trichostatin A-6736 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the trichostatin A-6736 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
AGTR1 angiotensin II receptor, type 1
AKR1C2 aldo-keto reductase family 1, member C2
ANGPTL4 angiopoietin-like 4
APAF1 apoptotic peptidase activating factor 1
AQP3 aquaporin 3 (Gill blood group)
ARG2 arginase 2
ASMTL acetylserotonin O-methyltransferase-like
ATP7A ATPase, Cu++ transporting, alpha polypeptide
BAMBI BMP and activin membrane-bound inhibitor
BMP6 bone morphogenetic protein 6
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFAP69 cilia and flagella associated protein 69
CLDN8 claudin 8
COBL cordon-bleu WH2 repeat protein
COL21A1 collagen, type XXI, alpha 1
COL5A1 collagen, type V, alpha 1
CORO1A coronin, actin binding protein, 1A
CPM carboxypeptidase M
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTGF connective tissue growth factor
CTH cystathionine gamma-lyase
CXCR4 chemokine (C-X-C motif) receptor 4
CYR61 cysteine-rich, angiogenic inducer, 61
DENND3 DENN/MADD domain containing 3
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
EFNA3 ephrin-A3
ENOX1 ecto-NOX disulfide-thiol exchanger 1
EPHA4 EPH receptor A4
EPHB2 EPH receptor B2
FABP4 fatty acid binding protein 4, adipocyte
FAM134B family with sequence similarity 134, member B
FAM69A family with sequence similarity 69, member A
GPRC5A G protein-coupled receptor, class C, group 5, member A
GTF2B general transcription factor IIB
H1FX H1 histone family, member X
HIC2 hypermethylated in cancer 2
HOXA1 homeobox A1
IL11 interleukin 11
IL1RAP interleukin 1 receptor accessory protein
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
INSIG1 insulin induced gene 1
IRF6 interferon regulatory factor 6
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIF5C kinesin family member 5C
LINC00341 long intergenic non-protein coding RNA 341
LIPG lipase, endothelial
LMCD1 LIM and cysteine-rich domains 1
LPPR4 lipid phosphate phosphatase-related protein type 4
MAP2K3 mitogen-activated protein kinase kinase 3
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MAST3 microtubule associated serine/threonine kinase 3
MAX MYC associated factor X
MERTK MER proto-oncogene, tyrosine kinase
MMP1 matrix metallopeptidase 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NME5 NME/NM23 family member 5
NPC1 Niemann-Pick disease, type C1
NR4A2 nuclear receptor subfamily 4, group A, member 2
OASL 2'-5'-oligoadenylate synthetase-like
PCDH9 protocadherin 9
PDE4DIP phosphodiesterase 4D interacting protein
PLK2 polo-like kinase 2
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB31 RAB31, member RAS oncogene family
RAI2 retinoic acid induced 2
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS17 regulator of G-protein signaling 17
RGS4 regulator of G-protein signaling 4
RHOB ras homolog family member B
RUNX1 runt-related transcription factor 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SORBS1 sorbin and SH3 domain containing 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STC1 stanniocalcin 1
STOM stomatin
SYT1 synaptotagmin I
SYT11 synaptotagmin XI
TBC1D2 TBC1 domain family, member 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TNIK TRAF2 and NCK interacting kinase
TUBB2B tubulin, beta 2B class IIb
TUFT1 tuftelin 1
UGCG UDP-glucose ceramide glucosyltransferase
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
ADNP activity-dependent neuroprotector homeobox
AFAP1 actin filament associated protein 1
AKAP8 A kinase (PRKA) anchor protein 8
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARSJ arylsulfatase family, member J
ATF1 activating transcription factor 1
BCAR3 breast cancer anti-estrogen resistance 3
C19ORF54 chromosome 19 open reading frame 54
CASD1 CAS1 domain containing 1
CBR3 carbonyl reductase 3
CCDC101 coiled-coil domain containing 101
CCDC59 coiled-coil domain containing 59
CDC7 cell division cycle 7
CPEB1 cytoplasmic polyadenylation element binding protein 1
CTCF CCCTC-binding factor (zinc finger protein)
CUL1 cullin 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DEPDC1 DEP domain containing 1
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
E2F8 E2F transcription factor 8
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
ERF Ets2 repressor factor
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ETV4 ets variant 4
FJX1 four jointed box 1 (Drosophila)
FOXA1 forkhead box A1
FST follistatin
GABPB1 GA binding protein transcription factor, beta subunit 1
GBX2 gastrulation brain homeobox 2
GTF2I general transcription factor IIi
HAS2 hyaluronan synthase 2
HMGA2 high mobility group AT-hook 2
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IL7R interleukin 7 receptor
INHBB inhibin, beta B
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
KAT6B K(lysine) acetyltransferase 6B
KEAP1 kelch-like ECH-associated protein 1
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LIF leukemia inhibitory factor
LMNB1 lamin B1
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRRC41 leucine rich repeat containing 41
LUC7L2 LUC7-like 2 (S. cerevisiae)
LY6G5C lymphocyte antigen 6 complex, locus G5C
MEPCE methylphosphate capping enzyme
MLPH melanophilin
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MSL1 male-specific lethal 1 homolog (Drosophila)
NLRX1 NLR family member X1
NMI N-myc (and STAT) interactor
NPY1R neuropeptide Y receptor Y1
NRIP1 nuclear receptor interacting protein 1
NUPR1 nuclear protein, transcriptional regulator, 1
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PALMD palmdelphin
PCNT pericentrin
PLAU plasminogen activator, urokinase
PLK1 polo-like kinase 1
PPAP2B phosphatidic acid phosphatase type 2B
PRMT7 protein arginine methyltransferase 7
PTK6 protein tyrosine kinase 6
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RIN2 Ras and Rab interactor 2
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SETD1B SET domain containing 1B
SFMBT1 Scm-like with four mbt domains 1
SLC12A8 solute carrier family 12, member 8
SMAGP small cell adhesion glycoprotein
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMG9 SMG9 nonsense mediated mRNA decay factor
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SMYD5 SMYD family member 5
SRSF4 serine/arginine-rich splicing factor 4
STBD1 starch binding domain 1
SUN2 Sad1 and UNC84 domain containing 2
SYNPO synaptopodin
TACO1 translational activator of mitochondrially encoded cytochrome c oxidase I
TARBP2 TAR (HIV-1) RNA binding protein 2
TENM4 teneurin transmembrane protein 4
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TOE1 target of EGR1, member 1 (nuclear)
TRIB3 tribbles pseudokinase 3
TTC27 tetratricopeptide repeat domain 27
TUBGCP3 tubulin, gamma complex associated protein 3
UBXN8 UBX domain protein 8
VEGFC vascular endothelial growth factor C
VWA9 von Willebrand factor A domain containing 9
WBSCR16 Williams-Beuren syndrome chromosome region 16
WDR33 WD repeat domain 33
WDR6 WD repeat domain 6
ZBED1 zinc finger, BED-type containing 1
ZC3H4 zinc finger CCCH-type containing 4
ZFP69B ZFP69 zinc finger protein B
ZNF165 zinc finger protein 165
ZNF668 zinc finger protein 668
ZNF675 zinc finger protein 675
ZNF804A zinc finger protein 804A
ZSCAN31 zinc finger and SCAN domain containing 31