trichostatin A-6276 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the trichostatin A-6276 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADD3 adducin 3 (gamma)
ADM adrenomedullin
AHNAK2 AHNAK nucleoprotein 2
ALDOC aldolase C, fructose-bisphosphate
ARL4C ADP-ribosylation factor-like 4C
ARMCX2 armadillo repeat containing, X-linked 2
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
BAIAP2 BAI1-associated protein 2
BEX4 brain expressed, X-linked 4
BMP7 bone morphogenetic protein 7
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CCDC28A coiled-coil domain containing 28A
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CLGN calmegin
CORO1A coronin, actin binding protein, 1A
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CXADR coxsackie virus and adenovirus receptor
CXCR4 chemokine (C-X-C motif) receptor 4
CYLD cylindromatosis (turban tumor syndrome)
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DEGS1 delta(4)-desaturase, sphingolipid 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLX2 distal-less homeobox 2
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DPYSL4 dihydropyrimidinase-like 4
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFNA3 ephrin-A3
EFNB3 ephrin-B3
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GEM GTP binding protein overexpressed in skeletal muscle
GLRX glutaredoxin (thioltransferase)
GTF2B general transcription factor IIB
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
KIAA0930 KIAA0930
KIF5C kinesin family member 5C
LIMA1 LIM domain and actin binding 1
LMBR1L limb development membrane protein 1-like
LMCD1 LIM and cysteine-rich domains 1
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MAST3 microtubule associated serine/threonine kinase 3
MLF1 myeloid leukemia factor 1
MMD monocyte to macrophage differentiation-associated
MXI1 MAX interactor 1, dimerization protein
NDRG4 NDRG family member 4
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NES nestin
NME5 NME/NM23 family member 5
NME7 NME/NM23 family member 7
NPC1 Niemann-Pick disease, type C1
NXN nucleoredoxin
OPTN optineurin
PADI3 peptidyl arginine deiminase, type III
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PMEL premelanosome protein
PPARD peroxisome proliferator-activated receptor delta
PRPH peripherin
PTRF polymerase I and transcript release factor
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB40B RAB40B, member RAS oncogene family
RAI2 retinoic acid induced 2
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
RNFT2 ring finger protein, transmembrane 2
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RTN2 reticulon 2
RUNDC3B RUN domain containing 3B
SAT1 spermidine/spermine N1-acetyltransferase 1
SCAPER S-phase cyclin A-associated protein in the ER
SEPP1 selenoprotein P, plasma, 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SIRT4 sirtuin 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SNN stannin
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STON1 stonin 1
STXBP1 syntaxin binding protein 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
SYBU syntabulin (syntaxin-interacting)
SYT11 synaptotagmin XI
TBXA2R thromboxane A2 receptor
TRIM2 tripartite motif containing 2
TUBA4A tubulin, alpha 4a
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
ULBP2 UL16 binding protein 2
WDR19 WD repeat domain 19
WDR47 WD repeat domain 47
ZCCHC24 zinc finger, CCHC domain containing 24
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF10 zinc finger protein 10
ZNF204P zinc finger protein 204, pseudogene
ZNF235 zinc finger protein 235

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADNP activity-dependent neuroprotector homeobox
ANKRD10 ankyrin repeat domain 10
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARAF A-Raf proto-oncogene, serine/threonine kinase
BANP BTG3 associated nuclear protein
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C1ORF106 chromosome 1 open reading frame 106
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCDC94 coiled-coil domain containing 94
CCND1 cyclin D1
CCNJ cyclin J
CCNL2 cyclin L2
CERS2 ceramide synthase 2
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CUL1 cullin 1
DDRGK1 DDRGK domain containing 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
DKK1 dickkopf WNT signaling pathway inhibitor 1
FAM57A family with sequence similarity 57, member A
FJX1 four jointed box 1 (Drosophila)
FOXD1 forkhead box D1
GABPB1 GA binding protein transcription factor, beta subunit 1
GATA3 GATA binding protein 3
GLMN glomulin, FKBP associated protein
GRWD1 glutamate-rich WD repeat containing 1
GTF2I general transcription factor IIi
GTF2IRD1 GTF2I repeat domain containing 1
HIRIP3 HIRA interacting protein 3
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
IRX5 iroquois homeobox 5
JADE1 jade family PHD finger 1
KAT2A K(lysine) acetyltransferase 2A
KCTD15 potassium channel tetramerization domain containing 15
KEAP1 kelch-like ECH-associated protein 1
KIF15 kinesin family member 15
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LUC7L2 LUC7-like 2 (S. cerevisiae)
LY6G5C lymphocyte antigen 6 complex, locus G5C
MAGEF1 melanoma antigen family F1
MCM9 minichromosome maintenance complex component 9
MEPCE methylphosphate capping enzyme
MLPH melanophilin
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NRIP1 nuclear receptor interacting protein 1
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
NUBP1 nucleotide binding protein 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PEF1 penta-EF-hand domain containing 1
PHLDA3 pleckstrin homology-like domain, family A, member 3
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLK1 polo-like kinase 1
POGK pogo transposable element with KRAB domain
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRNP prion protein
PRR3 proline rich 3
PRR7 proline rich 7 (synaptic)
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM23 RNA binding motif protein 23
REV1 REV1, polymerase (DNA directed)
RHOBTB1 Rho-related BTB domain containing 1
RPRD2 regulation of nuclear pre-mRNA domain containing 2
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SCRN1 secernin 1
SETD1B SET domain containing 1B
SFMBT1 Scm-like with four mbt domains 1
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SPIN1 spindlin 1
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SRSF4 serine/arginine-rich splicing factor 4
STC2 stanniocalcin 2
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TDRD3 tudor domain containing 3
TGIF1 TGFB-induced factor homeobox 1
TRIB3 tribbles pseudokinase 3
TRIM16 tripartite motif containing 16
TRIM8 tripartite motif containing 8
TRPS1 trichorhinophalangeal syndrome I
TSKU tsukushi, small leucine rich proteoglycan
UBXN8 UBX domain protein 8
WBSCR16 Williams-Beuren syndrome chromosome region 16
WDR74 WD repeat domain 74
XBP1 X-box binding protein 1
YAP1 Yes-associated protein 1
ZBED5 zinc finger, BED-type containing 5
ZC3H4 zinc finger CCCH-type containing 4
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1
ZNF408 zinc finger protein 408
ZNF562 zinc finger protein 562
ZNF692 zinc finger protein 692
ZNF787 zinc finger protein 787