trichostatin A-6609 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the trichostatin A-6609 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AADAC arylacetamide deacetylase
ABAT 4-aminobutyrate aminotransferase
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
AGTR1 angiotensin II receptor, type 1
AQP3 aquaporin 3 (Gill blood group)
ARG2 arginase 2
ARHGAP6 Rho GTPase activating protein 6
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASMTL acetylserotonin O-methyltransferase-like
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
AVPI1 arginine vasopressin-induced 1
BAMBI BMP and activin membrane-bound inhibitor
BIRC3 baculoviral IAP repeat containing 3
BMP4 bone morphogenetic protein 4
C1ORF116 chromosome 1 open reading frame 116
CCDC68 coiled-coil domain containing 68
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
COBL cordon-bleu WH2 repeat protein
CORO1A coronin, actin binding protein, 1A
CPA4 carboxypeptidase A4
CPM carboxypeptidase M
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTGF connective tissue growth factor
CTH cystathionine gamma-lyase
CYR61 cysteine-rich, angiogenic inducer, 61
DENND3 DENN/MADD domain containing 3
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLC1 DLC1 Rho GTPase activating protein
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DOPEY1 dopey family member 1
DPF3 D4, zinc and double PHD fingers, family 3
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
DUSP5 dual specificity phosphatase 5
EFNA3 ephrin-A3
EIF5A2 eukaryotic translation initiation factor 5A2
ELOVL4 ELOVL fatty acid elongase 4
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPHB2 EPH receptor B2
FABP4 fatty acid binding protein 4, adipocyte
FAM69A family with sequence similarity 69, member A
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GLRX glutaredoxin (thioltransferase)
GLS glutaminase
GMPR guanosine monophosphate reductase
GSN gelsolin
HBEGF heparin-binding EGF-like growth factor
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOXA1 homeobox A1
IL1RAP interleukin 1 receptor accessory protein
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIF5C kinesin family member 5C
KITLG KIT ligand
LIMA1 LIM domain and actin binding 1
LMCD1 LIM and cysteine-rich domains 1
LPPR4 lipid phosphate phosphatase-related protein type 4
LYST lysosomal trafficking regulator
MAP2K3 mitogen-activated protein kinase kinase 3
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MERTK MER proto-oncogene, tyrosine kinase
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRXN3 neurexin 3
PAQR5 progestin and adipoQ receptor family member V
PDE4DIP phosphodiesterase 4D interacting protein
PID1 phosphotyrosine interaction domain containing 1
PKP2 plakophilin 2
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRPH peripherin
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RGCC regulator of cell cycle
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS4 regulator of G-protein signaling 4
RGS7 regulator of G-protein signaling 7
RND1 Rho family GTPase 1
RUNDC3B RUN domain containing 3B
SEPP1 selenoprotein P, plasma, 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SORBS1 sorbin and SH3 domain containing 1
SOSTDC1 sclerostin domain containing 1
SQLE squalene epoxidase
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
STC1 stanniocalcin 1
STK17B serine/threonine kinase 17b
STOM stomatin
SYT1 synaptotagmin I
TAOK3 TAO kinase 3
TJP3 tight junction protein 3
TRAFD1 TRAF-type zinc finger domain containing 1
TUBB2B tubulin, beta 2B class IIb
TUFT1 tuftelin 1

decreased expression

Symbol Name
ADNP activity-dependent neuroprotector homeobox
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARSJ arylsulfatase family, member J
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BCAR3 breast cancer anti-estrogen resistance 3
BOLA1 bolA family member 1
C19ORF54 chromosome 19 open reading frame 54
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CBR3 carbonyl reductase 3
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CLCF1 cardiotrophin-like cytokine factor 1
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CUL1 cullin 1
CYTH2 cytohesin 2
DEPDC1 DEP domain containing 1
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EXOSC10 exosome component 10
FAM57A family with sequence similarity 57, member A
FJX1 four jointed box 1 (Drosophila)
FOXA1 forkhead box A1
FST follistatin
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
H2AFY2 H2A histone family, member Y2
HAS2 hyaluronan synthase 2
HEATR3 HEAT repeat containing 3
HMBOX1 homeobox containing 1
HMGA2 high mobility group AT-hook 2
HMGXB4 HMG box domain containing 4
INHBB inhibin, beta B
IRF9 interferon regulatory factor 9
KAT6B K(lysine) acetyltransferase 6B
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KEAP1 kelch-like ECH-associated protein 1
LIF leukemia inhibitory factor
LMNB1 lamin B1
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRRC41 leucine rich repeat containing 41
LUC7L2 LUC7-like 2 (S. cerevisiae)
MED24 mediator complex subunit 24
MEPCE methylphosphate capping enzyme
NDP Norrie disease (pseudoglioma)
NHEJ1 nonhomologous end-joining factor 1
NME6 NME/NM23 nucleoside diphosphate kinase 6
NMI N-myc (and STAT) interactor
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
PALMD palmdelphin
PARP16 poly (ADP-ribose) polymerase family, member 16
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLK1 polo-like kinase 1
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PPAN peter pan homolog (Drosophila)
PPAP2B phosphatidic acid phosphatase type 2B
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PTK6 protein tyrosine kinase 6
RAD54L2 RAD54-like 2 (S. cerevisiae)
RBL1 retinoblastoma-like 1
RBM39 RNA binding motif protein 39
RBM4B RNA binding motif protein 4B
RIN2 Ras and Rab interactor 2
SCAF8 SR-related CTD-associated factor 8
SCO2 SCO2 cytochrome c oxidase assembly protein
SETMAR SET domain and mariner transposase fusion gene
SFMBT1 Scm-like with four mbt domains 1
SH2D4A SH2 domain containing 4A
SIAH1 siah E3 ubiquitin protein ligase 1
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SMAGP small cell adhesion glycoprotein
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMG9 SMG9 nonsense mediated mRNA decay factor
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SNHG3 small nucleolar RNA host gene 3
SPHK1 sphingosine kinase 1
SRSF4 serine/arginine-rich splicing factor 4
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TACO1 translational activator of mitochondrially encoded cytochrome c oxidase I
TARBP2 TAR (HIV-1) RNA binding protein 2
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TOE1 target of EGR1, member 1 (nuclear)
TRIB3 tribbles pseudokinase 3
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
UBTF upstream binding transcription factor, RNA polymerase I
UNKL unkempt family zinc finger-like
VEGFC vascular endothelial growth factor C
VWA9 von Willebrand factor A domain containing 9
WBSCR16 Williams-Beuren syndrome chromosome region 16
WDR18 WD repeat domain 18
ZBED1 zinc finger, BED-type containing 1
ZBTB38 zinc finger and BTB domain containing 38
ZC3H4 zinc finger CCCH-type containing 4
ZC3H7A zinc finger CCCH-type containing 7A
ZFP69B ZFP69 zinc finger protein B
ZNF16 zinc finger protein 16
ZNF562 zinc finger protein 562
ZNF804A zinc finger protein 804A