trichostatin A-6454 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the trichostatin A-6454 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADM adrenomedullin
AHNAK2 AHNAK nucleoprotein 2
AKAP12 A kinase (PRKA) anchor protein 12
ARMCX2 armadillo repeat containing, X-linked 2
ARNT aryl hydrocarbon receptor nuclear translocator
CA5B carbonic anhydrase VB, mitochondrial
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEP112 centrosomal protein 112kDa
CLGN calmegin
CORO1A coronin, actin binding protein, 1A
CXADR coxsackie virus and adenovirus receptor
CXCR4 chemokine (C-X-C motif) receptor 4
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DFNB31 deafness, autosomal recessive 31
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLX2 distal-less homeobox 2
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DPYSL4 dihydropyrimidinase-like 4
EFNA3 ephrin-A3
EFNB3 ephrin-B3
ELOVL4 ELOVL fatty acid elongase 4
EPOR erythropoietin receptor
FAM46C family with sequence similarity 46, member C
FKBP1B FK506 binding protein 1B, 12.6 kDa
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GCHFR GTP cyclohydrolase I feedback regulator
GEM GTP binding protein overexpressed in skeletal muscle
GLDC glycine dehydrogenase (decarboxylating)
GLRX glutaredoxin (thioltransferase)
GRK5 G protein-coupled receptor kinase 5
H1F0 H1 histone family, member 0
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HIC2 hypermethylated in cancer 2
HOXA1 homeobox A1
HYAL1 hyaluronoglucosaminidase 1
IFI6 interferon, alpha-inducible protein 6
ITM2C integral membrane protein 2C
KIF5C kinesin family member 5C
LIMA1 LIM domain and actin binding 1
LINC00341 long intergenic non-protein coding RNA 341
LMBR1L limb development membrane protein 1-like
LYST lysosomal trafficking regulator
MANBA mannosidase, beta A, lysosomal
MAP1A microtubule-associated protein 1A
MAP1B microtubule-associated protein 1B
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MAST3 microtubule associated serine/threonine kinase 3
MMD monocyte to macrophage differentiation-associated
MUC3B mucin 3B, cell surface associated
NDRG4 NDRG family member 4
NME5 NME/NM23 family member 5
NXN nucleoredoxin
OPTN optineurin
PADI3 peptidyl arginine deiminase, type III
PCDH1 protocadherin 1
PDE4DIP phosphodiesterase 4D interacting protein
PLK3 polo-like kinase 3
PRPH peripherin
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTCH1 patched 1
RAI2 retinoic acid induced 2
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RNASE4 ribonuclease, RNase A family, 4
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RRAGD Ras-related GTP binding D
RUNDC3B RUN domain containing 3B
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPP1 selenoprotein P, plasma, 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SFXN3 sideroflexin 3
SH3GL3 SH3-domain GRB2-like 3
SIRT4 sirtuin 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SOAT1 sterol O-acyltransferase 1
SORBS1 sorbin and SH3 domain containing 1
SPEG SPEG complex locus
STON1 stonin 1
STX2 syntaxin 2
STXBP1 syntaxin binding protein 1
SYT11 synaptotagmin XI
TBXA2R thromboxane A2 receptor
TNS1 tensin 1
TUBA4A tubulin, alpha 4a
TXNIP thioredoxin interacting protein
ULBP2 UL16 binding protein 2
WSCD1 WSC domain containing 1
ZCCHC24 zinc finger, CCHC domain containing 24
ZDHHC11 zinc finger, DHHC-type containing 11
ZER1 zyg-11 related, cell cycle regulator
ZNF204P zinc finger protein 204, pseudogene
ZNF230 zinc finger protein 230

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ACKR3 atypical chemokine receptor 3
ADCY7 adenylate cyclase 7
ADNP activity-dependent neuroprotector homeobox
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
BATF basic leucine zipper transcription factor, ATF-like
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C1ORF159 chromosome 1 open reading frame 159
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCND1 cyclin D1
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3
CHRM3 cholinergic receptor, muscarinic 3
CNGB3 cyclic nucleotide gated channel beta 3
CTPS1 CTP synthase 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ESRP2 epithelial splicing regulatory protein 2
FAM57A family with sequence similarity 57, member A
FAM63A family with sequence similarity 63, member A
FJX1 four jointed box 1 (Drosophila)
GABPB1 GA binding protein transcription factor, beta subunit 1
GTF2IRD1 GTF2I repeat domain containing 1
HIRIP3 HIRA interacting protein 3
IL15RA interleukin 15 receptor, alpha
INHBB inhibin, beta B
IPP intracisternal A particle-promoted polypeptide
IRS1 insulin receptor substrate 1
IRX4 iroquois homeobox 4
IRX5 iroquois homeobox 5
ITPKB inositol-trisphosphate 3-kinase B
KAT2A K(lysine) acetyltransferase 2A
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCTD15 potassium channel tetramerization domain containing 15
KDM8 lysine (K)-specific demethylase 8
KEAP1 kelch-like ECH-associated protein 1
LMNB1 lamin B1
LRRC61 leucine rich repeat containing 61
LUC7L2 LUC7-like 2 (S. cerevisiae)
LY6G5C lymphocyte antigen 6 complex, locus G5C
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MCM9 minichromosome maintenance complex component 9
MEPCE methylphosphate capping enzyme
METTL1 methyltransferase like 1
METTL8 methyltransferase like 8
MSL1 male-specific lethal 1 homolog (Drosophila)
NR1H2 nuclear receptor subfamily 1, group H, member 2
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
NUAK1 NUAK family, SNF1-like kinase, 1
PACS1 phosphofurin acidic cluster sorting protein 1
PCNT pericentrin
PGP phosphoglycolate phosphatase
PHC1 polyhomeotic homolog 1 (Drosophila)
PISD phosphatidylserine decarboxylase
POGK pogo transposable element with KRAB domain
POLR3B polymerase (RNA) III (DNA directed) polypeptide B
PPAN peter pan homolog (Drosophila)
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRR7 proline rich 7 (synaptic)
PTDSS2 phosphatidylserine synthase 2
PUS1 pseudouridylate synthase 1
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
SCRN1 secernin 1
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SH2D4A SH2 domain containing 4A
SLC12A8 solute carrier family 12, member 8
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMG5 SMG5 nonsense mediated mRNA decay factor
SMYD5 SMYD family member 5
SPAG7 sperm associated antigen 7
SREK1 splicing regulatory glutamine/lysine-rich protein 1
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STC2 stanniocalcin 2
TARP TCR gamma alternate reading frame protein
TCTN1 tectonic family member 1
TMEM62 transmembrane protein 62
TRIB3 tribbles pseudokinase 3
TRIM8 tripartite motif containing 8
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TSKU tsukushi, small leucine rich proteoglycan
UBE2Z ubiquitin-conjugating enzyme E2Z
UBTF upstream binding transcription factor, RNA polymerase I
UBXN8 UBX domain protein 8
URGCP upregulator of cell proliferation
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
XBP1 X-box binding protein 1
ZBED1 zinc finger, BED-type containing 1
ZFHX3 zinc finger homeobox 3
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1
ZNF692 zinc finger protein 692
ZNF768 zinc finger protein 768
ZNHIT2 zinc finger, HIT-type containing 2