trichostatin A-6874 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the trichostatin A-6874 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ACSBG1 acyl-CoA synthetase bubblegum family member 1
AGTR1 angiotensin II receptor, type 1
ANGPTL4 angiopoietin-like 4
AQP3 aquaporin 3 (Gill blood group)
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASMTL acetylserotonin O-methyltransferase-like
ATP11A ATPase, class VI, type 11A
AVPI1 arginine vasopressin-induced 1
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BAIAP2 BAI1-associated protein 2
BAMBI BMP and activin membrane-bound inhibitor
C1QL1 complement component 1, q subcomponent-like 1
C22ORF29 chromosome 22 open reading frame 29
CA5B carbonic anhydrase VB, mitochondrial
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEP112 centrosomal protein 112kDa
CEP68 centrosomal protein 68kDa
CFAP69 cilia and flagella associated protein 69
CORO1A coronin, actin binding protein, 1A
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTGF connective tissue growth factor
CTH cystathionine gamma-lyase
CYR61 cysteine-rich, angiogenic inducer, 61
DALRD3 DALR anticodon binding domain containing 3
DBP D site of albumin promoter (albumin D-box) binding protein
DENND3 DENN/MADD domain containing 3
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DPF3 D4, zinc and double PHD fingers, family 3
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
EPHB3 EPH receptor B3
EPPK1 epiplakin 1
F3 coagulation factor III (thromboplastin, tissue factor)
FABP4 fatty acid binding protein 4, adipocyte
GADD45B growth arrest and DNA-damage-inducible, beta
GFOD2 glucose-fructose oxidoreductase domain containing 2
GK glycerol kinase
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HOXA1 homeobox A1
HSPA2 heat shock 70kDa protein 2
IL11 interleukin 11
IL1RAP interleukin 1 receptor accessory protein
INSIG1 insulin induced gene 1
IRF6 interferon regulatory factor 6
ISYNA1 inositol-3-phosphate synthase 1
KIF5C kinesin family member 5C
MAP2 microtubule-associated protein 2
MAPT microtubule-associated protein tau
MBD1 methyl-CpG binding domain protein 1
MLF1 myeloid leukemia factor 1
MMP10 matrix metallopeptidase 10
MSX2 msh homeobox 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
OASL 2'-5'-oligoadenylate synthetase-like
PCDH9 protocadherin 9
PDE4DIP phosphodiesterase 4D interacting protein
PDLIM5 PDZ and LIM domain 5
PEX16 peroxisomal biogenesis factor 16
PLA2G15 phospholipase A2, group XV
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLLP plasmolipin
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PRDM2 PR domain containing 2, with ZNF domain
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB8B RAB8B, member RAS oncogene family
RAI2 retinoic acid induced 2
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RND1 Rho family GTPase 1
ROM1 retinal outer segment membrane protein 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SKI SKI proto-oncogene
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SPTAN1 spectrin, alpha, non-erythrocytic 1
SQSTM1 sequestosome 1
STC1 stanniocalcin 1
STK17B serine/threonine kinase 17b
SYT1 synaptotagmin I
SYT11 synaptotagmin XI
SYTL2 synaptotagmin-like 2
TJP3 tight junction protein 3
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TUBB2B tubulin, beta 2B class IIb
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
UBE2H ubiquitin-conjugating enzyme E2H
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
ZNF277 zinc finger protein 277

decreased expression

Symbol Name
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADNP activity-dependent neuroprotector homeobox
AFAP1 actin filament associated protein 1
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARSJ arylsulfatase family, member J
BAG2 BCL2-associated athanogene 2
BCAR3 breast cancer anti-estrogen resistance 3
BHLHE41 basic helix-loop-helix family, member e41
C10ORF88 chromosome 10 open reading frame 88
C1ORF216 chromosome 1 open reading frame 216
CASD1 CAS1 domain containing 1
CBR3 carbonyl reductase 3
CDT1 chromatin licensing and DNA replication factor 1
CHKB choline kinase beta
CTCF CCCTC-binding factor (zinc finger protein)
CUL1 cullin 1
CUTC cutC copper transporter
DEPDC1 DEP domain containing 1
DRAM1 DNA-damage regulated autophagy modulator 1
E2F8 E2F transcription factor 8
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
ERAP2 endoplasmic reticulum aminopeptidase 2
FADD Fas (TNFRSF6)-associated via death domain
FAM114A2 family with sequence similarity 114, member A2
FAM169A family with sequence similarity 169, member A
FAM57A family with sequence similarity 57, member A
FJX1 four jointed box 1 (Drosophila)
FOSL1 FOS-like antigen 1
FOXA1 forkhead box A1
GPR87 G protein-coupled receptor 87
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HAS2 hyaluronan synthase 2
HEATR3 HEAT repeat containing 3
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HMG20A high mobility group 20A
HMGA2 high mobility group AT-hook 2
IL7R interleukin 7 receptor
INHBB inhibin, beta B
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KEAP1 kelch-like ECH-associated protein 1
LIF leukemia inhibitory factor
LMNB1 lamin B1
LPAR1 lysophosphatidic acid receptor 1
LRIF1 ligand dependent nuclear receptor interacting factor 1
LUC7L2 LUC7-like 2 (S. cerevisiae)
MANSC1 MANSC domain containing 1
MEPCE methylphosphate capping enzyme
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MSL1 male-specific lethal 1 homolog (Drosophila)
NDC80 NDC80 kinetochore complex component
NMI N-myc (and STAT) interactor
NRIP1 nuclear receptor interacting protein 1
NTSR1 neurotensin receptor 1 (high affinity)
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
NUP62 nucleoporin 62kDa
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PARP12 poly (ADP-ribose) polymerase family, member 12
PLAU plasminogen activator, urokinase
POLL polymerase (DNA directed), lambda
PPAP2B phosphatidic acid phosphatase type 2B
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RBM4B RNA binding motif protein 4B
RIN2 Ras and Rab interactor 2
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SETD1B SET domain containing 1B
SIDT1 SID1 transmembrane family, member 1
SIM2 single-minded family bHLH transcription factor 2
SKA1 spindle and kinetochore associated complex subunit 1
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SMAGP small cell adhesion glycoprotein
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SPHK1 sphingosine kinase 1
SRSF4 serine/arginine-rich splicing factor 4
STBD1 starch binding domain 1
SYNPO synaptopodin
TACO1 translational activator of mitochondrially encoded cytochrome c oxidase I
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TOE1 target of EGR1, member 1 (nuclear)
TOR3A torsin family 3, member A
TRAF5 TNF receptor-associated factor 5
TRIB3 tribbles pseudokinase 3
TRIM13 tripartite motif containing 13
TRIM5 tripartite motif containing 5
TRIM8 tripartite motif containing 8
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
USP21 ubiquitin specific peptidase 21
VEGFC vascular endothelial growth factor C
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
VWA9 von Willebrand factor A domain containing 9
WDR82 WD repeat domain 82
WNT7A wingless-type MMTV integration site family, member 7A
ZBED1 zinc finger, BED-type containing 1
ZC3H4 zinc finger CCCH-type containing 4
ZNF112 zinc finger protein 112
ZNF32 zinc finger protein 32
ZNF532 zinc finger protein 532
ZNF573 zinc finger protein 573
ZZZ3 zinc finger, ZZ-type containing 3