trichostatin A-6820 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the trichostatin A-6820 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADD3 adducin 3 (gamma)
ADM adrenomedullin
AHNAK2 AHNAK nucleoprotein 2
AKAP12 A kinase (PRKA) anchor protein 12
ALDOC aldolase C, fructose-bisphosphate
ANG angiogenin, ribonuclease, RNase A family, 5
ARMCX2 armadillo repeat containing, X-linked 2
BEX4 brain expressed, X-linked 4
CASC1 cancer susceptibility candidate 1
CCDC68 coiled-coil domain containing 68
CCNA1 cyclin A1
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEP112 centrosomal protein 112kDa
CLGN calmegin
CORO1A coronin, actin binding protein, 1A
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTGF connective tissue growth factor
CXADR coxsackie virus and adenovirus receptor
CXCR4 chemokine (C-X-C motif) receptor 4
CYLD cylindromatosis (turban tumor syndrome)
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
EFNA3 ephrin-A3
EFNB3 ephrin-B3
ELL2 elongation factor, RNA polymerase II, 2
ELOVL4 ELOVL fatty acid elongase 4
EPOR erythropoietin receptor
FAM105A family with sequence similarity 105, member A
FAM214B family with sequence similarity 214, member B
FKBP1B FK506 binding protein 1B, 12.6 kDa
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GEM GTP binding protein overexpressed in skeletal muscle
GLDC glycine dehydrogenase (decarboxylating)
GLRX glutaredoxin (thioltransferase)
GRAMD1C GRAM domain containing 1C
GTF2B general transcription factor IIB
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
HYAL1 hyaluronoglucosaminidase 1
IL1RAP interleukin 1 receptor accessory protein
ITM2C integral membrane protein 2C
LIMA1 LIM domain and actin binding 1
MAP1B microtubule-associated protein 1B
MAPK14 mitogen-activated protein kinase 14
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MCOLN1 mucolipin 1
MLF1 myeloid leukemia factor 1
NAP1L3 nucleosome assembly protein 1-like 3
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NXN nucleoredoxin
PADI3 peptidyl arginine deiminase, type III
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDE4DIP phosphodiesterase 4D interacting protein
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PLLP plasmolipin
PRPH peripherin
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
RAB3B RAB3B, member RAS oncogene family
RAI2 retinoic acid induced 2
RGCC regulator of cell cycle
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
RND1 Rho family GTPase 1
RPL3L ribosomal protein L3-like
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RTN2 reticulon 2
RUNDC3B RUN domain containing 3B
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPP1 selenoprotein P, plasma, 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SIRT4 sirtuin 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SORBS1 sorbin and SH3 domain containing 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STON1 stonin 1
SYBU syntabulin (syntaxin-interacting)
SYT11 synaptotagmin XI
TBXA2R thromboxane A2 receptor
TIMP3 TIMP metallopeptidase inhibitor 3
TRIM36 tripartite motif containing 36
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
ULBP2 UL16 binding protein 2
WDR19 WD repeat domain 19
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZBTB18 zinc finger and BTB domain containing 18
ZCCHC24 zinc finger, CCHC domain containing 24
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF10 zinc finger protein 10
ZNF204P zinc finger protein 204, pseudogene

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADGRA3 adhesion G protein-coupled receptor A3
ADNP activity-dependent neuroprotector homeobox
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANKRD40 ankyrin repeat domain 40
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
BANP BTG3 associated nuclear protein
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C9ORF91 chromosome 9 open reading frame 91
CAPN15 calpain 15
CASD1 CAS1 domain containing 1
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCND1 cyclin D1
CDT1 chromatin licensing and DNA replication factor 1
COA7 cytochrome c oxidase assembly factor 7 (putative)
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DEAF1 DEAF1 transcription factor
DKK1 dickkopf WNT signaling pathway inhibitor 1
EGR3 early growth response 3
EVPL envoplakin
EXOSC10 exosome component 10
FAM57A family with sequence similarity 57, member A
FJX1 four jointed box 1 (Drosophila)
FOXC1 forkhead box C1
GABPB1 GA binding protein transcription factor, beta subunit 1
GATA3 GATA binding protein 3
GPRC5C G protein-coupled receptor, class C, group 5, member C
GRWD1 glutamate-rich WD repeat containing 1
GTF2IRD1 GTF2I repeat domain containing 1
HOXC11 homeobox C11
IL15RA interleukin 15 receptor, alpha
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
IRX5 iroquois homeobox 5
KAT2A K(lysine) acetyltransferase 2A
KAT6B K(lysine) acetyltransferase 6B
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KEAP1 kelch-like ECH-associated protein 1
KIAA0125 KIAA0125
LMNB1 lamin B1
LPAR2 lysophosphatidic acid receptor 2
LY6G5C lymphocyte antigen 6 complex, locus G5C
MCM9 minichromosome maintenance complex component 9
MEPCE methylphosphate capping enzyme
MICALL1 MICAL-like 1
MSL1 male-specific lethal 1 homolog (Drosophila)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NRIP1 nuclear receptor interacting protein 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PCNT pericentrin
PHLDA3 pleckstrin homology-like domain, family A, member 3
PLK1 polo-like kinase 1
POGK pogo transposable element with KRAB domain
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRNP prion protein
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SENP6 SUMO1/sentrin specific peptidase 6
SETD1B SET domain containing 1B
SFMBT1 Scm-like with four mbt domains 1
SLC25A38 solute carrier family 25, member 38
SLC35F2 solute carrier family 35, member F2
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMYD5 SMYD family member 5
SNHG20 small nucleolar RNA host gene 20
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SRSF4 serine/arginine-rich splicing factor 4
STBD1 starch binding domain 1
STC2 stanniocalcin 2
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TMEM223 transmembrane protein 223
TMEM30B transmembrane protein 30B
TNS3 tensin 3
TOE1 target of EGR1, member 1 (nuclear)
TPTE transmembrane phosphatase with tensin homology
TRIB3 tribbles pseudokinase 3
TRIM16 tripartite motif containing 16
TRIM8 tripartite motif containing 8
TSKU tsukushi, small leucine rich proteoglycan
UBXN8 UBX domain protein 8
VRK2 vaccinia related kinase 2
XBP1 X-box binding protein 1
ZBED1 zinc finger, BED-type containing 1
ZBED5 zinc finger, BED-type containing 5
ZIC1 Zic family member 1
ZNF282 zinc finger protein 282
ZNF33B zinc finger protein 33B
ZNF408 zinc finger protein 408
ZNF692 zinc finger protein 692
ZNF787 zinc finger protein 787
ZNHIT2 zinc finger, HIT-type containing 2