trichostatin A-6193 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the trichostatin A-6193 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ALDH8A1 aldehyde dehydrogenase 8 family, member A1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
AREG amphiregulin
ARG2 arginase 2
ARHGAP29 Rho GTPase activating protein 29
ARMC9 armadillo repeat containing 9
ASMTL acetylserotonin O-methyltransferase-like
BLVRA biliverdin reductase A
C16ORF45 chromosome 16 open reading frame 45
C5ORF45 chromosome 5 open reading frame 45
CD59 CD59 molecule, complement regulatory protein
CEP104 centrosomal protein 104kDa
CHN2 chimerin 2
CPM carboxypeptidase M
CPNE3 copine III
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSRP2 cysteine and glycine-rich protein 2
CXADR coxsackie virus and adenovirus receptor
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DSP desmoplakin
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFNA3 ephrin-A3
EFNA4 ephrin-A4
EFNB2 ephrin-B2
ENAH enabled homolog (Drosophila)
ENO2 enolase 2 (gamma, neuronal)
EPAS1 endothelial PAS domain protein 1
F11R F11 receptor
FAM134B family with sequence similarity 134, member B
FAM49A family with sequence similarity 49, member A
FAM69A family with sequence similarity 69, member A
FGF9 fibroblast growth factor 9
FGFR1 fibroblast growth factor receptor 1
FKBP1B FK506 binding protein 1B, 12.6 kDa
GCH1 GTP cyclohydrolase 1
GIPC1 GIPC PDZ domain containing family, member 1
GLRX glutaredoxin (thioltransferase)
GRK5 G protein-coupled receptor kinase 5
H1F0 H1 histone family, member 0
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1
KIAA0040 KIAA0040
KIAA0226L KIAA0226-like
KIAA0513 KIAA0513
KIAA0895 KIAA0895
KIF3A kinesin family member 3A
KIF5C kinesin family member 5C
LAMP3 lysosomal-associated membrane protein 3
LHX2 LIM homeobox 2
MAN1A1 mannosidase, alpha, class 1A, member 1
MARCKS myristoylated alanine-rich protein kinase C substrate
MLF1 myeloid leukemia factor 1
MPZL1 myelin protein zero-like 1
MTCL1 microtubule crosslinking factor 1
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYH10 myosin, heavy chain 10, non-muscle
MYO6 myosin VI
NCAM1 neural cell adhesion molecule 1
NEU1 sialidase 1 (lysosomal sialidase)
PALLD palladin, cytoskeletal associated protein
PARD6A par-6 family cell polarity regulator alpha
PCDH9 protocadherin 9
PCLO piccolo presynaptic cytomatrix protein
PCYOX1 prenylcysteine oxidase 1
PDE4DIP phosphodiesterase 4D interacting protein
PDGFRL platelet-derived growth factor receptor-like
PEX1 peroxisomal biogenesis factor 1
PEX11A peroxisomal biogenesis factor 11 alpha
PGBD5 piggyBac transposable element derived 5
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLA2G12A phospholipase A2, group XIIA
PLS1 plastin 1
POR P450 (cytochrome) oxidoreductase
POU4F1 POU class 4 homeobox 1
RIMS3 regulating synaptic membrane exocytosis 3
RPGRIP1L RPGRIP1-like
SCG5 secretogranin V
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC46A3 solute carrier family 46, member 3
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
STAT4 signal transducer and activator of transcription 4
STXBP1 syntaxin binding protein 1
TBC1D16 TBC1 domain family, member 16
TPD52L1 tumor protein D52-like 1
TPMT thiopurine S-methyltransferase
TRIM2 tripartite motif containing 2
TSC2 tuberous sclerosis 2
TSPAN13 tetraspanin 13
TUBB2A tubulin, beta 2A class IIa
TUFT1 tuftelin 1
WDR19 WD repeat domain 19
ZC2HC1A zinc finger, C2HC-type containing 1A
ZSWIM8 zinc finger, SWIM-type containing 8

decreased expression

Symbol Name
ADNP activity-dependent neuroprotector homeobox
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ANKRD55 ankyrin repeat domain 55
ANP32A-IT1 ANP32A intronic transcript 1
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
APOBR apolipoprotein B receptor
ARRB1 arrestin, beta 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATP8B4 ATPase, class I, type 8B, member 4
BDH1 3-hydroxybutyrate dehydrogenase, type 1
C3AR1 complement component 3a receptor 1
CARD9 caspase recruitment domain family, member 9
CASD1 CAS1 domain containing 1
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCDC106 coiled-coil domain containing 106
CCDC94 coiled-coil domain containing 94
CCL2 chemokine (C-C motif) ligand 2
CCL4 chemokine (C-C motif) ligand 4
CCR2 chemokine (C-C motif) receptor 2
CD14 CD14 molecule
CD69 CD69 molecule
CLEC5A C-type lectin domain family 5, member A
CUX2 cut-like homeobox 2
CXORF21 chromosome X open reading frame 21
DOK2 docking protein 2, 56kDa
EMG1 EMG1 N1-specific pseudouridine methyltransferase
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM57A family with sequence similarity 57, member A
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FES FES proto-oncogene, tyrosine kinase
FGL2 fibrinogen-like 2
FGR FGR proto-oncogene, Src family tyrosine kinase
FMNL1 formin-like 1
FOSL1 FOS-like antigen 1
GFI1 growth factor independent 1 transcription repressor
GMIP GEM interacting protein
GPR18 G protein-coupled receptor 18
GRAMD1B GRAM domain containing 1B
GTF2I general transcription factor IIi
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HMHA1 histocompatibility (minor) HA-1
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IL1R2 interleukin 1 receptor, type II
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
JADE1 jade family PHD finger 1
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LAT2 linker for activation of T cells family, member 2
LPPR3 lipid phosphate phosphatase-related protein type 3
LTB lymphotoxin beta (TNF superfamily, member 3)
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MDFIC MyoD family inhibitor domain containing
METTL8 methyltransferase like 8
MOCOS molybdenum cofactor sulfurase
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MX1 MX dynamin-like GTPase 1
MX2 MX dynamin-like GTPase 2
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFE2 nuclear factor, erythroid 2
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NINJ2 ninjurin 2
NOD1 nucleotide-binding oligomerization domain containing 1
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPN7 protein tyrosine phosphatase, non-receptor type 7
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RGS19 regulator of G-protein signaling 19
RHOH ras homolog family member H
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
SH2D3C SH2 domain containing 3C
SIGLEC9 sialic acid binding Ig-like lectin 9
SLA Src-like-adaptor
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SOX12 SRY (sex determining region Y)-box 12
SPI1 Spi-1 proto-oncogene
STAR steroidogenic acute regulatory protein
TARP TCR gamma alternate reading frame protein
TERT telomerase reverse transcriptase
TET3 tet methylcytosine dioxygenase 3
TGM5 transglutaminase 5
TMED1 transmembrane emp24 protein transport domain containing 1
TOE1 target of EGR1, member 1 (nuclear)
TRIB3 tribbles pseudokinase 3
TRPM2 transient receptor potential cation channel, subfamily M, member 2
UCK2 uridine-cytidine kinase 2
WT1 Wilms tumor 1
ZBED1 zinc finger, BED-type containing 1
ZEB2 zinc finger E-box binding homeobox 2
ZFP36L2 ZFP36 ring finger protein-like 2
ZHX2 zinc fingers and homeoboxes 2
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF536 zinc finger protein 536
ZNF787 zinc finger protein 787
ZNF804A zinc finger protein 804A