylpolyglutamate synthase
FST follistatin
FZD6 frizzled class receptor 6
GLTSCR1L GLTSCR1-like
GRPR gastrin-releasing peptide receptor
H2AFY2 H2A histone family, member Y2
HAS2 hyaluronan synthase 2
HDAC9 histone deacetylase 9
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HIRIP3 HIRA interacting protein 3
HMGA2 high mobility group AT-hook 2
HMGXB4 HMG box domain containing 4
IL7R interleukin 7 receptor
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
KEAP1 kelch-like ECH-associated protein 1
KIAA0753 KIAA0753
KRT15 keratin 15, type I
LIF leukemia inhibitory factor
LMNB1 lamin B1
LPAR1 lysophosphatidic acid receptor 1
LRIF1 ligand dependent nuclear receptor interacting factor 1
LUC7L2 LUC7-like 2 (S. cerevisiae)
MANEA mannosidase, endo-alpha
MELK maternal embryonic leucine zipper kinase
MEPCE methylphosphate capping enzyme
MGA MGA, MAX dimerization protein
MKS1 Meckel syndrome, type 1
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MSL1 male-specific lethal 1 homolog (Drosophila)
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NLRX1 NLR family member X1
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae)
NR2F1 nuclear receptor subfamily 2, group F, member 1
NRIP1 nuclear receptor interacting protein 1
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
PEF1 penta-EF-hand domain containing 1
PHF11 PHD finger protein 11
PLAU plasminogen activator, urokinase
PPAP2B phosphatidic acid phosphatase type 2B
RBM23 RNA binding motif protein 23
RGS19 regulator of G-protein signaling 19
RIN2 Ras and Rab interactor 2
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SMAGP small cell adhesion glycoprotein
SRSF4 serine/arginine-rich splicing factor 4
ST5 suppression of tumorigenicity 5
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TGFB3 transforming growth factor, beta 3
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TRIB3 tribbles pseudokinase 3
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPM2 transient receptor potential cation channel, subfamily M, member 2
VEGFC vascular endothelial growth factor C
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
VWA9 von Willebrand factor A domain containing 9
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial
ZBED1 zinc finger, BED-type containing 1
ZC3H4 zinc finger CCCH-type containing 4
ZNF165 zinc finger protein 165
ZNF189 zinc finger protein 189
ZNF248 zinc finger protein 248
ZNF302 zinc finger protein 302
ZNF33B zinc finger protein 33B
ZNF532 zinc finger protein 532
ZNHIT2 zinc finger, HIT-type containing 2