trichostatin A-5903 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the trichostatin A-5903 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
AHNAK2 AHNAK nucleoprotein 2
AKAP12 A kinase (PRKA) anchor protein 12
APAF1 apoptotic peptidase activating factor 1
ARMCX2 armadillo repeat containing, X-linked 2
BAIAP2 BAI1-associated protein 2
C2ORF44 chromosome 2 open reading frame 44
CA5B carbonic anhydrase VB, mitochondrial
CASC1 cancer susceptibility candidate 1
CATSPERB catsper channel auxiliary subunit beta
CCNA1 cyclin A1
CDH15 cadherin 15, type 1, M-cadherin (myotubule)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEP112 centrosomal protein 112kDa
CLGN calmegin
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CXADR coxsackie virus and adenovirus receptor
CXCR4 chemokine (C-X-C motif) receptor 4
CXORF57 chromosome X open reading frame 57
CYLD cylindromatosis (turban tumor syndrome)
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DENND3 DENN/MADD domain containing 3
DFNB31 deafness, autosomal recessive 31
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DPF1 D4, zinc and double PHD fingers family 1
DPYSL4 dihydropyrimidinase-like 4
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FAM134B family with sequence similarity 134, member B
FAM13A family with sequence similarity 13, member A
FAM46C family with sequence similarity 46, member C
FAM49A family with sequence similarity 49, member A
FKBP1B FK506 binding protein 1B, 12.6 kDa
FOS FBJ murine osteosarcoma viral oncogene homolog
GEM GTP binding protein overexpressed in skeletal muscle
GLDC glycine dehydrogenase (decarboxylating)
GLRX glutaredoxin (thioltransferase)
GRK5 G protein-coupled receptor kinase 5
GSDMB gasdermin B
HBEGF heparin-binding EGF-like growth factor
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HOXA1 homeobox A1
IL21R interleukin 21 receptor
KIF21B kinesin family member 21B
KLF2 Kruppel-like factor 2
LIMA1 LIM domain and actin binding 1
LINC00312 long intergenic non-protein coding RNA 312
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MAPRE2 microtubule-associated protein, RP/EB family, member 2
NAP1L3 nucleosome assembly protein 1-like 3
NPC1 Niemann-Pick disease, type C1
NSUN6 NOP2/Sun domain family, member 6
NXN nucleoredoxin
PADI3 peptidyl arginine deiminase, type III
PDE4DIP phosphodiesterase 4D interacting protein
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PRPH peripherin
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
RAI2 retinoic acid induced 2
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
RNASE4 ribonuclease, RNase A family, 4
RPL3L ribosomal protein L3-like
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RUNDC3B RUN domain containing 3B
SAT1 spermidine/spermine N1-acetyltransferase 1
SEC14L5 SEC14-like 5 (S. cerevisiae)
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SENP5 SUMO1/sentrin specific peptidase 5
SEPP1 selenoprotein P, plasma, 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SIRT4 sirtuin 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SNAI1 snail family zinc finger 1
SNAI2 snail family zinc finger 2
SORBS1 sorbin and SH3 domain containing 1
STX7 syntaxin 7
SYT11 synaptotagmin XI
TDRKH tudor and KH domain containing
THEMIS2 thymocyte selection associated family member 2
TIMP3 TIMP metallopeptidase inhibitor 3
TUFT1 tuftelin 1
ULBP2 UL16 binding protein 2
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VWA5A von Willebrand factor A domain containing 5A
WAS Wiskott-Aldrich syndrome
WDR19 WD repeat domain 19
WDR47 WD repeat domain 47
XYLT1 xylosyltransferase I
ZCCHC24 zinc finger, CCHC domain containing 24

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADNP activity-dependent neuroprotector homeobox
ADRA2C adrenoceptor alpha 2C
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
B9D2 B9 protein domain 2
BATF basic leucine zipper transcription factor, ATF-like
BCAR3 breast cancer anti-estrogen resistance 3
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C14ORF93 chromosome 14 open reading frame 93
C9ORF91 chromosome 9 open reading frame 91
CALHM2 calcium homeostasis modulator 2
CAPN15 calpain 15
CASD1 CAS1 domain containing 1
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCDC94 coiled-coil domain containing 94
CCND1 cyclin D1
CD3D CD3d molecule, delta (CD3-TCR complex)
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DSCAM Down syndrome cell adhesion molecule
DUSP4 dual specificity phosphatase 4
EFNA1 ephrin-A1
EGR3 early growth response 3
ELP6 elongator acetyltransferase complex subunit 6
FJX1 four jointed box 1 (Drosophila)
GMEB1 glucocorticoid modulatory element binding protein 1
GPATCH4 G patch domain containing 4
GPR87 G protein-coupled receptor 87
GPRC5C G protein-coupled receptor, class C, group 5, member C
GTF2IRD1 GTF2I repeat domain containing 1
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HOXC11 homeobox C11
IL15RA interleukin 15 receptor, alpha
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
IRX5 iroquois homeobox 5
ITPKB inositol-trisphosphate 3-kinase B
KCTD15 potassium channel tetramerization domain containing 15
KEAP1 kelch-like ECH-associated protein 1
KLF3 Kruppel-like factor 3 (basic)
LY6G5C lymphocyte antigen 6 complex, locus G5C
MEPCE methylphosphate capping enzyme
MEX3C mex-3 RNA binding family member C
MSL1 male-specific lethal 1 homolog (Drosophila)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NOD1 nucleotide-binding oligomerization domain containing 1
NRIP1 nuclear receptor interacting protein 1
NUAK1 NUAK family, SNF1-like kinase, 1
OVOL1 ovo-like zinc finger 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PNMAL1 paraneoplastic Ma antigen family-like 1
POGK pogo transposable element with KRAB domain
POU5F1B POU class 5 homeobox 1B
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRR15L proline rich 15-like
PRR4 proline rich 4 (lacrimal)
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PUS1 pseudouridylate synthase 1
RAB40A RAB40A, member RAS oncogene family
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM23 RNA binding motif protein 23
RGS19 regulator of G-protein signaling 19
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SENP6 SUMO1/sentrin specific peptidase 6
SETD1B SET domain containing 1B
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SH2D4A SH2 domain containing 4A
SMAD7 SMAD family member 7
SMG9 SMG9 nonsense mediated mRNA decay factor
SPINK5 serine peptidase inhibitor, Kazal type 5
SRSF4 serine/arginine-rich splicing factor 4
STC2 stanniocalcin 2
TAOK1 TAO kinase 1
TGIF1 TGFB-induced factor homeobox 1
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TRIB3 tribbles pseudokinase 3
TSKU tsukushi, small leucine rich proteoglycan
VPS9D1 VPS9 domain containing 1
XBP1 X-box binding protein 1
XDH xanthine dehydrogenase
ZBED1 zinc finger, BED-type containing 1
ZC3H4 zinc finger CCCH-type containing 4
ZFP69B ZFP69 zinc finger protein B
ZIC1 Zic family member 1
ZNF446 zinc finger protein 446
ZNF573 zinc finger protein 573
ZNF675 zinc finger protein 675
ZNF692 zinc finger protein 692
ZNF710 zinc finger protein 710
ZNF76 zinc finger protein 76
ZNF764 zinc finger protein 764
ZNHIT2 zinc finger, HIT-type containing 2