trichostatin A-6671 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the trichostatin A-6671 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABAT 4-aminobutyrate aminotransferase
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ADGRB2 adhesion G protein-coupled receptor B2
AGTR1 angiotensin II receptor, type 1
AIM1L absent in melanoma 1-like
APAF1 apoptotic peptidase activating factor 1
AQP3 aquaporin 3 (Gill blood group)
ARG2 arginase 2
BMP4 bone morphogenetic protein 4
C1ORF116 chromosome 1 open reading frame 116
CA12 carbonic anhydrase XII
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEND1 cell cycle exit and neuronal differentiation 1
CHN2 chimerin 2
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CLTCL1 clathrin, heavy chain-like 1
CNTNAP2 contactin associated protein-like 2
COBL cordon-bleu WH2 repeat protein
CORO1A coronin, actin binding protein, 1A
CPM carboxypeptidase M
CREB5 cAMP responsive element binding protein 5
CTH cystathionine gamma-lyase
CXCR4 chemokine (C-X-C motif) receptor 4
CYR61 cysteine-rich, angiogenic inducer, 61
CYTH3 cytohesin 3
DENND3 DENN/MADD domain containing 3
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DUSP5 dual specificity phosphatase 5
EDN1 endothelin 1
EFHC2 EF-hand domain (C-terminal) containing 2
EFNA3 ephrin-A3
EGR2 early growth response 2
ENOX1 ecto-NOX disulfide-thiol exchanger 1
ETV1 ets variant 1
FABP4 fatty acid binding protein 4, adipocyte
FAM134B family with sequence similarity 134, member B
FAM69A family with sequence similarity 69, member A
FYN FYN proto-oncogene, Src family tyrosine kinase
GIPR gastric inhibitory polypeptide receptor
GOLGA8A golgin A8 family, member A
GPRC5B G protein-coupled receptor, class C, group 5, member B
GSN gelsolin
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HAP1 huntingtin-associated protein 1
HOXA1 homeobox A1
IL1RAP interleukin 1 receptor accessory protein
IL1RN interleukin 1 receptor antagonist
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIF5C kinesin family member 5C
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KMT2A lysine (K)-specific methyltransferase 2A
LIFR leukemia inhibitory factor receptor alpha
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
LPPR4 lipid phosphate phosphatase-related protein type 4
LYST lysosomal trafficking regulator
MAP2 microtubule-associated protein 2
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MERTK MER proto-oncogene, tyrosine kinase
MTCP1 mature T-cell proliferation 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NR4A2 nuclear receptor subfamily 4, group A, member 2
PCDH17 protocadherin 17
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PELI2 pellino E3 ubiquitin protein ligase family member 2
PGLYRP1 peptidoglycan recognition protein 1
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PKP2 plakophilin 2
PRPH peripherin
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
RAI2 retinoic acid induced 2
RGCC regulator of cell cycle
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS4 regulator of G-protein signaling 4
RND1 Rho family GTPase 1
RRAGD Ras-related GTP binding D
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SIRT4 sirtuin 4
SIT1 signaling threshold regulating transmembrane adaptor 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SOSTDC1 sclerostin domain containing 1
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
SSBP2 single-stranded DNA binding protein 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAT4 signal transducer and activator of transcription 4
STC1 stanniocalcin 1
SYT1 synaptotagmin I
TAGLN3 transgelin 3
TMEM47 transmembrane protein 47
TNIK TRAF2 and NCK interacting kinase
TUBB2B tubulin, beta 2B class IIb
TUFT1 tuftelin 1
USP2 ubiquitin specific peptidase 2
VWA5A von Willebrand factor A domain containing 5A

decreased expression

Symbol Name
ADNP activity-dependent neuroprotector homeobox
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALPK1 alpha-kinase 1
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARSJ arylsulfatase family, member J
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BCAR3 breast cancer anti-estrogen resistance 3
C9ORF91 chromosome 9 open reading frame 91
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CASD1 CAS1 domain containing 1
CBR3 carbonyl reductase 3
CCDC94 coiled-coil domain containing 94
CHKB choline kinase beta
CLCF1 cardiotrophin-like cytokine factor 1
CTCF CCCTC-binding factor (zinc finger protein)
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CUL1 cullin 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DENND4B DENN/MADD domain containing 4B
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EXOSC10 exosome component 10
FAIM Fas apoptotic inhibitory molecule
FAM57A family with sequence similarity 57, member A
FJX1 four jointed box 1 (Drosophila)
FST follistatin
GABPB1 GA binding protein transcription factor, beta subunit 1
GLS2 glutaminase 2 (liver, mitochondrial)
GMEB1 glucocorticoid modulatory element binding protein 1
GNA14 guanine nucleotide binding protein (G protein), alpha 14
HAS2 hyaluronan synthase 2
HIRIP3 HIRA interacting protein 3
HMGA2 high mobility group AT-hook 2
INHBB inhibin, beta B
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
KAT6B K(lysine) acetyltransferase 6B
KAT7 K(lysine) acetyltransferase 7
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCTD7 potassium channel tetramerization domain containing 7
KEAP1 kelch-like ECH-associated protein 1
KLF11 Kruppel-like factor 11
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LIF leukemia inhibitory factor
LMNB1 lamin B1
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LUC7L2 LUC7-like 2 (S. cerevisiae)
LY6G5C lymphocyte antigen 6 complex, locus G5C
LYRM9 LYR motif containing 9
MAGEF1 melanoma antigen family F1
MAP3K6 mitogen-activated protein kinase kinase kinase 6
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MEPCE methylphosphate capping enzyme
MISP mitotic spindle positioning
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MYL5 myosin, light chain 5, regulatory
NARFL nuclear prelamin A recognition factor-like
NMI N-myc (and STAT) interactor
NSD1 nuclear receptor binding SET domain protein 1
OVGP1 oviductal glycoprotein 1, 120kDa
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PCNT pericentrin
PHF11 PHD finger protein 11
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RABL3 RAB, member of RAS oncogene family-like 3
RIN2 Ras and Rab interactor 2
SCAF8 SR-related CTD-associated factor 8
SCO2 SCO2 cytochrome c oxidase assembly protein
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SETD1B SET domain containing 1B
SH2D4A SH2 domain containing 4A
SLC12A8 solute carrier family 12, member 8
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMAGP small cell adhesion glycoprotein
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNUPN snurportin 1
SRSF4 serine/arginine-rich splicing factor 4
STAG1 stromal antigen 1
STXBP3 syntaxin binding protein 3
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TARBP2 TAR (HIV-1) RNA binding protein 2
TENM4 teneurin transmembrane protein 4
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TMEM53 transmembrane protein 53
TOR4A torsin family 4, member A
TRIB3 tribbles pseudokinase 3
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
UBTF upstream binding transcription factor, RNA polymerase I
UNKL unkempt family zinc finger-like
USP21 ubiquitin specific peptidase 21
VEGFC vascular endothelial growth factor C
WDR6 WD repeat domain 6
WDR74 WD repeat domain 74
ZBED1 zinc finger, BED-type containing 1
ZBTB3 zinc finger and BTB domain containing 3
ZNF804A zinc finger protein 804A
ZZZ3 zinc finger, ZZ-type containing 3