trichostatin A-5935 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the trichostatin A-5935 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACSBG1 acyl-CoA synthetase bubblegum family member 1
AHNAK2 AHNAK nucleoprotein 2
BAIAP3 BAI1-associated protein 3
CASC1 cancer susceptibility candidate 1
CCNA1 cyclin A1
CDH15 cadherin 15, type 1, M-cadherin (myotubule)
CDH18 cadherin 18, type 2
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLGN calmegin
CLIP2 CAP-GLY domain containing linker protein 2
CLTCL1 clathrin, heavy chain-like 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CXADR coxsackie virus and adenovirus receptor
CYLD cylindromatosis (turban tumor syndrome)
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DENND3 DENN/MADD domain containing 3
DHRS2 dehydrogenase/reductase (SDR family) member 2
EFNA3 ephrin-A3
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPOR erythropoietin receptor
FAM134B family with sequence similarity 134, member B
FAM13A family with sequence similarity 13, member A
FAM46C family with sequence similarity 46, member C
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GEM GTP binding protein overexpressed in skeletal muscle
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GLDC glycine dehydrogenase (decarboxylating)
GLRX glutaredoxin (thioltransferase)
GMPR guanosine monophosphate reductase
GOSR2 golgi SNAP receptor complex member 2
GPR20 G protein-coupled receptor 20
GTF2B general transcription factor IIB
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HYAL1 hyaluronoglucosaminidase 1
KIAA1462 KIAA1462
KIF21B kinesin family member 21B
LIMA1 LIM domain and actin binding 1
LMCD1 LIM and cysteine-rich domains 1
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAP1A microtubule-associated protein 1A
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MAPRE2 microtubule-associated protein, RP/EB family, member 2
NAP1L3 nucleosome assembly protein 1-like 3
NPC1 Niemann-Pick disease, type C1
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRTN neurturin
NXN nucleoredoxin
OASL 2'-5'-oligoadenylate synthetase-like
PADI3 peptidyl arginine deiminase, type III
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCLO piccolo presynaptic cytomatrix protein
PDE4DIP phosphodiesterase 4D interacting protein
PEG10 paternally expressed 10
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PKNOX2 PBX/knotted 1 homeobox 2
PLEKHO2 pleckstrin homology domain containing, family O member 2
PRPH peripherin
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
RAI2 retinoic acid induced 2
RGCC regulator of cell cycle
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
RND1 Rho family GTPase 1
RPL3L ribosomal protein L3-like
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RUNDC3B RUN domain containing 3B
SEPP1 selenoprotein P, plasma, 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SIRT4 sirtuin 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SNAI2 snail family zinc finger 2
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
SYT11 synaptotagmin XI
TDRKH tudor and KH domain containing
TIMP3 TIMP metallopeptidase inhibitor 3
TMCC2 transmembrane and coiled-coil domain family 2
TPMT thiopurine S-methyltransferase
TTLL7 tubulin tyrosine ligase-like family member 7
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VWA5A von Willebrand factor A domain containing 5A
WDR47 WD repeat domain 47
YPEL1 yippee-like 1 (Drosophila)
ZCCHC24 zinc finger, CCHC domain containing 24
ZDHHC11 zinc finger, DHHC-type containing 11
ZEB1 zinc finger E-box binding homeobox 1
ZHX3 zinc fingers and homeoboxes 3
ZNF10 zinc finger protein 10
ZNF204P zinc finger protein 204, pseudogene
ZNF230 zinc finger protein 230

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ACVR2B activin A receptor, type IIB
ADNP activity-dependent neuroprotector homeobox
AMIGO2 adhesion molecule with Ig-like domain 2
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARTN artemin
BEGAIN brain-enriched guanylate kinase-associated
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C9ORF9 chromosome 9 open reading frame 9
CALHM2 calcium homeostasis modulator 2
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CBR3 carbonyl reductase 3
CCDC94 coiled-coil domain containing 94
CCND1 cyclin D1
CHST10 carbohydrate sulfotransferase 10
COIL coilin
CRMP1 collapsin response mediator protein 1
CTCF CCCTC-binding factor (zinc finger protein)
DEPDC1 DEP domain containing 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAAF2 dynein, axonemal, assembly factor 2
DSCAM Down syndrome cell adhesion molecule
EFNA1 ephrin-A1
EGR3 early growth response 3
FAM57A family with sequence similarity 57, member A
FGD1 FYVE, RhoGEF and PH domain containing 1
FJX1 four jointed box 1 (Drosophila)
FOXA1 forkhead box A1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GABPB1 GA binding protein transcription factor, beta subunit 1
GATA4 GATA binding protein 4
GPR87 G protein-coupled receptor 87
GPRC5C G protein-coupled receptor, class C, group 5, member C
GTF2IRD1 GTF2I repeat domain containing 1
HDAC7 histone deacetylase 7
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HOXC11 homeobox C11
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IL15RA interleukin 15 receptor, alpha
INHBB inhibin, beta B
IRF2 interferon regulatory factor 2
IRS1 insulin receptor substrate 1
IRX5 iroquois homeobox 5
ITPKB inositol-trisphosphate 3-kinase B
KCTD15 potassium channel tetramerization domain containing 15
KDM8 lysine (K)-specific demethylase 8
KIAA0125 KIAA0125
LMNB1 lamin B1
LY6G5C lymphocyte antigen 6 complex, locus G5C
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MEPCE methylphosphate capping enzyme
METTL4 methyltransferase like 4
MSL1 male-specific lethal 1 homolog (Drosophila)
MYC v-myc avian myelocytomatosis viral oncogene homolog
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NOD1 nucleotide-binding oligomerization domain containing 1
NPY1R neuropeptide Y receptor Y1
NRIP1 nuclear receptor interacting protein 1
NUAK1 NUAK family, SNF1-like kinase, 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PDGFA platelet-derived growth factor alpha polypeptide
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PHEX phosphate regulating endopeptidase homolog, X-linked
PHLDA3 pleckstrin homology-like domain, family A, member 3
POGK pogo transposable element with KRAB domain
PRR15L proline rich 15-like
PTPN9 protein tyrosine phosphatase, non-receptor type 9
R3HCC1L R3H domain and coiled-coil containing 1-like
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM23 RNA binding motif protein 23
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SETD1B SET domain containing 1B
SFMBT1 Scm-like with four mbt domains 1
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMAD7 SMAD family member 7
SNHG3 small nucleolar RNA host gene 3
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SRSF4 serine/arginine-rich splicing factor 4
STC2 stanniocalcin 2
TGIF1 TGFB-induced factor homeobox 1
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TRIB1 tribbles pseudokinase 1
TRIB3 tribbles pseudokinase 3
TRIM16 tripartite motif containing 16
TRIM8 tripartite motif containing 8
TSKU tsukushi, small leucine rich proteoglycan
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
XBP1 X-box binding protein 1
ZBTB1 zinc finger and BTB domain containing 1
ZC3H4 zinc finger CCCH-type containing 4
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1
ZNF573 zinc finger protein 573
ZNF668 zinc finger protein 668
ZNF692 zinc finger protein 692
ZNF787 zinc finger protein 787
ZNHIT2 zinc finger, HIT-type containing 2