trichostatin A-6316 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the trichostatin A-6316 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ADM adrenomedullin
ADRB2 adrenoceptor beta 2, surface
AGTR1 angiotensin II receptor, type 1
AQP3 aquaporin 3 (Gill blood group)
ARG2 arginase 2
ARHGAP6 Rho GTPase activating protein 6
ASMTL acetylserotonin O-methyltransferase-like
AVPI1 arginine vasopressin-induced 1
BAMBI BMP and activin membrane-bound inhibitor
BIRC3 baculoviral IAP repeat containing 3
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C18ORF8 chromosome 18 open reading frame 8
C1ORF116 chromosome 1 open reading frame 116
CA5B carbonic anhydrase VB, mitochondrial
CCNA1 cyclin A1
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CFAP69 cilia and flagella associated protein 69
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLDN1 claudin 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTGF connective tissue growth factor
CTH cystathionine gamma-lyase
CTNS cystinosin, lysosomal cystine transporter
CXCR4 chemokine (C-X-C motif) receptor 4
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
DUSP5 dual specificity phosphatase 5
EFNA3 ephrin-A3
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EPPK1 epiplakin 1
FABP4 fatty acid binding protein 4, adipocyte
FAM69A family with sequence similarity 69, member A
FLRT3 fibronectin leucine rich transmembrane protein 3
FYN FYN proto-oncogene, Src family tyrosine kinase
GABARAPL1 GABA(A) receptor-associated protein like 1
GLCE glucuronic acid epimerase
GLS glutaminase
GPRC5A G protein-coupled receptor, class C, group 5, member A
GTF2B general transcription factor IIB
H1FX H1 histone family, member X
HOXA1 homeobox A1
IRF6 interferon regulatory factor 6
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIAA0895 KIAA0895
KIAA0922 KIAA0922
KIF5C kinesin family member 5C
LINC00341 long intergenic non-protein coding RNA 341
LMCD1 LIM and cysteine-rich domains 1
LPPR4 lipid phosphate phosphatase-related protein type 4
MAK male germ cell-associated kinase
MAP2K3 mitogen-activated protein kinase kinase 3
MCTP1 multiple C2 domains, transmembrane 1
MERTK MER proto-oncogene, tyrosine kinase
MLF1 myeloid leukemia factor 1
MMP1 matrix metallopeptidase 1
NBEA neurobeachin
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NME5 NME/NM23 family member 5
NRXN3 neurexin 3
PAIP2B poly(A) binding protein interacting protein 2B
PCDH9 protocadherin 9
PDE4DIP phosphodiesterase 4D interacting protein
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PKP2 plakophilin 2
PPL periplakin
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTCH1 patched 1
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAI2 retinoic acid induced 2
RGCC regulator of cell cycle
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS4 regulator of G-protein signaling 4
RNF24 ring finger protein 24
SAT1 spermidine/spermine N1-acetyltransferase 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SLC25A44 solute carrier family 25, member 44
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
SQLE squalene epoxidase
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STC1 stanniocalcin 1
STON1 stonin 1
SYT1 synaptotagmin I
TMSB15A thymosin beta 15a
TPMT thiopurine S-methyltransferase
TRAFD1 TRAF-type zinc finger domain containing 1
TUBB2B tubulin, beta 2B class IIb
TUFT1 tuftelin 1
UGCG UDP-glucose ceramide glucosyltransferase

decreased expression

Symbol Name
ADNP activity-dependent neuroprotector homeobox
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARMC6 armadillo repeat containing 6
ATF1 activating transcription factor 1
BCAR3 breast cancer anti-estrogen resistance 3
BCL7A B-cell CLL/lymphoma 7A
C19ORF54 chromosome 19 open reading frame 54
C9ORF91 chromosome 9 open reading frame 91
CASD1 CAS1 domain containing 1
CCDC59 coiled-coil domain containing 59
CLCF1 cardiotrophin-like cytokine factor 1
COA7 cytochrome c oxidase assembly factor 7 (putative)
COIL coilin
COQ4 coenzyme Q4
CUL1 cullin 1
DENND4B DENN/MADD domain containing 4B
DEPDC1 DEP domain containing 1
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
E2F8 E2F transcription factor 8
E4F1 E4F transcription factor 1
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
FJX1 four jointed box 1 (Drosophila)
FOSL1 FOS-like antigen 1
FOXA1 forkhead box A1
FST follistatin
GBX2 gastrulation brain homeobox 2
H2AFY2 H2A histone family, member Y2
HARS2 histidyl-tRNA synthetase 2, mitochondrial
HAS2 hyaluronan synthase 2
HIRIP3 HIRA interacting protein 3
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2
HMGA2 high mobility group AT-hook 2
HMGXB4 HMG box domain containing 4
IL7R interleukin 7 receptor
INHBB inhibin, beta B
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
KAT6B K(lysine) acetyltransferase 6B
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KEAP1 kelch-like ECH-associated protein 1
LIF leukemia inhibitory factor
LINC00339 long intergenic non-protein coding RNA 339
LMNB1 lamin B1
LPAR1 lysophosphatidic acid receptor 1
LRRC41 leucine rich repeat containing 41
LUC7L2 LUC7-like 2 (S. cerevisiae)
MALL mal, T-cell differentiation protein-like
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MCM9 minichromosome maintenance complex component 9
MCRS1 microspherule protein 1
MEPCE methylphosphate capping enzyme
METTL1 methyltransferase like 1
MSL1 male-specific lethal 1 homolog (Drosophila)
MTPAP mitochondrial poly(A) polymerase
MYD88 myeloid differentiation primary response 88
NLRX1 NLR family member X1
NME6 NME/NM23 nucleoside diphosphate kinase 6
NR1H2 nuclear receptor subfamily 1, group H, member 2
NR2C2 nuclear receptor subfamily 2, group C, member 2
NRIP1 nuclear receptor interacting protein 1
PALMD palmdelphin
PARP4 poly (ADP-ribose) polymerase family, member 4
PCNT pericentrin
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PHF11 PHD finger protein 11
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLK1 polo-like kinase 1
POGK pogo transposable element with KRAB domain
PPAN peter pan homolog (Drosophila)
PPAP2B phosphatidic acid phosphatase type 2B
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
QTRT1 queuine tRNA-ribosyltransferase 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGS19 regulator of G-protein signaling 19
RIN2 Ras and Rab interactor 2
SCAF8 SR-related CTD-associated factor 8
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SETBP1 SET binding protein 1
SFMBT1 Scm-like with four mbt domains 1
SIM2 single-minded family bHLH transcription factor 2
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SRSF4 serine/arginine-rich splicing factor 4
STAG1 stromal antigen 1
STXBP3 syntaxin binding protein 3
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TMEM11 transmembrane protein 11
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TRIB3 tribbles pseudokinase 3
TRIM16 tripartite motif containing 16
UBXN8 UBX domain protein 8
USP21 ubiquitin specific peptidase 21
VEGFC vascular endothelial growth factor C
WDR74 WD repeat domain 74
ZBED1 zinc finger, BED-type containing 1
ZC3H4 zinc finger CCCH-type containing 4
ZNF165 zinc finger protein 165
ZNF787 zinc finger protein 787