trichostatin A-6493 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the trichostatin A-6493 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADD3 adducin 3 (gamma)
ADM adrenomedullin
AGFG2 ArfGAP with FG repeats 2
AHNAK2 AHNAK nucleoprotein 2
ANGPTL4 angiopoietin-like 4
ARMCX2 armadillo repeat containing, X-linked 2
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
BAIAP3 BAI1-associated protein 3
C19ORF66 chromosome 19 open reading frame 66
CA5B carbonic anhydrase VB, mitochondrial
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEP112 centrosomal protein 112kDa
CLGN calmegin
CORO1A coronin, actin binding protein, 1A
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CXADR coxsackie virus and adenovirus receptor
CXCR4 chemokine (C-X-C motif) receptor 4
CYLD cylindromatosis (turban tumor syndrome)
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DPYSL4 dihydropyrimidinase-like 4
EFNA3 ephrin-A3
EFNB3 ephrin-B3
EPOR erythropoietin receptor
FAM105A family with sequence similarity 105, member A
FAM13A family with sequence similarity 13, member A
FAM46C family with sequence similarity 46, member C
FKBP1B FK506 binding protein 1B, 12.6 kDa
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GEM GTP binding protein overexpressed in skeletal muscle
GLDC glycine dehydrogenase (decarboxylating)
GLRX glutaredoxin (thioltransferase)
GRK5 G protein-coupled receptor kinase 5
GTF2B general transcription factor IIB
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HOXA1 homeobox A1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
INSIG1 insulin induced gene 1
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KIAA0513 KIAA0513
KIF21B kinesin family member 21B
KIF5C kinesin family member 5C
LIMA1 LIM domain and actin binding 1
LINC00341 long intergenic non-protein coding RNA 341
LMCD1 LIM and cysteine-rich domains 1
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MMD monocyte to macrophage differentiation-associated
NME5 NME/NM23 family member 5
NPC1 Niemann-Pick disease, type C1
NRTN neurturin
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
NXN nucleoredoxin
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PKNOX2 PBX/knotted 1 homeobox 2
PMEL premelanosome protein
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
PRPH peripherin
PTRF polymerase I and transcript release factor
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAI2 retinoic acid induced 2
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RGCC regulator of cell cycle
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
RND1 Rho family GTPase 1
RPL3L ribosomal protein L3-like
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RUNDC3B RUN domain containing 3B
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPP1 selenoprotein P, plasma, 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SIPA1 signal-induced proliferation-associated 1
SIRT4 sirtuin 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SORBS1 sorbin and SH3 domain containing 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STXBP1 syntaxin binding protein 1
SYT11 synaptotagmin XI
TBXA2R thromboxane A2 receptor
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRIM2 tripartite motif containing 2
TUBA4A tubulin, alpha 4a
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
WDR47 WD repeat domain 47
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF204P zinc finger protein 204, pseudogene
ZNF778 zinc finger protein 778

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADGRA3 adhesion G protein-coupled receptor A3
ADNP activity-dependent neuroprotector homeobox
ADRA2C adrenoceptor alpha 2C
AES amino-terminal enhancer of split
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
BANP BTG3 associated nuclear protein
BCAR3 breast cancer anti-estrogen resistance 3
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C7ORF49 chromosome 7 open reading frame 49
CALHM2 calcium homeostasis modulator 2
CAMKMT calmodulin-lysine N-methyltransferase
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCND1 cyclin D1
CDT1 chromatin licensing and DNA replication factor 1
COA7 cytochrome c oxidase assembly factor 7 (putative)
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DKK1 dickkopf WNT signaling pathway inhibitor 1
DTWD1 DTW domain containing 1
EFNA1 ephrin-A1
EGR3 early growth response 3
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
ESRP2 epithelial splicing regulatory protein 2
FAIM Fas apoptotic inhibitory molecule
FAM57A family with sequence similarity 57, member A
FJX1 four jointed box 1 (Drosophila)
FOXA1 forkhead box A1
GABPB1 GA binding protein transcription factor, beta subunit 1
GATA3 GATA binding protein 3
GLI3 GLI family zinc finger 3
GTF2I general transcription factor IIi
HMGXB4 HMG box domain containing 4
HOXC11 homeobox C11
IL15RA interleukin 15 receptor, alpha
INHBB inhibin, beta B
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
INPPL1 inositol polyphosphate phosphatase-like 1
IRS1 insulin receptor substrate 1
IRX5 iroquois homeobox 5
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KEAP1 kelch-like ECH-associated protein 1
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
LUC7L2 LUC7-like 2 (S. cerevisiae)
LY6G5C lymphocyte antigen 6 complex, locus G5C
MCM9 minichromosome maintenance complex component 9
MEPCE methylphosphate capping enzyme
METTL8 methyltransferase like 8
MICALL1 MICAL-like 1
MPPED2 metallophosphoesterase domain containing 2
MSL1 male-specific lethal 1 homolog (Drosophila)
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
NHEJ1 nonhomologous end-joining factor 1
NPY1R neuropeptide Y receptor Y1
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRIP1 nuclear receptor interacting protein 1
NSD1 nuclear receptor binding SET domain protein 1
NUAK1 NUAK family, SNF1-like kinase, 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PCNT pericentrin
POGK pogo transposable element with KRAB domain
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM15B RNA binding motif protein 15B
RCOR3 REST corepressor 3
SENP6 SUMO1/sentrin specific peptidase 6
SFMBT1 Scm-like with four mbt domains 1
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMG9 SMG9 nonsense mediated mRNA decay factor
SMYD5 SMYD family member 5
SPHK1 sphingosine kinase 1
SREK1 splicing regulatory glutamine/lysine-rich protein 1
STC2 stanniocalcin 2
TGIF1 TGFB-induced factor homeobox 1
TOE1 target of EGR1, member 1 (nuclear)
TRIB3 tribbles pseudokinase 3
TRIM16 tripartite motif containing 16
TRIM8 tripartite motif containing 8
TRPS1 trichorhinophalangeal syndrome I
TSKU tsukushi, small leucine rich proteoglycan
TSSC4 tumor suppressing subtransferable candidate 4
UBXN8 UBX domain protein 8
URGCP upregulator of cell proliferation
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
WDR74 WD repeat domain 74
XBP1 X-box binding protein 1
YAP1 Yes-associated protein 1
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1
ZNF282 zinc finger protein 282
ZNF692 zinc finger protein 692