trichostatin A-6064 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the trichostatin A-6064 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADM adrenomedullin
AHNAK2 AHNAK nucleoprotein 2
AIM1L absent in melanoma 1-like
AKAP12 A kinase (PRKA) anchor protein 12
ANG angiogenin, ribonuclease, RNase A family, 5
ARMCX2 armadillo repeat containing, X-linked 2
CA5B carbonic anhydrase VB, mitochondrial
CASC1 cancer susceptibility candidate 1
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEP112 centrosomal protein 112kDa
CLGN calmegin
CORO1A coronin, actin binding protein, 1A
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSRP2 cysteine and glycine-rich protein 2
CXADR coxsackie virus and adenovirus receptor
CYLD cylindromatosis (turban tumor syndrome)
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DFNB31 deafness, autosomal recessive 31
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DPYSL4 dihydropyrimidinase-like 4
EFNA3 ephrin-A3
EFNB3 ephrin-B3
ELOVL4 ELOVL fatty acid elongase 4
ERO1LB ERO1-like beta (S. cerevisiae)
FAM46C family with sequence similarity 46, member C
FKBP1B FK506 binding protein 1B, 12.6 kDa
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GABARAPL1 GABA(A) receptor-associated protein like 1
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GCHFR GTP cyclohydrolase I feedback regulator
GEM GTP binding protein overexpressed in skeletal muscle
GLDC glycine dehydrogenase (decarboxylating)
GLRX glutaredoxin (thioltransferase)
GRK5 G protein-coupled receptor kinase 5
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HOXA1 homeobox A1
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
KIF21B kinesin family member 21B
KLHL24 kelch-like family member 24
KLHL25 kelch-like family member 25
LIMA1 LIM domain and actin binding 1
LINC00341 long intergenic non-protein coding RNA 341
LYST lysosomal trafficking regulator
MAP1B microtubule-associated protein 1B
MARK4 MAP/microtubule affinity-regulating kinase 4
MMD monocyte to macrophage differentiation-associated
MUC3B mucin 3B, cell surface associated
NAP1L3 nucleosome assembly protein 1-like 3
NME5 NME/NM23 family member 5
NPC1 Niemann-Pick disease, type C1
NR6A1 nuclear receptor subfamily 6, group A, member 1
NXN nucleoredoxin
PADI3 peptidyl arginine deiminase, type III
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PML promyelocytic leukemia
PRPH peripherin
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTCH1 patched 1
RAI2 retinoic acid induced 2
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
RNASE4 ribonuclease, RNase A family, 4
RND1 Rho family GTPase 1
RPL3L ribosomal protein L3-like
RTN2 reticulon 2
RUNDC3B RUN domain containing 3B
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPP1 selenoprotein P, plasma, 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SFXN3 sideroflexin 3
SH3GL3 SH3-domain GRB2-like 3
SIRT4 sirtuin 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC30A3 solute carrier family 30 (zinc transporter), member 3
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STON1 stonin 1
STXBP1 syntaxin binding protein 1
SYT11 synaptotagmin XI
TBXA2R thromboxane A2 receptor
TIMP3 TIMP metallopeptidase inhibitor 3
TMOD2 tropomodulin 2 (neuronal)
TNIK TRAF2 and NCK interacting kinase
TRAFD1 TRAF-type zinc finger domain containing 1
TRIM2 tripartite motif containing 2
WDR19 WD repeat domain 19
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZBTB18 zinc finger and BTB domain containing 18
ZCCHC24 zinc finger, CCHC domain containing 24
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF10 zinc finger protein 10
ZNF204P zinc finger protein 204, pseudogene

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADGRA3 adhesion G protein-coupled receptor A3
ADNP activity-dependent neuroprotector homeobox
AEN apoptosis enhancing nuclease
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C9ORF91 chromosome 9 open reading frame 91
CASD1 CAS1 domain containing 1
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCDC94 coiled-coil domain containing 94
CCND1 cyclin D1
CDK3 cyclin-dependent kinase 3
CISH cytokine inducible SH2-containing protein
CLCF1 cardiotrophin-like cytokine factor 1
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
DGAT1 diacylglycerol O-acyltransferase 1
DIO2 deiodinase, iodothyronine, type II
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNM3 dynamin 3
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EGR3 early growth response 3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM57A family with sequence similarity 57, member A
FBXO22 F-box protein 22
FJX1 four jointed box 1 (Drosophila)
FOXC1 forkhead box C1
FOXI1 forkhead box I1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GATA3 GATA binding protein 3
GMEB1 glucocorticoid modulatory element binding protein 1
GPR87 G protein-coupled receptor 87
INHBB inhibin, beta B
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRS1 insulin receptor substrate 1
IRX5 iroquois homeobox 5
ITPKB inositol-trisphosphate 3-kinase B
KEAP1 kelch-like ECH-associated protein 1
KIAA0125 KIAA0125
KLF3 Kruppel-like factor 3 (basic)
LMNB1 lamin B1
LRRC61 leucine rich repeat containing 61
LY6D lymphocyte antigen 6 complex, locus D
LY6G5C lymphocyte antigen 6 complex, locus G5C
MCM9 minichromosome maintenance complex component 9
MEPCE methylphosphate capping enzyme
METTL1 methyltransferase like 1
METTL8 methyltransferase like 8
MSI1 musashi RNA-binding protein 1
MSL1 male-specific lethal 1 homolog (Drosophila)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NIPAL2 NIPA-like domain containing 2
NOD1 nucleotide-binding oligomerization domain containing 1
NRIP1 nuclear receptor interacting protein 1
NUAK1 NUAK family, SNF1-like kinase, 1
PCDHA9 protocadherin alpha 9
PEX26 peroxisomal biogenesis factor 26
PHLDA3 pleckstrin homology-like domain, family A, member 3
PLK1 polo-like kinase 1
POGK pogo transposable element with KRAB domain
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PQLC2 PQ loop repeat containing 2
PRNP prion protein
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM23 RNA binding motif protein 23
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SBNO2 strawberry notch homolog 2 (Drosophila)
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SFMBT1 Scm-like with four mbt domains 1
SH2D4A SH2 domain containing 4A
SLC35F2 solute carrier family 35, member F2
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SNHG20 small nucleolar RNA host gene 20
SOX12 SRY (sex determining region Y)-box 12
SREK1 splicing regulatory glutamine/lysine-rich protein 1
STC2 stanniocalcin 2
TDRD3 tudor domain containing 3
TOE1 target of EGR1, member 1 (nuclear)
TRIB3 tribbles pseudokinase 3
TRIM16 tripartite motif containing 16
TRIM8 tripartite motif containing 8
TRPS1 trichorhinophalangeal syndrome I
TSKU tsukushi, small leucine rich proteoglycan
UBL4A ubiquitin-like 4A
UBTF upstream binding transcription factor, RNA polymerase I
VPS9D1 VPS9 domain containing 1
WDR74 WD repeat domain 74
XBP1 X-box binding protein 1
YY2 YY2 transcription factor
ZBED1 zinc finger, BED-type containing 1
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF33B zinc finger protein 33B
ZNF532 zinc finger protein 532
ZNF692 zinc finger protein 692
ZNF787 zinc finger protein 787