trichostatin A-6143 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the trichostatin A-6143 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACP6 acid phosphatase 6, lysophosphatidic
ANG angiogenin, ribonuclease, RNase A family, 5
ANK2 ankyrin 2, neuronal
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARMC9 armadillo repeat containing 9
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BAIAP2 BAI1-associated protein 2
BANK1 B-cell scaffold protein with ankyrin repeats 1
BIN1 bridging integrator 1
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
C11ORF16 chromosome 11 open reading frame 16
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast)
CASC1 cancer susceptibility candidate 1
CASP10 caspase 10, apoptosis-related cysteine peptidase
CD59 CD59 molecule, complement regulatory protein
CPM carboxypeptidase M
CREB3L1 cAMP responsive element binding protein 3-like 1
CRYGC crystallin, gamma C
CXADR coxsackie virus and adenovirus receptor
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DUSP4 dual specificity phosphatase 4
ECI2 enoyl-CoA delta isomerase 2
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ETV1 ets variant 1
FADS3 fatty acid desaturase 3
FAM13A family with sequence similarity 13, member A
FAM215A family with sequence similarity 215, member A (non-protein coding)
FAM49A family with sequence similarity 49, member A
FAM69A family with sequence similarity 69, member A
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FLOT1 flotillin 1
FNBP1L formin binding protein 1-like
FOXD1 forkhead box D1
FOXO1 forkhead box O1
GLRX glutaredoxin (thioltransferase)
H1F0 H1 histone family, member 0
HOXC5 homeobox C5
HTRA1 HtrA serine peptidase 1
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFT27 intraflagellar transport 27
IGSF3 immunoglobulin superfamily, member 3
INHBA inhibin, beta A
IQSEC1 IQ motif and Sec7 domain 1
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KIF5C kinesin family member 5C
KLK7 kallikrein-related peptidase 7
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KRT17 keratin 17, type I
LHX2 LIM homeobox 2
LINC00652 long intergenic non-protein coding RNA 652
LRP6 low density lipoprotein receptor-related protein 6
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAMLD1 mastermind-like domain containing 1
MAN1A1 mannosidase, alpha, class 1A, member 1
MARCKS myristoylated alanine-rich protein kinase C substrate
MCAM melanoma cell adhesion molecule
MPZL1 myelin protein zero-like 1
MREG melanoregulin
MXD4 MAX dimerization protein 4
MYH10 myosin, heavy chain 10, non-muscle
MYO1B myosin IB
NCAM1 neural cell adhesion molecule 1
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
ONECUT2 one cut homeobox 2
PADI1 peptidyl arginine deiminase, type I
PALLD palladin, cytoskeletal associated protein
PCGF2 polycomb group ring finger 2
PFN2 profilin 2
PLS1 plastin 1
POU4F1 POU class 4 homeobox 1
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
QPCT glutaminyl-peptide cyclotransferase
RGS5 regulator of G-protein signaling 5
RNASE4 ribonuclease, RNase A family, 4
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GLB2 SH3-domain GRB2-like endophilin B2
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOX4 SRY (sex determining region Y)-box 4
STAP1 signal transducing adaptor family member 1
TBC1D19 TBC1 domain family, member 19
TLN2 talin 2
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNIK TRAF2 and NCK interacting kinase
TPBG trophoblast glycoprotein
TPD52L1 tumor protein D52-like 1
TRIM2 tripartite motif containing 2
TRIM9 tripartite motif containing 9
TSPAN13 tetraspanin 13
TUBB2A tubulin, beta 2A class IIa
ULBP2 UL16 binding protein 2
VAV2 vav 2 guanine nucleotide exchange factor
VPS9D1 VPS9 domain containing 1
WLS wntless Wnt ligand secretion mediator
ZER1 zyg-11 related, cell cycle regulator
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ANKRD40 ankyrin repeat domain 40
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
ARHGAP10 Rho GTPase activating protein 10
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATAD2B ATPase family, AAA domain containing 2B
BGLAP bone gamma-carboxyglutamate (gla) protein
BTBD7 BTB (POZ) domain containing 7
C11ORF63 chromosome 11 open reading frame 63
C5AR1 complement component 5a receptor 1
C7ORF69 chromosome 7 open reading frame 69
CCDC9 coiled-coil domain containing 9
CD1C CD1c molecule
CD320 CD320 molecule
COQ6 coenzyme Q6 monooxygenase
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTSO cathepsin O
DCAF17 DDB1 and CUL4 associated factor 17
DEAF1 DEAF1 transcription factor
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ELP6 elongator acetyltransferase complex subunit 6
ENDOG endonuclease G
EXD3 exonuclease 3'-5' domain containing 3
FAM127B family with sequence similarity 127, member B
FAM86B1 family with sequence similarity 86, member B1
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FGGY FGGY carbohydrate kinase domain containing
FHL3 four and a half LIM domains 3
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GMEB1 glucocorticoid modulatory element binding protein 1
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GP6 glycoprotein VI (platelet)
GPC3 glypican 3
GRAMD1B GRAM domain containing 1B
HDAC7 histone deacetylase 7
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H2BC histone cluster 1, H2bc
HYAL3 hyaluronoglucosaminidase 3
IFI44L interferon-induced protein 44-like
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IL12RB1 interleukin 12 receptor, beta 1
INHBE inhibin, beta E
ISG15 ISG15 ubiquitin-like modifier
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCTD15 potassium channel tetramerization domain containing 15
KLF3 Kruppel-like factor 3 (basic)
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LGALS4 lectin, galactoside-binding, soluble, 4
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
MBNL3 muscleblind-like splicing regulator 3
MED22 mediator complex subunit 22
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MX1 MX dynamin-like GTPase 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOL6 nucleolar protein 6 (RNA-associated)
NOTCH1 notch 1
NPFFR1 neuropeptide FF receptor 1
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OR1G1 olfactory receptor, family 1, subfamily G, member 1
P2RY11 purinergic receptor P2Y, G-protein coupled, 11
PARP12 poly (ADP-ribose) polymerase family, member 12
PARP16 poly (ADP-ribose) polymerase family, member 16
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PRKCZ protein kinase C, zeta
PYGB phosphorylase, glycogen; brain
RAB33A RAB33A, member RAS oncogene family
RABL3 RAB, member of RAS oncogene family-like 3
RNF122 ring finger protein 122
RPL23AP32 ribosomal protein L23a pseudogene 32
SERGEF secretion regulating guanine nucleotide exchange factor
SETD1A SET domain containing 1A
SETD6 SET domain containing 6
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SIK1 salt-inducible kinase 1
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SMR3A submaxillary gland androgen regulated protein 3A
SMYD5 SMYD family member 5
SPATA1 spermatogenesis associated 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TBC1D17 TBC1 domain family, member 17
TERT telomerase reverse transcriptase
THEM6 thioesterase superfamily member 6
TICAM1 toll-like receptor adaptor molecule 1
TNS2 tensin 2
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TUBA3C tubulin, alpha 3c
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
ZNF34 zinc finger protein 34
ZNF428 zinc finger protein 428
ZNF747 zinc finger protein 747
ZNF804A zinc finger protein 804A
ZNF862 zinc finger protein 862