trichostatin A-5882 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the trichostatin A-5882 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ADRB2 adrenoceptor beta 2, surface
AGTR1 angiotensin II receptor, type 1
AHNAK2 AHNAK nucleoprotein 2
ANGPTL4 angiopoietin-like 4
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
AQP3 aquaporin 3 (Gill blood group)
ARG2 arginase 2
ARHGAP26 Rho GTPase activating protein 26
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASMTL acetylserotonin O-methyltransferase-like
BAMBI BMP and activin membrane-bound inhibitor
BEX1 brain expressed, X-linked 1
CCNA1 cyclin A1
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEP112 centrosomal protein 112kDa
COBL cordon-bleu WH2 repeat protein
COL21A1 collagen, type XXI, alpha 1
CPM carboxypeptidase M
CREB3L1 cAMP responsive element binding protein 3-like 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTGF connective tissue growth factor
CTH cystathionine gamma-lyase
CYR61 cysteine-rich, angiogenic inducer, 61
DBF4B DBF4 zinc finger B
DENND3 DENN/MADD domain containing 3
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
EFNA3 ephrin-A3
EPHA4 EPH receptor A4
EPHB2 EPH receptor B2
EPPK1 epiplakin 1
FABP4 fatty acid binding protein 4, adipocyte
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GMCL1 germ cell-less, spermatogenesis associated 1
GMPR guanosine monophosphate reductase
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GTF2B general transcription factor IIB
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HOXA1 homeobox A1
IGFBP7 insulin-like growth factor binding protein 7
IL1RAP interleukin 1 receptor accessory protein
IRS2 insulin receptor substrate 2
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIF5C kinesin family member 5C
KLHL25 kelch-like family member 25
LIFR leukemia inhibitory factor receptor alpha
LINC00341 long intergenic non-protein coding RNA 341
LIPG lipase, endothelial
LMCD1 LIM and cysteine-rich domains 1
MAK male germ cell-associated kinase
MAP2 microtubule-associated protein 2
MXD3 MAX dimerization protein 3
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NR4A1 nuclear receptor subfamily 4, group A, member 1
OASL 2'-5'-oligoadenylate synthetase-like
PCDH9 protocadherin 9
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDE4DIP phosphodiesterase 4D interacting protein
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PELI2 pellino E3 ubiquitin protein ligase family member 2
PLCD1 phospholipase C, delta 1
PLSCR4 phospholipid scramblase 4
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRPH peripherin
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB31 RAB31, member RAS oncogene family
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS17 regulator of G-protein signaling 17
RGS4 regulator of G-protein signaling 4
RND1 Rho family GTPase 1
RTN2 reticulon 2
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEPP1 selenoprotein P, plasma, 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SPTAN1 spectrin, alpha, non-erythrocytic 1
SQLE squalene epoxidase
SSBP2 single-stranded DNA binding protein 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STC1 stanniocalcin 1
STK4 serine/threonine kinase 4
STON1 stonin 1
STX7 syntaxin 7
SYT1 synaptotagmin I
SYT11 synaptotagmin XI
TNIK TRAF2 and NCK interacting kinase
TUBB2B tubulin, beta 2B class IIb
TUFT1 tuftelin 1
VWA5A von Willebrand factor A domain containing 5A
ZFP36 ZFP36 ring finger protein
ZNF280B zinc finger protein 280B

decreased expression

Symbol Name
ADGRG6 adhesion G protein-coupled receptor G6
ADNP activity-dependent neuroprotector homeobox
ADORA2B adenosine A2b receptor
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ATF1 activating transcription factor 1
BANP BTG3 associated nuclear protein
BCAR3 breast cancer anti-estrogen resistance 3
BCL7A B-cell CLL/lymphoma 7A
C12ORF43 chromosome 12 open reading frame 43
CBR3 carbonyl reductase 3
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHST10 carbohydrate sulfotransferase 10
CLCF1 cardiotrophin-like cytokine factor 1
COA7 cytochrome c oxidase assembly factor 7 (putative)
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DAXX death-domain associated protein
DENND1B DENN/MADD domain containing 1B
DEPDC1 DEP domain containing 1
DOLPP1 dolichyldiphosphatase 1
DSN1 DSN1, MIS12 kinetochore complex component
E2F8 E2F transcription factor 8
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
FAIM Fas apoptotic inhibitory molecule
FAR2 fatty acyl CoA reductase 2
FJX1 four jointed box 1 (Drosophila)
FST follistatin
GBX2 gastrulation brain homeobox 2
HAS2 hyaluronan synthase 2
HIRIP3 HIRA interacting protein 3
HLA-J major histocompatibility complex, class I, J (pseudogene)
HMGA2 high mobility group AT-hook 2
ICT1 immature colon carcinoma transcript 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFT81 intraflagellar transport 81
INHBB inhibin, beta B
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IPP intracisternal A particle-promoted polypeptide
JADE1 jade family PHD finger 1
KAT6B K(lysine) acetyltransferase 6B
KEAP1 kelch-like ECH-associated protein 1
KIF20A kinesin family member 20A
KIRREL kin of IRRE like (Drosophila)
KPTN kaptin (actin binding protein)
LIF leukemia inhibitory factor
LIPT1 lipoyltransferase 1
LRIF1 ligand dependent nuclear receptor interacting factor 1
LUC7L2 LUC7-like 2 (S. cerevisiae)
MCRS1 microspherule protein 1
MEPCE methylphosphate capping enzyme
MT1HL1 metallothionein 1H-like 1
NINJ1 ninjurin 1
NLRX1 NLR family member X1
NME6 NME/NM23 nucleoside diphosphate kinase 6
NMI N-myc (and STAT) interactor
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae)
NR2C2 nuclear receptor subfamily 2, group C, member 2
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
PCNT pericentrin
PLK1 polo-like kinase 1
POGK pogo transposable element with KRAB domain
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PTBP2 polypyrimidine tract binding protein 2
PXDC1 PX domain containing 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RIN2 Ras and Rab interactor 2
RPRD2 regulation of nuclear pre-mRNA domain containing 2
RSAD1 radical S-adenosyl methionine domain containing 1
SCAF8 SR-related CTD-associated factor 8
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SFMBT1 Scm-like with four mbt domains 1
SIM2 single-minded family bHLH transcription factor 2
SMAGP small cell adhesion glycoprotein
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SRSF4 serine/arginine-rich splicing factor 4
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STARD13 StAR-related lipid transfer (START) domain containing 13
STXBP3 syntaxin binding protein 3
TARBP2 TAR (HIV-1) RNA binding protein 2
TRIB3 tribbles pseudokinase 3
TRIM5 tripartite motif containing 5
TSEN2 TSEN2 tRNA splicing endonuclease subunit
USP21 ubiquitin specific peptidase 21
VEGFC vascular endothelial growth factor C
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
WDR18 WD repeat domain 18
WDR74 WD repeat domain 74
ZBED1 zinc finger, BED-type containing 1
ZC3H4 zinc finger CCCH-type containing 4
ZHX2 zinc fingers and homeoboxes 2
ZMYM3 zinc finger, MYM-type 3
ZNF16 zinc finger protein 16
ZNF165 zinc finger protein 165
ZNF692 zinc finger protein 692
ZNF787 zinc finger protein 787
ZNF84 zinc finger protein 84
ZZZ3 zinc finger, ZZ-type containing 3