trichostatin A-5908 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the trichostatin A-5908 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACOT7 acyl-CoA thioesterase 7
AGTR1 angiotensin II receptor, type 1
AHR aryl hydrocarbon receptor
AMDHD2 amidohydrolase domain containing 2
ANGPTL4 angiopoietin-like 4
AQP3 aquaporin 3 (Gill blood group)
ARG2 arginase 2
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASMTL acetylserotonin O-methyltransferase-like
AVPI1 arginine vasopressin-induced 1
BAIAP2 BAI1-associated protein 2
BAMBI BMP and activin membrane-bound inhibitor
BCL6 B-cell CLL/lymphoma 6
C1QL1 complement component 1, q subcomponent-like 1
C5ORF45 chromosome 5 open reading frame 45
CA5B carbonic anhydrase VB, mitochondrial
CD70 CD70 molecule
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CORO1A coronin, actin binding protein, 1A
CPM carboxypeptidase M
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTGF connective tissue growth factor
CTH cystathionine gamma-lyase
CXCR4 chemokine (C-X-C motif) receptor 4
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DENND3 DENN/MADD domain containing 3
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
EFNA3 ephrin-A3
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ELOVL4 ELOVL fatty acid elongase 4
EPPK1 epiplakin 1
FABP4 fatty acid binding protein 4, adipocyte
FAM134B family with sequence similarity 134, member B
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
GCDH glutaryl-CoA dehydrogenase
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GLS glutaminase
GMPR guanosine monophosphate reductase
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IL11 interleukin 11
INSIG1 insulin induced gene 1
IRF6 interferon regulatory factor 6
JUNB jun B proto-oncogene
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIF5C kinesin family member 5C
LIPE lipase, hormone-sensitive
LMCD1 LIM and cysteine-rich domains 1
LPPR4 lipid phosphate phosphatase-related protein type 4
LTB4R leukotriene B4 receptor
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MAPT microtubule-associated protein tau
MERTK MER proto-oncogene, tyrosine kinase
MMP1 matrix metallopeptidase 1
MOCS3 molybdenum cofactor synthesis 3
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEU1 sialidase 1 (lysosomal sialidase)
NPC1 Niemann-Pick disease, type C1
OASL 2'-5'-oligoadenylate synthetase-like
PCDH17 protocadherin 17
PDE4DIP phosphodiesterase 4D interacting protein
PELI1 pellino E3 ubiquitin protein ligase 1
PKP2 plakophilin 2
PLXNA3 plexin A3
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RGCC regulator of cell cycle
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS17 regulator of G-protein signaling 17
RGS4 regulator of G-protein signaling 4
RND1 Rho family GTPase 1
RNF24 ring finger protein 24
SAT1 spermidine/spermine N1-acetyltransferase 1
SELPLG selectin P ligand
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL2 SH3-domain GRB2-like 2
SH3GL3 SH3-domain GRB2-like 3
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SNAP23 synaptosomal-associated protein, 23kDa
SORBS1 sorbin and SH3 domain containing 1
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
STARD5 StAR-related lipid transfer (START) domain containing 5
STC1 stanniocalcin 1
SYT1 synaptotagmin I
SYT11 synaptotagmin XI
TAOK3 TAO kinase 3
THEMIS2 thymocyte selection associated family member 2
TJP3 tight junction protein 3
TRAIP TRAF interacting protein
TUBB2B tubulin, beta 2B class IIb
TUFT1 tuftelin 1
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)

decreased expression

Symbol Name
ADGRG6 adhesion G protein-coupled receptor G6
ADNP activity-dependent neuroprotector homeobox
ARSJ arylsulfatase family, member J
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BCAR3 breast cancer anti-estrogen resistance 3
C19ORF40 chromosome 19 open reading frame 40
C19ORF54 chromosome 19 open reading frame 54
C7ORF49 chromosome 7 open reading frame 49
C9ORF40 chromosome 9 open reading frame 40
CASD1 CAS1 domain containing 1
CBR3 carbonyl reductase 3
CCNJ cyclin J
CDC7 cell division cycle 7
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CLCF1 cardiotrophin-like cytokine factor 1
CTCF CCCTC-binding factor (zinc finger protein)
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CUL1 cullin 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DEPDC1 DEP domain containing 1
FJX1 four jointed box 1 (Drosophila)
FOSL1 FOS-like antigen 1
FOXA1 forkhead box A1
FOXC1 forkhead box C1
FRS3 fibroblast growth factor receptor substrate 3
FST follistatin
GABPB1 GA binding protein transcription factor, beta subunit 1
GPR87 G protein-coupled receptor 87
GPRIN2 G protein regulated inducer of neurite outgrowth 2
H2AFY2 H2A histone family, member Y2
HAS2 hyaluronan synthase 2
HDAC7 histone deacetylase 7
HIST1H4E histone cluster 1, H4e
HMGA2 high mobility group AT-hook 2
HOXA2 homeobox A2
HOXA4 homeobox A4
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
KAT6B K(lysine) acetyltransferase 6B
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KCTD17 potassium channel tetramerization domain containing 17
KDM8 lysine (K)-specific demethylase 8
KEAP1 kelch-like ECH-associated protein 1
KIAA1107 KIAA1107
KIF14 kinesin family member 14
KIRREL kin of IRRE like (Drosophila)
LIF leukemia inhibitory factor
LMNB1 lamin B1
LPAR1 lysophosphatidic acid receptor 1
LUC7L2 LUC7-like 2 (S. cerevisiae)
LY6G5C lymphocyte antigen 6 complex, locus G5C
MEPCE methylphosphate capping enzyme
MRPL44 mitochondrial ribosomal protein L44
MTRF1 mitochondrial translational release factor 1
NDP Norrie disease (pseudoglioma)
NHEJ1 nonhomologous end-joining factor 1
NMI N-myc (and STAT) interactor
NRIP1 nuclear receptor interacting protein 1
NSD1 nuclear receptor binding SET domain protein 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PALMD palmdelphin
PAN2 PAN2 poly(A) specific ribonuclease subunit
PPAP2B phosphatidic acid phosphatase type 2B
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RBM4B RNA binding motif protein 4B
RIN2 Ras and Rab interactor 2
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SETD1B SET domain containing 1B
SFMBT1 Scm-like with four mbt domains 1
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SIM2 single-minded family bHLH transcription factor 2
SLC12A8 solute carrier family 12, member 8
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SMAGP small cell adhesion glycoprotein
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SOGA1 suppressor of glucose, autophagy associated 1
SRSF4 serine/arginine-rich splicing factor 4
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TMC5 transmembrane channel-like 5
TMEM121 transmembrane protein 121
TRIB3 tribbles pseudokinase 3
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
UBTF upstream binding transcription factor, RNA polymerase I
VEGFC vascular endothelial growth factor C
VN1R1 vomeronasal 1 receptor 1
ZBED1 zinc finger, BED-type containing 1
ZBTB1 zinc finger and BTB domain containing 1
ZC3H4 zinc finger CCCH-type containing 4
ZNF165 zinc finger protein 165
ZNF215 zinc finger protein 215
ZNF227 zinc finger protein 227
ZNF33B zinc finger protein 33B
ZNF446 zinc finger protein 446
ZNF76 zinc finger protein 76
ZSCAN31 zinc finger and SCAN domain containing 31