trichostatin A-6171 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the trichostatin A-6171 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRL2 adhesion G protein-coupled receptor L2
AFF4 AF4/FMR2 family, member 4
AMIGO2 adhesion molecule with Ig-like domain 2
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARL15 ADP-ribosylation factor-like 15
ATHL1 ATH1, acid trehalase-like 1 (yeast)
BBS9 Bardet-Biedl syndrome 9
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BCL9 B-cell CLL/lymphoma 9
BICD1 bicaudal D homolog 1 (Drosophila)
C17ORF59 chromosome 17 open reading frame 59
CABP2 calcium binding protein 2
CBR3 carbonyl reductase 3
CD59 CD59 molecule, complement regulatory protein
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
CREM cAMP responsive element modulator
CRTAM cytotoxic and regulatory T cell molecule
CTNND2 catenin (cadherin-associated protein), delta 2
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DCAF17 DDB1 and CUL4 associated factor 17
DLG3 discs, large homolog 3 (Drosophila)
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DSP desmoplakin
DVL2 dishevelled segment polarity protein 2
ECI2 enoyl-CoA delta isomerase 2
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EFNB2 ephrin-B2
EPAS1 endothelial PAS domain protein 1
ETV1 ets variant 1
FADS3 fatty acid desaturase 3
FBXO4 F-box protein 4
FER fer (fps/fes related) tyrosine kinase
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FOXO1 forkhead box O1
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10
GAREM GRB2 associated, regulator of MAPK1
GAS1 growth arrest-specific 1
GP6 glycoprotein VI (platelet)
GPR19 G protein-coupled receptor 19
H1F0 H1 histone family, member 0
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HLF hepatic leukemia factor
IFT27 intraflagellar transport 27
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IGL immunoglobulin lambda locus
IL18 interleukin 18
ITGA6 integrin, alpha 6
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KIF5C kinesin family member 5C
KLRF1 killer cell lectin-like receptor subfamily F, member 1
LAMA4 laminin, alpha 4
LHX2 LIM homeobox 2
LRP6 low density lipoprotein receptor-related protein 6
LTBP2 latent transforming growth factor beta binding protein 2
MARCKS myristoylated alanine-rich protein kinase C substrate
MED25 mediator complex subunit 25
MR1 major histocompatibility complex, class I-related
MRC2 mannose receptor, C type 2
MSRB2 methionine sulfoxide reductase B2
NCAM1 neural cell adhesion molecule 1
NELL2 NEL-like 2 (chicken)
NEURL1 neuralized E3 ubiquitin protein ligase 1
NPY2R neuropeptide Y receptor Y2
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRCAM neuronal cell adhesion molecule
NXPE3 neurexophilin and PC-esterase domain family, member 3
OPRL1 opiate receptor-like 1
OPTN optineurin
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PALLD palladin, cytoskeletal associated protein
PCLO piccolo presynaptic cytomatrix protein
PDE4DIP phosphodiesterase 4D interacting protein
PGBD5 piggyBac transposable element derived 5
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLD3 phospholipase D family, member 3
PLS1 plastin 1
PPARD peroxisome proliferator-activated receptor delta
PRB4 proline-rich protein BstNI subfamily 4
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PVR poliovirus receptor
QPCT glutaminyl-peptide cyclotransferase
RAB3D RAB3D, member RAS oncogene family
RECK reversion-inducing-cysteine-rich protein with kazal motifs
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
THSD7A thrombospondin, type I, domain containing 7A
TLR7 toll-like receptor 7
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TPD52L1 tumor protein D52-like 1
TRIM9 tripartite motif containing 9
TSPAN13 tetraspanin 13
UST uronyl-2-sulfotransferase
VASH2 vasohibin 2
VPS13B vacuolar protein sorting 13 homolog B (yeast)

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACP5 acid phosphatase 5, tartrate resistant
ADGRG2 adhesion G protein-coupled receptor G2
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ALPK1 alpha-kinase 1
ANKRD40 ankyrin repeat domain 40
ANKZF1 ankyrin repeat and zinc finger domain containing 1
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
AXIN1 axin 1
BCAS3 breast carcinoma amplified sequence 3
BGLAP bone gamma-carboxyglutamate (gla) protein
BTBD18 BTB (POZ) domain containing 18
C16ORF59 chromosome 16 open reading frame 59
C1QTNF3 C1q and tumor necrosis factor related protein 3
CBX8 chromobox homolog 8
CCDC85C coiled-coil domain containing 85C
CCL20 chemokine (C-C motif) ligand 20
CCL21 chemokine (C-C motif) ligand 21
CD151 CD151 molecule (Raph blood group)
CDK20 cyclin-dependent kinase 20
CLCF1 cardiotrophin-like cytokine factor 1
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPA4 carboxypeptidase A4
CRABP2 cellular retinoic acid binding protein 2
CROT carnitine O-octanoyltransferase
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DUSP8 dual specificity phosphatase 8
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ERCC4 excision repair cross-complementation group 4
EXD3 exonuclease 3'-5' domain containing 3
FAM120C family with sequence similarity 120C
FAM86B1 family with sequence similarity 86, member B1
FLRT1 fibronectin leucine rich transmembrane protein 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GPR27 G protein-coupled receptor 27
GPR35 G protein-coupled receptor 35
GRWD1 glutamate-rich WD repeat containing 1
HIST1H2BO histone cluster 1, H2bo
HIST1H4A histone cluster 1, H4a
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFI44L interferon-induced protein 44-like
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
ITPKC inositol-trisphosphate 3-kinase C
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIF17 kinesin family member 17
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KLHL26 kelch-like family member 26
KRI1 KRI1 homolog (S. cerevisiae)
MATK megakaryocyte-associated tyrosine kinase
MPZ myelin protein zero
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYO15A myosin XVA
MYOZ1 myozenin 1
NARFL nuclear prelamin A recognition factor-like
NCS1 neuronal calcium sensor 1
NHEJ1 nonhomologous end-joining factor 1
NR1D2 nuclear receptor subfamily 1, group D, member 2
NSD1 nuclear receptor binding SET domain protein 1
NT5DC3 5'-nucleotidase domain containing 3
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OMG oligodendrocyte myelin glycoprotein
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PLP1 proteolipid protein 1
PRR4 proline rich 4 (lacrimal)
PRY PTPN13-like, Y-linked
PTCD1 pentatricopeptide repeat domain 1
PYCRL pyrroline-5-carboxylate reductase-like
PYGB phosphorylase, glycogen; brain
RAB33A RAB33A, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
REPS2 RALBP1 associated Eps domain containing 2
RGS19 regulator of G-protein signaling 19
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RPL23AP32 ribosomal protein L23a pseudogene 32
SCUBE3 signal peptide, CUB domain, EGF-like 3
SETD1A SET domain containing 1A
SLC16A6 solute carrier family 16, member 6
SOX21 SRY (sex determining region Y)-box 21
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STK16 serine/threonine kinase 16
TAOK1 TAO kinase 1
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
THRAP3 thyroid hormone receptor associated protein 3
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRAF4 TNF receptor-associated factor 4
TREM2 triggering receptor expressed on myeloid cells 2
TSPAN32 tetraspanin 32
TUBA4B tubulin, alpha 4b
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WNT10B wingless-type MMTV integration site family, member 10B
ZFHX4 zinc finger homeobox 4
ZNF137P zinc finger protein 137, pseudogene
ZNF324 zinc finger protein 324
ZSCAN31 zinc finger and SCAN domain containing 31