trichostatin A-6439 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the trichostatin A-6439 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ADRB2 adrenoceptor beta 2, surface
ANGPTL4 angiopoietin-like 4
APP amyloid beta (A4) precursor protein
AQP3 aquaporin 3 (Gill blood group)
ARG2 arginase 2
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASMTL acetylserotonin O-methyltransferase-like
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
BAIAP2 BAI1-associated protein 2
BAMBI BMP and activin membrane-bound inhibitor
BMP6 bone morphogenetic protein 6
C18ORF8 chromosome 18 open reading frame 8
CCND3 cyclin D3
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFAP69 cilia and flagella associated protein 69
CPM carboxypeptidase M
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTGF connective tissue growth factor
CTH cystathionine gamma-lyase
CXCR4 chemokine (C-X-C motif) receptor 4
CYR61 cysteine-rich, angiogenic inducer, 61
DENND3 DENN/MADD domain containing 3
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
EGR2 early growth response 2
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ELOVL4 ELOVL fatty acid elongase 4
EXT1 exostosin glycosyltransferase 1
FABP4 fatty acid binding protein 4, adipocyte
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GTF2B general transcription factor IIB
H1FX H1 histone family, member X
HSPA2 heat shock 70kDa protein 2
IL11 interleukin 11
IL1RAP interleukin 1 receptor accessory protein
IL7 interleukin 7
INSIG1 insulin induced gene 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIF16B kinesin family member 16B
LINC00341 long intergenic non-protein coding RNA 341
LMCD1 LIM and cysteine-rich domains 1
LPCAT3 lysophosphatidylcholine acyltransferase 3
MCTP1 multiple C2 domains, transmembrane 1
MLF1 myeloid leukemia factor 1
MMP1 matrix metallopeptidase 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NEU1 sialidase 1 (lysosomal sialidase)
NPC1 Niemann-Pick disease, type C1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUP62CL nucleoporin 62kDa C-terminal like
OASL 2'-5'-oligoadenylate synthetase-like
PCDH9 protocadherin 9
PDE4DIP phosphodiesterase 4D interacting protein
PELI1 pellino E3 ubiquitin protein ligase 1
PLA2G15 phospholipase A2, group XV
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB8B RAB8B, member RAS oncogene family
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS4 regulator of G-protein signaling 4
RHOB ras homolog family member B
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RUNDC3B RUN domain containing 3B
SEPP1 selenoprotein P, plasma, 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2
SORBS1 sorbin and SH3 domain containing 1
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
SSBP2 single-stranded DNA binding protein 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STARD5 StAR-related lipid transfer (START) domain containing 5
STC1 stanniocalcin 1
STK17B serine/threonine kinase 17b
STK4 serine/threonine kinase 4
STOM stomatin
SYT1 synaptotagmin I
SYT11 synaptotagmin XI
TAOK3 TAO kinase 3
TBPL1 TBP-like 1
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TPST2 tyrosylprotein sulfotransferase 2
TRAFD1 TRAF-type zinc finger domain containing 1
TUBB2B tubulin, beta 2B class IIb
TUFT1 tuftelin 1
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
ZC3H12A zinc finger CCCH-type containing 12A

decreased expression

Symbol Name
ADNP activity-dependent neuroprotector homeobox
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARSJ arylsulfatase family, member J
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BANP BTG3 associated nuclear protein
BCAR3 breast cancer anti-estrogen resistance 3
BHLHE41 basic helix-loop-helix family, member e41
C19ORF40 chromosome 19 open reading frame 40
C19ORF54 chromosome 19 open reading frame 54
CASD1 CAS1 domain containing 1
CBR3 carbonyl reductase 3
CDK5RAP2 CDK5 regulatory subunit associated protein 2
COA7 cytochrome c oxidase assembly factor 7 (putative)
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CTCF CCCTC-binding factor (zinc finger protein)
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DEPDC1 DEP domain containing 1
DTWD1 DTW domain containing 1
DUSP4 dual specificity phosphatase 4
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EXOSC10 exosome component 10
FAM169A family with sequence similarity 169, member A
FAM57A family with sequence similarity 57, member A
FJX1 four jointed box 1 (Drosophila)
FOSL1 FOS-like antigen 1
FOXA1 forkhead box A1
FST follistatin
GBX2 gastrulation brain homeobox 2
GPR87 G protein-coupled receptor 87
GRPR gastrin-releasing peptide receptor
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
H2AFY2 H2A histone family, member Y2
HAS2 hyaluronan synthase 2
HDAC7 histone deacetylase 7
HMGA2 high mobility group AT-hook 2
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
INHBB inhibin, beta B
ITPKB inositol-trisphosphate 3-kinase B
KAT6B K(lysine) acetyltransferase 6B
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KDM4D lysine (K)-specific demethylase 4D
KEAP1 kelch-like ECH-associated protein 1
LIF leukemia inhibitory factor
LMNB1 lamin B1
LPAR1 lysophosphatidic acid receptor 1
LRIF1 ligand dependent nuclear receptor interacting factor 1
LRRC37A3 leucine rich repeat containing 37, member A3
LRRC41 leucine rich repeat containing 41
LUC7L2 LUC7-like 2 (S. cerevisiae)
MEPCE methylphosphate capping enzyme
METTL4 methyltransferase like 4
MLPH melanophilin
MSL1 male-specific lethal 1 homolog (Drosophila)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NMI N-myc (and STAT) interactor
NOD1 nucleotide-binding oligomerization domain containing 1
NOL12 nucleolar protein 12
NR2F1 nuclear receptor subfamily 2, group F, member 1
NRIP1 nuclear receptor interacting protein 1
NUP62 nucleoporin 62kDa
PALMD palmdelphin
PLAU plasminogen activator, urokinase
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLK1 polo-like kinase 1
PPAP2B phosphatidic acid phosphatase type 2B
RBM23 RNA binding motif protein 23
RBM39 RNA binding motif protein 39
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RIN2 Ras and Rab interactor 2
RNF126P1 ring finger protein 126 pseudogene 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SFMBT1 Scm-like with four mbt domains 1
SH2D4A SH2 domain containing 4A
SIM2 single-minded family bHLH transcription factor 2
SMAGP small cell adhesion glycoprotein
SMG9 SMG9 nonsense mediated mRNA decay factor
SOX12 SRY (sex determining region Y)-box 12
SRSF4 serine/arginine-rich splicing factor 4
STBD1 starch binding domain 1
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SYNPO synaptopodin
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TOE1 target of EGR1, member 1 (nuclear)
TRIB3 tribbles pseudokinase 3
VEGFC vascular endothelial growth factor C
WNT7A wingless-type MMTV integration site family, member 7A
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial
ZBED1 zinc finger, BED-type containing 1
ZC3H4 zinc finger CCCH-type containing 4
ZC3H7A zinc finger CCCH-type containing 7A
ZCCHC10 zinc finger, CCHC domain containing 10
ZFHX3 zinc finger homeobox 3
ZNF165 zinc finger protein 165
ZNF248 zinc finger protein 248
ZNF358 zinc finger protein 358
ZNF532 zinc finger protein 532
ZNF692 zinc finger protein 692
ZNF787 zinc finger protein 787
ZNF804A zinc finger protein 804A
ZSCAN31 zinc finger and SCAN domain containing 31