trichostatin A-6340 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the trichostatin A-6340 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ADM adrenomedullin
ADRB2 adrenoceptor beta 2, surface
AGTR1 angiotensin II receptor, type 1
ALAS1 5'-aminolevulinate synthase 1
ANGPTL4 angiopoietin-like 4
AQP3 aquaporin 3 (Gill blood group)
ARG2 arginase 2
ASMTL acetylserotonin O-methyltransferase-like
BAMBI BMP and activin membrane-bound inhibitor
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C16ORF45 chromosome 16 open reading frame 45
C1ORF95 chromosome 1 open reading frame 95
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CFAP69 cilia and flagella associated protein 69
CORO1A coronin, actin binding protein, 1A
CREB3L1 cAMP responsive element binding protein 3-like 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTGF connective tissue growth factor
CTH cystathionine gamma-lyase
CXCR4 chemokine (C-X-C motif) receptor 4
CYFIP2 cytoplasmic FMR1 interacting protein 2
CYR61 cysteine-rich, angiogenic inducer, 61
DENND3 DENN/MADD domain containing 3
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
EFNA3 ephrin-A3
EFNB2 ephrin-B2
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
FABP4 fatty acid binding protein 4, adipocyte
FADS3 fatty acid desaturase 3
FAM134B family with sequence similarity 134, member B
FYN FYN proto-oncogene, Src family tyrosine kinase
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GLS glutaminase
GMCL1 germ cell-less, spermatogenesis associated 1
GTF2B general transcription factor IIB
H1F0 H1 histone family, member 0
H1FX H1 histone family, member X
HOXA1 homeobox A1
IL1RAP interleukin 1 receptor accessory protein
IRF6 interferon regulatory factor 6
IRS2 insulin receptor substrate 2
KAZN kazrin, periplakin interacting protein
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIAA0895 KIAA0895
KIF5C kinesin family member 5C
LMCD1 LIM and cysteine-rich domains 1
LPPR4 lipid phosphate phosphatase-related protein type 4
MAK male germ cell-associated kinase
MAP2K3 mitogen-activated protein kinase kinase 3
MEGF9 multiple EGF-like-domains 9
MERTK MER proto-oncogene, tyrosine kinase
MLF1 myeloid leukemia factor 1
MMP1 matrix metallopeptidase 1
MMP16 matrix metallopeptidase 16 (membrane-inserted)
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NEU1 sialidase 1 (lysosomal sialidase)
NR4A2 nuclear receptor subfamily 4, group A, member 2
PCDH9 protocadherin 9
PDE4DIP phosphodiesterase 4D interacting protein
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PLK2 polo-like kinase 2
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAI2 retinoic acid induced 2
RGCC regulator of cell cycle
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS4 regulator of G-protein signaling 4
RNF19B ring finger protein 19B
RNF24 ring finger protein 24
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL2 SH3-domain GRB2-like 2
SH3GL3 SH3-domain GRB2-like 3
SLC25A44 solute carrier family 25, member 44
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
SORBS1 sorbin and SH3 domain containing 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STC1 stanniocalcin 1
SYT1 synaptotagmin I
TAOK3 TAO kinase 3
TBPL1 TBP-like 1
TMSB15A thymosin beta 15a
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TPMT thiopurine S-methyltransferase
TRAFD1 TRAF-type zinc finger domain containing 1
TUBB2B tubulin, beta 2B class IIb
TUFT1 tuftelin 1
USB1 U6 snRNA biogenesis 1
USP20 ubiquitin specific peptidase 20
WDR19 WD repeat domain 19
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
ACIN1 apoptotic chromatin condensation inducer 1
ADNP activity-dependent neuroprotector homeobox
ADORA2B adenosine A2b receptor
ARSJ arylsulfatase family, member J
BCAR3 breast cancer anti-estrogen resistance 3
BCL7A B-cell CLL/lymphoma 7A
C19ORF54 chromosome 19 open reading frame 54
CASD1 CAS1 domain containing 1
CBR3 carbonyl reductase 3
CCDC59 coiled-coil domain containing 59
CDC7 cell division cycle 7
CHST10 carbohydrate sulfotransferase 10
CLCF1 cardiotrophin-like cytokine factor 1
COA7 cytochrome c oxidase assembly factor 7 (putative)
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CUL1 cullin 1
DCTN4 dynactin 4 (p62)
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
E2F8 E2F transcription factor 8
EMG1 EMG1 N1-specific pseudouridine methyltransferase
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
ETV4 ets variant 4
FJX1 four jointed box 1 (Drosophila)
FOSL1 FOS-like antigen 1
FST follistatin
GBX2 gastrulation brain homeobox 2
HAS2 hyaluronan synthase 2
HIRIP3 HIRA interacting protein 3
HMGA2 high mobility group AT-hook 2
INHBB inhibin, beta B
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IPP intracisternal A particle-promoted polypeptide
KEAP1 kelch-like ECH-associated protein 1
KIF14 kinesin family member 14
KLF11 Kruppel-like factor 11
LHX6 LIM homeobox 6
LIF leukemia inhibitory factor
LMNB1 lamin B1
LPAR1 lysophosphatidic acid receptor 1
LRIF1 ligand dependent nuclear receptor interacting factor 1
LRRC41 leucine rich repeat containing 41
LUC7L2 LUC7-like 2 (S. cerevisiae)
MARC1 mitochondrial amidoxime reducing component 1
MCRS1 microspherule protein 1
MEPCE methylphosphate capping enzyme
MFSD5 major facilitator superfamily domain containing 5
MISP mitotic spindle positioning
MPDU1 mannose-P-dolichol utilization defect 1
MSL1 male-specific lethal 1 homolog (Drosophila)
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NINJ1 ninjurin 1
NLRX1 NLR family member X1
NME6 NME/NM23 nucleoside diphosphate kinase 6
NMI N-myc (and STAT) interactor
NR2C2 nuclear receptor subfamily 2, group C, member 2
NRIP1 nuclear receptor interacting protein 1
PARP12 poly (ADP-ribose) polymerase family, member 12
PCGF1 polycomb group ring finger 1
PEF1 penta-EF-hand domain containing 1
PHF11 PHD finger protein 11
PIAS3 protein inhibitor of activated STAT, 3
PLAU plasminogen activator, urokinase
POGK pogo transposable element with KRAB domain
PPAP2B phosphatidic acid phosphatase type 2B
RBM22 RNA binding motif protein 22
RBM39 RNA binding motif protein 39
RCOR3 REST corepressor 3
RIN2 Ras and Rab interactor 2
RPAP1 RNA polymerase II associated protein 1
SCAF8 SR-related CTD-associated factor 8
SETD1B SET domain containing 1B
SFMBT1 Scm-like with four mbt domains 1
SIM2 single-minded family bHLH transcription factor 2
SMAGP small cell adhesion glycoprotein
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SMYD5 SMYD family member 5
SRSF4 serine/arginine-rich splicing factor 4
STXBP3 syntaxin binding protein 3
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TARBP2 TAR (HIV-1) RNA binding protein 2
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TMED1 transmembrane emp24 protein transport domain containing 1
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TOE1 target of EGR1, member 1 (nuclear)
TRIB3 tribbles pseudokinase 3
TUBGCP5 tubulin, gamma complex associated protein 5
URGCP upregulator of cell proliferation
USP21 ubiquitin specific peptidase 21
VEGFC vascular endothelial growth factor C
VWA9 von Willebrand factor A domain containing 9
WDR74 WD repeat domain 74
ZBTB3 zinc finger and BTB domain containing 3
ZC3H4 zinc finger CCCH-type containing 4
ZCCHC10 zinc finger, CCHC domain containing 10
ZNF239 zinc finger protein 239
ZNF33B zinc finger protein 33B
ZNF692 zinc finger protein 692
ZNF85 zinc finger protein 85