trichostatin A-6434 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the trichostatin A-6434 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ACOT7 acyl-CoA thioesterase 7
ACSBG1 acyl-CoA synthetase bubblegum family member 1
AHNAK2 AHNAK nucleoprotein 2
AKAP12 A kinase (PRKA) anchor protein 12
ALDOC aldolase C, fructose-bisphosphate
ARMCX2 armadillo repeat containing, X-linked 2
BAIAP3 BAI1-associated protein 3
CASC1 cancer susceptibility candidate 1
CCDC28A coiled-coil domain containing 28A
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDH15 cadherin 15, type 1, M-cadherin (myotubule)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CLGN calmegin
CORO1A coronin, actin binding protein, 1A
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTSV cathepsin V
CXADR coxsackie virus and adenovirus receptor
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DOCK4 dedicator of cytokinesis 4
DPYSL4 dihydropyrimidinase-like 4
EFNA3 ephrin-A3
EFNB3 ephrin-B3
EGR1 early growth response 1
ELOVL4 ELOVL fatty acid elongase 4
EPOR erythropoietin receptor
FAM13A family with sequence similarity 13, member A
FAM46C family with sequence similarity 46, member C
FKBP1B FK506 binding protein 1B, 12.6 kDa
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GABARAPL1 GABA(A) receptor-associated protein like 1
GEM GTP binding protein overexpressed in skeletal muscle
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GLDC glycine dehydrogenase (decarboxylating)
GLRX glutaredoxin (thioltransferase)
GRK5 G protein-coupled receptor kinase 5
GTF2B general transcription factor IIB
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HSPA2 heat shock 70kDa protein 2
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IRF7 interferon regulatory factor 7
ITM2C integral membrane protein 2C
KIF21B kinesin family member 21B
KLHL24 kelch-like family member 24
LIMA1 LIM domain and actin binding 1
LINC00341 long intergenic non-protein coding RNA 341
MAP1B microtubule-associated protein 1B
MAST3 microtubule associated serine/threonine kinase 3
MLF1 myeloid leukemia factor 1
MMD monocyte to macrophage differentiation-associated
MUC3B mucin 3B, cell surface associated
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NPC1 Niemann-Pick disease, type C1
NXN nucleoredoxin
OASL 2'-5'-oligoadenylate synthetase-like
OPTN optineurin
PADI3 peptidyl arginine deiminase, type III
PDE4DIP phosphodiesterase 4D interacting protein
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PKNOX2 PBX/knotted 1 homeobox 2
PLK3 polo-like kinase 3
PMEL premelanosome protein
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTRF polymerase I and transcript release factor
RAI2 retinoic acid induced 2
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
RPL3L ribosomal protein L3-like
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RUNDC3B RUN domain containing 3B
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPP1 selenoprotein P, plasma, 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SIRT4 sirtuin 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SPAG9 sperm associated antigen 9
SPEF1 sperm flagellar 1
STK17A serine/threonine kinase 17a
SYT11 synaptotagmin XI
TBXA2R thromboxane A2 receptor
TIMP3 TIMP metallopeptidase inhibitor 3
TUFT1 tuftelin 1
ULBP2 UL16 binding protein 2
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WDR47 WD repeat domain 47
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZBTB48 zinc finger and BTB domain containing 48
ZCCHC24 zinc finger, CCHC domain containing 24
ZDHHC11 zinc finger, DHHC-type containing 11

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADNP activity-dependent neuroprotector homeobox
AKAP8 A kinase (PRKA) anchor protein 8
AMIGO2 adhesion molecule with Ig-like domain 2
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
BAGE B melanoma antigen
BANP BTG3 associated nuclear protein
BATF basic leucine zipper transcription factor, ATF-like
BCAR3 breast cancer anti-estrogen resistance 3
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C9ORF91 chromosome 9 open reading frame 91
CALHM2 calcium homeostasis modulator 2
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CBR3 carbonyl reductase 3
CCND1 cyclin D1
CCNO cyclin O
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CHKB choline kinase beta
CLDN9 claudin 9
COA7 cytochrome c oxidase assembly factor 7 (putative)
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DHRS3 dehydrogenase/reductase (SDR family) member 3
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
E2F3 E2F transcription factor 3
EFNA1 ephrin-A1
EXOSC10 exosome component 10
FAM57A family with sequence similarity 57, member A
FJX1 four jointed box 1 (Drosophila)
FOXA1 forkhead box A1
GATA3 GATA binding protein 3
GMEB1 glucocorticoid modulatory element binding protein 1
GMEB2 glucocorticoid modulatory element binding protein 2
GTF2IRD1 GTF2I repeat domain containing 1
HIST1H1D histone cluster 1, H1d
HMGXB4 HMG box domain containing 4
HOXC11 homeobox C11
HOXC13 homeobox C13
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
IRX5 iroquois homeobox 5
ITPKB inositol-trisphosphate 3-kinase B
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KEAP1 kelch-like ECH-associated protein 1
LOC100287590 uncharacterized LOC100287590
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LY6G5C lymphocyte antigen 6 complex, locus G5C
MEPCE methylphosphate capping enzyme
METTL8 methyltransferase like 8
MEX3C mex-3 RNA binding family member C
MID1IP1 MID1 interacting protein 1
MSL1 male-specific lethal 1 homolog (Drosophila)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NPY1R neuropeptide Y receptor Y1
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRIP1 nuclear receptor interacting protein 1
NUAK1 NUAK family, SNF1-like kinase, 1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PAGR1 PAXIP1 associated glutamate-rich protein 1
PPAN peter pan homolog (Drosophila)
PRR15L proline rich 15-like
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM23 RNA binding motif protein 23
RNF126P1 ring finger protein 126 pseudogene 1
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SETD1B SET domain containing 1B
SFMBT1 Scm-like with four mbt domains 1
SIX1 SIX homeobox 1
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMAD7 SMAD family member 7
SOX12 SRY (sex determining region Y)-box 12
SRSF4 serine/arginine-rich splicing factor 4
STBD1 starch binding domain 1
STC2 stanniocalcin 2
TGIF1 TGFB-induced factor homeobox 1
TRAF3IP2 TRAF3 interacting protein 2
TRIB3 tribbles pseudokinase 3
TRIM16 tripartite motif containing 16
TSKU tsukushi, small leucine rich proteoglycan
UBTF upstream binding transcription factor, RNA polymerase I
WDR4 WD repeat domain 4
XBP1 X-box binding protein 1
YAP1 Yes-associated protein 1
ZBED1 zinc finger, BED-type containing 1
ZBTB38 zinc finger and BTB domain containing 38
ZC3H4 zinc finger CCCH-type containing 4
ZFHX3 zinc finger homeobox 3
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF573 zinc finger protein 573
ZNF787 zinc finger protein 787
ZNHIT2 zinc finger, HIT-type containing 2