trichostatin A-5802 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the trichostatin A-5802 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ADGRB2 adhesion G protein-coupled receptor B2
ADM adrenomedullin
ADRB2 adrenoceptor beta 2, surface
ANGPTL4 angiopoietin-like 4
AQP3 aquaporin 3 (Gill blood group)
ARG2 arginase 2
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASMTL acetylserotonin O-methyltransferase-like
BAMBI BMP and activin membrane-bound inhibitor
BEX1 brain expressed, X-linked 1
BIRC3 baculoviral IAP repeat containing 3
BMP2 bone morphogenetic protein 2
CA2 carbonic anhydrase II
CA5B carbonic anhydrase VB, mitochondrial
CCNA1 cyclin A1
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFAP69 cilia and flagella associated protein 69
CLDN1 claudin 1
CLIC3 chloride intracellular channel 3
CORO1A coronin, actin binding protein, 1A
CPM carboxypeptidase M
CREB3L1 cAMP responsive element binding protein 3-like 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTGF connective tissue growth factor
CTH cystathionine gamma-lyase
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DENND3 DENN/MADD domain containing 3
DFNB31 deafness, autosomal recessive 31
DNAAF1 dynein, axonemal, assembly factor 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EDN1 endothelin 1
EFNA3 ephrin-A3
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ENOX1 ecto-NOX disulfide-thiol exchanger 1
EPHA4 EPH receptor A4
FABP4 fatty acid binding protein 4, adipocyte
FGFR2 fibroblast growth factor receptor 2
FYN FYN proto-oncogene, Src family tyrosine kinase
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GMPR guanosine monophosphate reductase
H1FX H1 histone family, member X
HOXA1 homeobox A1
IL1RAP interleukin 1 receptor accessory protein
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
LMCD1 LIM and cysteine-rich domains 1
LPPR4 lipid phosphate phosphatase-related protein type 4
MAK male germ cell-associated kinase
MARK4 MAP/microtubule affinity-regulating kinase 4
MERTK MER proto-oncogene, tyrosine kinase
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NEU1 sialidase 1 (lysosomal sialidase)
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NME5 NME/NM23 family member 5
NMT2 N-myristoyltransferase 2
NR4A2 nuclear receptor subfamily 4, group A, member 2
OR10H1 olfactory receptor, family 10, subfamily H, member 1
PCDH7 protocadherin 7
PCDH9 protocadherin 9
PDE4DIP phosphodiesterase 4D interacting protein
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PELI1 pellino E3 ubiquitin protein ligase 1
PLK2 polo-like kinase 2
PLLP plasmolipin
PLSCR4 phospholipid scramblase 4
POU2F3 POU class 2 homeobox 3
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAI2 retinoic acid induced 2
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS17 regulator of G-protein signaling 17
RGS4 regulator of G-protein signaling 4
RND1 Rho family GTPase 1
RNF24 ring finger protein 24
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SIRT4 sirtuin 4
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STC1 stanniocalcin 1
STK17A serine/threonine kinase 17a
STON1 stonin 1
SYT1 synaptotagmin I
TAGLN3 transgelin 3
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRAFD1 TRAF-type zinc finger domain containing 1
TUBB2B tubulin, beta 2B class IIb
TUFT1 tuftelin 1
VWA5A von Willebrand factor A domain containing 5A
ZNF224 zinc finger protein 224

decreased expression

Symbol Name
ADNP activity-dependent neuroprotector homeobox
AP4M1 adaptor-related protein complex 4, mu 1 subunit
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARHGAP19 Rho GTPase activating protein 19
BANP BTG3 associated nuclear protein
BCAR3 breast cancer anti-estrogen resistance 3
BCL7A B-cell CLL/lymphoma 7A
C16ORF59 chromosome 16 open reading frame 59
C17ORF85 chromosome 17 open reading frame 85
C9ORF91 chromosome 9 open reading frame 91
CASD1 CAS1 domain containing 1
CBR3 carbonyl reductase 3
CCDC94 coiled-coil domain containing 94
CDT1 chromatin licensing and DNA replication factor 1
CLCF1 cardiotrophin-like cytokine factor 1
CPEB1 cytoplasmic polyadenylation element binding protein 1
CTCF CCCTC-binding factor (zinc finger protein)
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CUL1 cullin 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DEPDC1 DEP domain containing 1
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM193A family with sequence similarity 193, member A
FAM57A family with sequence similarity 57, member A
FJX1 four jointed box 1 (Drosophila)
FOXA1 forkhead box A1
FST follistatin
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GBX2 gastrulation brain homeobox 2
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GLTSCR1 glioma tumor suppressor candidate region gene 1
GMEB1 glucocorticoid modulatory element binding protein 1
GMEB2 glucocorticoid modulatory element binding protein 2
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HAS2 hyaluronan synthase 2
HDAC7 histone deacetylase 7
HMGA2 high mobility group AT-hook 2
HOXC10 homeobox C10
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IL4R interleukin 4 receptor
IL7R interleukin 7 receptor
INHBB inhibin, beta B
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
KAT6B K(lysine) acetyltransferase 6B
KEAP1 kelch-like ECH-associated protein 1
KIF14 kinesin family member 14
KLHL3 kelch-like family member 3
LIF leukemia inhibitory factor
LMNB1 lamin B1
LUC7L2 LUC7-like 2 (S. cerevisiae)
LY6G5C lymphocyte antigen 6 complex, locus G5C
MCM9 minichromosome maintenance complex component 9
MDC1 mediator of DNA-damage checkpoint 1
MEPCE methylphosphate capping enzyme
MID1IP1 MID1 interacting protein 1
NHEJ1 nonhomologous end-joining factor 1
NME6 NME/NM23 nucleoside diphosphate kinase 6
PAN2 PAN2 poly(A) specific ribonuclease subunit
PCDHGB5 protocadherin gamma subfamily B, 5
PCNT pericentrin
PEF1 penta-EF-hand domain containing 1
PHLDA3 pleckstrin homology-like domain, family A, member 3
PLK1 polo-like kinase 1
PPAN peter pan homolog (Drosophila)
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RIN2 Ras and Rab interactor 2
RPAP1 RNA polymerase II associated protein 1
SCAF8 SR-related CTD-associated factor 8
SH2D4A SH2 domain containing 4A
SLC12A8 solute carrier family 12, member 8
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLITRK5 SLIT and NTRK-like family, member 5
SMAGP small cell adhesion glycoprotein
SMYD5 SMYD family member 5
SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12)
SPHK1 sphingosine kinase 1
SRSF4 serine/arginine-rich splicing factor 4
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TRIM13 tripartite motif containing 13
URGCP upregulator of cell proliferation
VEGFC vascular endothelial growth factor C
VWA9 von Willebrand factor A domain containing 9
ZC3H4 zinc finger CCCH-type containing 4
ZC3H7A zinc finger CCCH-type containing 7A
ZFP69B ZFP69 zinc finger protein B
ZHX2 zinc fingers and homeoboxes 2
ZNF165 zinc finger protein 165
ZNF329 zinc finger protein 329
ZNF358 zinc finger protein 358
ZNF532 zinc finger protein 532
ZNF692 zinc finger protein 692
ZNF764 zinc finger protein 764
ZNF787 zinc finger protein 787
ZSCAN31 zinc finger and SCAN domain containing 31
ZZZ3 zinc finger, ZZ-type containing 3