trichostatin A-6085 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the trichostatin A-6085 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADM adrenomedullin
AHNAK2 AHNAK nucleoprotein 2
AKAP12 A kinase (PRKA) anchor protein 12
ALDOC aldolase C, fructose-bisphosphate
ANG angiogenin, ribonuclease, RNase A family, 5
ANGPTL4 angiopoietin-like 4
ARMCX2 armadillo repeat containing, X-linked 2
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
CCDC28A coiled-coil domain containing 28A
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEP112 centrosomal protein 112kDa
CLGN calmegin
CORO1A coronin, actin binding protein, 1A
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CXADR coxsackie virus and adenovirus receptor
CXCR4 chemokine (C-X-C motif) receptor 4
CYLD cylindromatosis (turban tumor syndrome)
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DPYSL4 dihydropyrimidinase-like 4
EFNB3 ephrin-B3
ELOVL4 ELOVL fatty acid elongase 4
EPOR erythropoietin receptor
FKBP1B FK506 binding protein 1B, 12.6 kDa
FYN FYN proto-oncogene, Src family tyrosine kinase
GABARAPL1 GABA(A) receptor-associated protein like 1
GEM GTP binding protein overexpressed in skeletal muscle
GLDC glycine dehydrogenase (decarboxylating)
GLRX glutaredoxin (thioltransferase)
GPRC5B G protein-coupled receptor, class C, group 5, member B
GRK5 G protein-coupled receptor kinase 5
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HIC2 hypermethylated in cancer 2
HOXA1 homeobox A1
HYAL1 hyaluronoglucosaminidase 1
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
ITM2C integral membrane protein 2C
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KIF21B kinesin family member 21B
KLHL24 kelch-like family member 24
LIMA1 LIM domain and actin binding 1
LINC00341 long intergenic non-protein coding RNA 341
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MMD monocyte to macrophage differentiation-associated
MUC3B mucin 3B, cell surface associated
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NPC1 Niemann-Pick disease, type C1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR6A1 nuclear receptor subfamily 6, group A, member 1
NRTN neurturin
NXN nucleoredoxin
OASL 2'-5'-oligoadenylate synthetase-like
PADI3 peptidyl arginine deiminase, type III
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCLO piccolo presynaptic cytomatrix protein
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PRPH peripherin
PTRF polymerase I and transcript release factor
RAB3B RAB3B, member RAS oncogene family
RAI2 retinoic acid induced 2
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
RNASE4 ribonuclease, RNase A family, 4
RPL3L ribosomal protein L3-like
RTN2 reticulon 2
RUNDC3B RUN domain containing 3B
S100A8 S100 calcium binding protein A8
SEPP1 selenoprotein P, plasma, 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SIRT4 sirtuin 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SPTAN1 spectrin, alpha, non-erythrocytic 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STON1 stonin 1
STXBP1 syntaxin binding protein 1
SYT11 synaptotagmin XI
TBXA2R thromboxane A2 receptor
THEMIS2 thymocyte selection associated family member 2
TMEM45A transmembrane protein 45A
TRIM2 tripartite motif containing 2
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
WDR19 WD repeat domain 19
ZBTB18 zinc finger and BTB domain containing 18
ZCCHC24 zinc finger, CCHC domain containing 24
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF204P zinc finger protein 204, pseudogene

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADGRA3 adhesion G protein-coupled receptor A3
ADNP activity-dependent neuroprotector homeobox
AKAP8 A kinase (PRKA) anchor protein 8
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ASPHD1 aspartate beta-hydroxylase domain containing 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
AXIN1 axin 1
BANP BTG3 associated nuclear protein
BATF basic leucine zipper transcription factor, ATF-like
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C9ORF91 chromosome 9 open reading frame 91
CALHM2 calcium homeostasis modulator 2
CASD1 CAS1 domain containing 1
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCDC94 coiled-coil domain containing 94
CCND1 cyclin D1
CCNL2 cyclin L2
CCNO cyclin O
CHKB choline kinase beta
COA7 cytochrome c oxidase assembly factor 7 (putative)
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DEAF1 DEAF1 transcription factor
DKK1 dickkopf WNT signaling pathway inhibitor 1
EXOSC10 exosome component 10
FAM57A family with sequence similarity 57, member A
FJX1 four jointed box 1 (Drosophila)
FOSL1 FOS-like antigen 1
FOXA1 forkhead box A1
GABPB1 GA binding protein transcription factor, beta subunit 1
GATA3 GATA binding protein 3
GMEB1 glucocorticoid modulatory element binding protein 1
GMEB2 glucocorticoid modulatory element binding protein 2
GPR87 G protein-coupled receptor 87
GTF2I general transcription factor IIi
H2AFY2 H2A histone family, member Y2
HIRIP3 HIRA interacting protein 3
IL15RA interleukin 15 receptor, alpha
IMPACT impact RWD domain protein
INHBB inhibin, beta B
IRAK4 interleukin-1 receptor-associated kinase 4
IRS1 insulin receptor substrate 1
IRX5 iroquois homeobox 5
ITPKB inositol-trisphosphate 3-kinase B
KEAP1 kelch-like ECH-associated protein 1
KIAA0125 KIAA0125
LMNB1 lamin B1
LUC7L2 LUC7-like 2 (S. cerevisiae)
LY6G5C lymphocyte antigen 6 complex, locus G5C
MBTPS2 membrane-bound transcription factor peptidase, site 2
MEPCE methylphosphate capping enzyme
METTL1 methyltransferase like 1
MPPED2 metallophosphoesterase domain containing 2
MSL1 male-specific lethal 1 homolog (Drosophila)
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NRIP1 nuclear receptor interacting protein 1
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
NUAK1 NUAK family, SNF1-like kinase, 1
PDGFA platelet-derived growth factor alpha polypeptide
PHLDA3 pleckstrin homology-like domain, family A, member 3
POGK pogo transposable element with KRAB domain
PRR15L proline rich 15-like
QTRT1 queuine tRNA-ribosyltransferase 1
RANGRF RAN guanine nucleotide release factor
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM23 RNA binding motif protein 23
SETD1B SET domain containing 1B
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMG9 SMG9 nonsense mediated mRNA decay factor
SPHK1 sphingosine kinase 1
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SRSF4 serine/arginine-rich splicing factor 4
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STC2 stanniocalcin 2
TCERG1 transcription elongation regulator 1
TRIB3 tribbles pseudokinase 3
TRIM16 tripartite motif containing 16
TRPS1 trichorhinophalangeal syndrome I
TSKU tsukushi, small leucine rich proteoglycan
UBL4A ubiquitin-like 4A
UBXN8 UBX domain protein 8
WDR4 WD repeat domain 4
WDR43 WD repeat domain 43
XBP1 X-box binding protein 1
YAP1 Yes-associated protein 1
ZBED1 zinc finger, BED-type containing 1
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF33B zinc finger protein 33B
ZNF573 zinc finger protein 573
ZNF692 zinc finger protein 692
ZNF787 zinc finger protein 787
ZNHIT2 zinc finger, HIT-type containing 2
ZZZ3 zinc finger, ZZ-type containing 3