trichostatin A-6551 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the trichostatin A-6551 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
AGFG2 ArfGAP with FG repeats 2
AHNAK2 AHNAK nucleoprotein 2
ARMCX2 armadillo repeat containing, X-linked 2
BAIAP3 BAI1-associated protein 3
BEX4 brain expressed, X-linked 4
CASC1 cancer susceptibility candidate 1
CCDC28A coiled-coil domain containing 28A
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDH18 cadherin 18, type 2
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CLGN calmegin
CLMN calmin (calponin-like, transmembrane)
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSRP2 cysteine and glycine-rich protein 2
CXADR coxsackie virus and adenovirus receptor
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DEGS1 delta(4)-desaturase, sphingolipid 1
DENND3 DENN/MADD domain containing 3
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DPYSL4 dihydropyrimidinase-like 4
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFNA3 ephrin-A3
EPOR erythropoietin receptor
FADS3 fatty acid desaturase 3
FAM46C family with sequence similarity 46, member C
FKBP1B FK506 binding protein 1B, 12.6 kDa
FN1 fibronectin 1
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GEM GTP binding protein overexpressed in skeletal muscle
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GLCE glucuronic acid epimerase
GLDC glycine dehydrogenase (decarboxylating)
GLRX glutaredoxin (thioltransferase)
GRAMD1C GRAM domain containing 1C
GRK5 G protein-coupled receptor kinase 5
GTF2B general transcription factor IIB
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HSPA2 heat shock 70kDa protein 2
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGFBP3 insulin-like growth factor binding protein 3
IRF7 interferon regulatory factor 7
JAG1 jagged 1
KIAA0895 KIAA0895
KIF21B kinesin family member 21B
KIF5C kinesin family member 5C
KIFAP3 kinesin-associated protein 3
KLF5 Kruppel-like factor 5 (intestinal)
LIMA1 LIM domain and actin binding 1
LYST lysosomal trafficking regulator
MAP1A microtubule-associated protein 1A
MAP1B microtubule-associated protein 1B
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MLF1 myeloid leukemia factor 1
NPC1 Niemann-Pick disease, type C1
PADI3 peptidyl arginine deiminase, type III
PARP16 poly (ADP-ribose) polymerase family, member 16
PCDH9 protocadherin 9
PDE4DIP phosphodiesterase 4D interacting protein
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PMEL premelanosome protein
PRPH peripherin
RAI2 retinoic acid induced 2
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
RPL3L ribosomal protein L3-like
RUNDC3B RUN domain containing 3B
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPP1 selenoprotein P, plasma, 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SIRT4 sirtuin 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STK17A serine/threonine kinase 17a
STON1 stonin 1
STX12 syntaxin 12
SYT11 synaptotagmin XI
TBC1D2 TBC1 domain family, member 2
TBXA2R thromboxane A2 receptor
TMSB15A thymosin beta 15a
TUFT1 tuftelin 1
WDR19 WD repeat domain 19
WDR47 WD repeat domain 47
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZCCHC24 zinc finger, CCHC domain containing 24
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF10 zinc finger protein 10
ZNF204P zinc finger protein 204, pseudogene

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADNP activity-dependent neuroprotector homeobox
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ATAD2B ATPase family, AAA domain containing 2B
BANP BTG3 associated nuclear protein
BATF basic leucine zipper transcription factor, ATF-like
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C19ORF40 chromosome 19 open reading frame 40
C9ORF40 chromosome 9 open reading frame 40
C9ORF91 chromosome 9 open reading frame 91
CALHM2 calcium homeostasis modulator 2
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCND1 cyclin D1
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
COA7 cytochrome c oxidase assembly factor 7 (putative)
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
EFNA1 ephrin-A1
EGR3 early growth response 3
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ESRP2 epithelial splicing regulatory protein 2
FAIM Fas apoptotic inhibitory molecule
FAM57A family with sequence similarity 57, member A
FBRS fibrosin
FJX1 four jointed box 1 (Drosophila)
FKBP10 FK506 binding protein 10, 65 kDa
FOXA1 forkhead box A1
FOXC1 forkhead box C1
FOXD1 forkhead box D1
GABPB1 GA binding protein transcription factor, beta subunit 1
GATA3 GATA binding protein 3
GMEB1 glucocorticoid modulatory element binding protein 1
GTF2IRD1 GTF2I repeat domain containing 1
H2AFY2 H2A histone family, member Y2
HP1BP3 heterochromatin protein 1, binding protein 3
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
IRX5 iroquois homeobox 5
ITPKB inositol-trisphosphate 3-kinase B
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KEAP1 kelch-like ECH-associated protein 1
LMNB1 lamin B1
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
MCM9 minichromosome maintenance complex component 9
MEPCE methylphosphate capping enzyme
MSL1 male-specific lethal 1 homolog (Drosophila)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NPY5R neuropeptide Y receptor Y5
NRIP1 nuclear receptor interacting protein 1
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
NUAK1 NUAK family, SNF1-like kinase, 1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PHLDA3 pleckstrin homology-like domain, family A, member 3
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLK1 polo-like kinase 1
POGK pogo transposable element with KRAB domain
PPAN peter pan homolog (Drosophila)
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRR15L proline rich 15-like
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SETD1B SET domain containing 1B
SFMBT1 Scm-like with four mbt domains 1
SH2D4A SH2 domain containing 4A
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMAD7 SMAD family member 7
SMG9 SMG9 nonsense mediated mRNA decay factor
SNHG3 small nucleolar RNA host gene 3
STC2 stanniocalcin 2
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TMEM30B transmembrane protein 30B
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TOE1 target of EGR1, member 1 (nuclear)
TRIB3 tribbles pseudokinase 3
TRIM16 tripartite motif containing 16
TRIM8 tripartite motif containing 8
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSKU tsukushi, small leucine rich proteoglycan
TSSC4 tumor suppressing subtransferable candidate 4
UBL4A ubiquitin-like 4A
UBTF upstream binding transcription factor, RNA polymerase I
UBXN8 UBX domain protein 8
URGCP upregulator of cell proliferation
XBP1 X-box binding protein 1
ZBED1 zinc finger, BED-type containing 1
ZC3H4 zinc finger CCCH-type containing 4
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF573 zinc finger protein 573
ZNF668 zinc finger protein 668
ZNF692 zinc finger protein 692
ZNF787 zinc finger protein 787
ZNHIT2 zinc finger, HIT-type containing 2