trichostatin A-5940 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

199 genes differentially expressed following the trichostatin A-5940 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
AHR aryl hydrocarbon receptor
ANGPTL4 angiopoietin-like 4
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AQP3 aquaporin 3 (Gill blood group)
ARC activity-regulated cytoskeleton-associated protein
AREG amphiregulin
ARG2 arginase 2
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASMTL acetylserotonin O-methyltransferase-like
AVPI1 arginine vasopressin-induced 1
BAIAP2 BAI1-associated protein 2
BAMBI BMP and activin membrane-bound inhibitor
BEX1 brain expressed, X-linked 1
BMP4 bone morphogenetic protein 4
BMP6 bone morphogenetic protein 6
C18ORF8 chromosome 18 open reading frame 8
CA5B carbonic anhydrase VB, mitochondrial
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CORO1A coronin, actin binding protein, 1A
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2
CTGF connective tissue growth factor
CXCR4 chemokine (C-X-C motif) receptor 4
CYR61 cysteine-rich, angiogenic inducer, 61
DENND3 DENN/MADD domain containing 3
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DPYSL4 dihydropyrimidinase-like 4
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
EFNA4 ephrin-A4
EGR2 early growth response 2
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ELOVL4 ELOVL fatty acid elongase 4
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FABP4 fatty acid binding protein 4, adipocyte
FAM69A family with sequence similarity 69, member A
GLCE glucuronic acid epimerase
GLS glutaminase
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IL11 interleukin 11
INSIG1 insulin induced gene 1
IRF6 interferon regulatory factor 6
IRS2 insulin receptor substrate 2
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIF5C kinesin family member 5C
KRT86 keratin 86, type II
LMCD1 LIM and cysteine-rich domains 1
LOC157562 uncharacterized LOC157562
LPPR4 lipid phosphate phosphatase-related protein type 4
MAP2K3 mitogen-activated protein kinase kinase 3
MAPT microtubule-associated protein tau
MERTK MER proto-oncogene, tyrosine kinase
MLF1 myeloid leukemia factor 1
MMP1 matrix metallopeptidase 1
NME5 NME/NM23 family member 5
NMT2 N-myristoyltransferase 2
NR4A1 nuclear receptor subfamily 4, group A, member 1
PCDH9 protocadherin 9
PDE4DIP phosphodiesterase 4D interacting protein
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PKP2 plakophilin 2
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRPH peripherin
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAI2 retinoic acid induced 2
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS4 regulator of G-protein signaling 4
RHOB ras homolog family member B
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SAT1 spermidine/spermine N1-acetyltransferase 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STC1 stanniocalcin 1
STK17B serine/threonine kinase 17b
STON1 stonin 1
SYT1 synaptotagmin I
SYT11 synaptotagmin XI
TAOK3 TAO kinase 3
TBC1D16 TBC1 domain family, member 16
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRAFD1 TRAF-type zinc finger domain containing 1
TRIM62 tripartite motif containing 62
TUBB2B tubulin, beta 2B class IIb
TUFT1 tuftelin 1
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
VWA1 von Willebrand factor A domain containing 1
ZMIZ2 zinc finger, MIZ-type containing 2

decreased expression

Symbol Name
ADNP activity-dependent neuroprotector homeobox
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARHGAP11A Rho GTPase activating protein 11A
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
AXIN1 axin 1
BCAR3 breast cancer anti-estrogen resistance 3
BCL7A B-cell CLL/lymphoma 7A
BNC2 basonuclin 2
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CASD1 CAS1 domain containing 1
CBR3 carbonyl reductase 3
CCDC94 coiled-coil domain containing 94
CLCF1 cardiotrophin-like cytokine factor 1
COG7 component of oligomeric golgi complex 7
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CUL1 cullin 1
CYTH2 cytohesin 2
DEPDC1 DEP domain containing 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DUSP4 dual specificity phosphatase 4
ELP3 elongator acetyltransferase complex subunit 3
ESM1 endothelial cell-specific molecule 1
FJX1 four jointed box 1 (Drosophila)
FOSL1 FOS-like antigen 1
FOXA1 forkhead box A1
FST follistatin
GABPB1 GA binding protein transcription factor, beta subunit 1
GBX2 gastrulation brain homeobox 2
GMEB1 glucocorticoid modulatory element binding protein 1
GPR87 G protein-coupled receptor 87
GRPR gastrin-releasing peptide receptor
GTF2IRD1 GTF2I repeat domain containing 1
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HAS2 hyaluronan synthase 2
HMGA2 high mobility group AT-hook 2
IL4R interleukin 4 receptor
IL7R interleukin 7 receptor
INHBB inhibin, beta B
KAT6B K(lysine) acetyltransferase 6B
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCTD15 potassium channel tetramerization domain containing 15
KEAP1 kelch-like ECH-associated protein 1
KIRREL kin of IRRE like (Drosophila)
LIF leukemia inhibitory factor
LPAR1 lysophosphatidic acid receptor 1
LRRC41 leucine rich repeat containing 41
LRRC61 leucine rich repeat containing 61
MCM9 minichromosome maintenance complex component 9
MEPCE methylphosphate capping enzyme
MPDU1 mannose-P-dolichol utilization defect 1
MX1 MX dynamin-like GTPase 1
NME6 NME/NM23 nucleoside diphosphate kinase 6
NRIP1 nuclear receptor interacting protein 1
NTSR1 neurotensin receptor 1 (high affinity)
PAGR1 PAXIP1 associated glutamate-rich protein 1
PAX6 paired box 6
PEF1 penta-EF-hand domain containing 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLK1 polo-like kinase 1
POGK pogo transposable element with KRAB domain
PPAP2B phosphatidic acid phosphatase type 2B
PPCDC phosphopantothenoylcysteine decarboxylase
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RBM4B RNA binding motif protein 4B
RIN2 Ras and Rab interactor 2
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SETD1B SET domain containing 1B
SFMBT1 Scm-like with four mbt domains 1
SIM2 single-minded family bHLH transcription factor 2
SLC35F2 solute carrier family 35, member F2
SMG9 SMG9 nonsense mediated mRNA decay factor
SMYD5 SMYD family member 5
SNX5 sorting nexin 5
SOX12 SRY (sex determining region Y)-box 12
SRSF4 serine/arginine-rich splicing factor 4
TCEAL1 transcription elongation factor A (SII)-like 1
TEP1 telomerase-associated protein 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TMC7 transmembrane channel-like 7
TMEM53 transmembrane protein 53
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TOE1 target of EGR1, member 1 (nuclear)
TRIB3 tribbles pseudokinase 3
TSKU tsukushi, small leucine rich proteoglycan
USP21 ubiquitin specific peptidase 21
VEGFC vascular endothelial growth factor C
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBED1 zinc finger, BED-type containing 1
ZC3H4 zinc finger CCCH-type containing 4
ZMYM3 zinc finger, MYM-type 3
ZNF239 zinc finger protein 239
ZNF32 zinc finger protein 32
ZNF532 zinc finger protein 532
ZNF787 zinc finger protein 787
ZSCAN31 zinc finger and SCAN domain containing 31